Results 81 to 90 of about 1,334,194 (304)

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source

Human cerebrospinal fluid net flow enhanced by respiration during the awake state

Nature Communications
Cerebrospinal fluid dynamics play a crucial role in maintaining brain homeostasis by delivering nutrients, transmitting immune signals, and clearing waste products.
Seokbeen Lim, Petrice M. Cogswell, David N. Jacobson, Mahathi Kandimalla, Yurim Choi, Marin Nycklemoe, Daniel C. Kim, Pragalv Karki, Phillip J. Rossman, Zona McKenzie, John G. Park, Sangwon Lee, Sandeep Ganji, Walter K. Kremers, Ian T. Mark, Daehun Kang, Myung-Ho In, Jeffrey Gunter, Jonathan Graff-Radford, Eduardo E. Benarroch, John Huston, Clifford R. Jack, Ronald C. Petersen, Maria I. Lapid, Val J. Lowe, Daehyun Jung, Paul H. Min   +26 more
doaj   +1 more source

Morphological changes in cerebrospinal fluid production

Folia Morphologica
The ventricular system and subarachnoid space are filled with cerebrospinal fluid, which plays a key role in the nervous system. This fluid is produced by the choroid plexus, an organ rich in ion transporters that precisely control the transport of ...
Hubert Paszkowycz, Łukasz Olewnik, Bartosz Gonera, Robert Haładaj, Nicol Zielinska   +4 more
doaj   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Ventriculo caval shunt: a salvage alternative

Egyptian Journal of Neurosurgery
Hydrocephalus management is particularly challenging in patients with contraindications to conventional cerebrospinal fluid (CSF) diversion pathways. We report the case of a 37-year-old woman with obstructive hydrocephalus and a complex surgical history,
Santiago Diaz Pinillos, Enrique Monsalve Vargas, Juan Carlos Menendez, Mauricio Toscano Heredia, Jorge Azuero, Alejandro Cañas   +5 more
doaj   +1 more source

Importância do exame do liquor de controle em meningite bacteriana como critério de alta Importance of cerebrospinal fluid control tests in bacterial meningitis cases as a discharge criterion

Revista da Sociedade Brasileira de Medicina Tropical, 2008
Há controvérsias sobre indicação do exame do liquor de controle em pacientes recuperados clinicamente de meningite bacteriana como critério de cura. Alguns autores defendem alta hospitalar após normalização clínica e liqüórica, outros que a análise do ...
Diogo Buarque Cordeiro Cabral, Phelipe Cunha Bezerra, Demócrito de Barros Miranda Filho, Maria de Fátima Magalhães Acioly Mendizabal   +3 more
doaj   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

CEREBROSPINAL FLUID PRESSURE [PDF]

Journal of the American Medical Association, 1917
While there is included herewith the report of a case with data and pathologic material adding strong support to the theory that cerebrospinal fluid is a secretion from the choroid plexus cells, I trust that it may serve a purpose in another direction, namely, that it may encourage more frequent observations of spinal fluid pressure, and especially the
openaire   +2 more sources

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Breaking Barriers: Unveiling Sex-Related Differences in Cerebrospinal Fluid Analysis—A Narrative Review

Biology
(1) Background: The recent emphasis on sexual and gender diversity’s impact on human health underscores the need for tailored diagnostic and therapeutic approaches in neurology.
Raffaella Candeloro, Caterina Ferri, Tiziana Bellini, Maura Pugliatti, Massimiliano Castellazzi   +4 more
doaj   +1 more source