Results 131 to 140 of about 549,622 (359)

Cerebrospinal Fluid

, 1997
The analysis of cerebrospinal fluid (CSF) is described as the central nervous system equivalent of the complete blood count and the analogy is a good one. A CSF analysis provides a general index of neurologic health, and it often provides evidence of the presence of disease. Similar to a complete blood count, CSF analysis has reasonable sensitivity but
Bailey, Cleta Sue, Vernau, William
openaire   +2 more sources

A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra, Sara Bernal, David Almenta, Josefina Pérez‐Blanco, Valle Camacho, Isabel Sala, Mª Belén Sánchez‐Saudinós, Jesús García Castro, Judit Selma‐González, Miguel Ángel Santos‐Santos, Álvaro Carbayo, Janina Turon‐Sans, Ricard Rojas‐Garcia, Daniel Alcolea, Juan Fortea, Alberto Lleó, Oriol Dols‐Icardo, Ignacio Illán‐Gala   +17 more
wiley   +1 more source

Different cerebrospinal fluid drainage methods and chronic hydrocephalus in patients with aneurysmal subarachnoid hemorrhage

Frontiers in Neurology
BackgroundChronic hydrocephalus represents a common complication following aneurysmal subarachnoid hemorrhage (aSAH); however, the underlying mechanisms driving its pathogenesis remain incompletely understood.
Yang Zhou, Zhimin Liu, Huiqin Yan, Luyao Peng, Linshuang Chen, Wanyun Wu, Wei Luo, Yongkai Huang, Botao Wu   +8 more
doaj   +1 more source

Mathematical pressure volume models of the cerebrospinal fluid [PDF]

arXiv, 1996
Numerous mathematical models have emerged in the medical literature over the past two decades attempting to characterize the pressure and volume dynamics the central nervous system compartment. These models have been used to study he behavior of this compartment under such pathological clinical conditions s hydrocephalus, head injury and brain edema ...
arxiv  

Cerebrospinal fluid to serum glucose ratio in non-hypoglycorrhachic neurological conditions [PDF]

, 2005
Objective. To explore the relevance of cerebrospinal fluid to serum glucose ratio in non-hypoglycorrhachic conditions. Design. Retrospective observational study. Setting. Neurology ward, university teaching hospital, Hong Kong. Patients.
Chan, KH, Cheng, TS, Cheung, RTF, Ho, SL, Mak, W   +4 more
core  

Volumetric relief map for intracranial cerebrospinal fluid distribution analysis [PDF]

, 2015
International audienceCerebrospinal fluid imaging plays a significant role in the clinical diagnosis of brain disorders, such as hydrocephalus and Alzheimer's disease.
Decq, Philippe, Hodel, Jérôme, Kenmochi, Yukiko, Lebret, Alain, Petit, Éric, Rahmouni, Alain   +5 more
core   +3 more sources

Cerebrospinal Fluid

, 2008
This chapter discusses the anatomy, functions, and biochemistry of cerebrospinal fluid (CSF). CSF has four major functions: physical support of neural structures, excretion and “sink” action, intracerebral transport, and control of the chemical environment of the central nervous system.
Vernau, William, Vernau, Karen A., Sue Bailey, Cleta   +2 more
openaire   +2 more sources

Diagnostic Challenge in Frontal Variant Alzheimer's Disease With Low Amyloid‐β PET Retention

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diagnosing frontal variant Alzheimer's disease (fvAD) is difficult and could be even more difficult when amyloid‐beta (Aβ) PET retention is low. A 63‐year‐old woman presenting with a 3‐year history of apathy and memory impairment showed executive dysfunction, memory impairment, and severe bilateral frontotemporal atrophy on MRI.
Ryosuke Shimasaki, Masanori Kurihara, Kenji Ishibashi, Aya Midori Tokumaru, Kenji Ishii, Atsushi Iwata   +5 more
wiley   +1 more source

Phase 1, First‐In‐Human, Single‐/Multiple‐Ascending Dose Study of Iluzanebart in Healthy Volunteers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of iluzanebart, a fully human monoclonal antibody TREM2 (triggering receptor expressed on myeloid cells 2) agonist, after single‐ (SAD) and multiple‐ascending‐dose (MAD) administration.
Andreas Meier, Spyros Papapetropoulos, Andrew Marsh, Kelly Neelon, David Stiles, Ryan O'Mara, Evan A. Thackaberry, Marco Colonna, Raj Rajagovindan   +8 more
wiley   +1 more source

Epitope Mapping of Anti‐Neurofascin 155 Antibody in a Large Cohort of Autoimmune Nodopathy Patients

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune nodopathy (AN), a newly recognized disease entity, is an immune‐mediated polyneuropathy involving autoantibodies against cell adhesion molecules located in nodes of Ranvier and paranodal regions, such as neurofascin 186 (NF186) and neurofascin 155 (NF155). The present study aimed to identify the epitopes for autoantibodies
Amina A. Abdelhadi, Hidenori Ogata, Xu Zhang, Takumi Tashiro, Ryo Yamasaki, Jun‐ichi Kira, Noriko Isobe   +6 more
wiley   +1 more source