Results 131 to 140 of about 329,705 (242)

Insufficient cerebrospinal fluid penetration of tedizolid: a case report. [PDF]

JAC Antimicrob Resist
Brousse X, Lê MP, Lahouati M, Petitgas P.   +3 more
europepmc   +1 more source

SpaBatch: Deep Learning‐Based Cross‐Slice Integration and 3D Spatial Domain Identification in Spatial Transcriptomics

Advanced Science, EarlyView.
SpaBatch is an end‐to‐end multi‐slice spatial transcriptomics data integration framework. It simultaneously performs embedding learning, spatial feature denoising and reconstruction, batch effect correction, and spatial domain optimization, effectively correcting batch effects and achieving accurate 3D spatial domain identification.
Jinyun Niu, Donghai Fang, Jinyu Chen, Yi Xiong, Juan Liu, Wenwen Min   +5 more
wiley   +1 more source

Co-detection of mutations and methylations in cerebrospinal fluid ctdna for minimally-invasive diagnosis of brainstem glioma. [PDF]

J Exp Clin Cancer Res
Li T, Wang H, Wang Y, Mai Y, Wang P, Zhang M, Jiang Z, Xie L, Zhou H, Wang Y, Li X, Xiao D, Geng J, Wu W, Zhang P, Wang L, Wu Z, Zhang J, Cao D, Pan C, Zhang L.   +20 more
europepmc   +1 more source

An Automated Micro‐Immunobeads‐Based Electromagnetic Operation System (MEMOs) for Blood Testing of Alzheimer's Disease

Advanced Science, EarlyView.
This work presents an automated and accessible point‐of‐care device, MEMOs, for the detection of exosomal Aβ42 protein, a potential blood biomarker for Alzheimer’s disease. MEMOs, with its automated operation workflow, minimizes hands‐on time and maintains high sensitivity in diagnosing AD, allowing non‐specialists to conduct tests at home and offering
Xiaoxue Fan, Xinyu Ye, Jiangrui Xu, Tianjiao Mao, Ruotong Zhang, Xinyuan Zhou, Christina C. K. Au Yeung, Chang Li, Raymond Chuen‐Chung Chang, Haisong Lin, Ho Cheung Shum   +10 more
wiley   +1 more source

The Total and Diffusible Calcium of Serum and the Calcium of Cerebrospinal Fluid in Human Cases of Hypocalcemia and Hypercalcæmia. (Biochem. Journ., vol. xxvii, p. 1978, Dec, 1933.) Herbert, F. F. K. [PDF]

, 1934
G. W. T. H. Fleming
openalex   +1 more source

Erythrocyte Load in Cerebrospinal Fluid Linked with Hippocampal Atrophy in Alzheimer's Disease. [PDF]

J Clin Med
Christodoulou R, Vamvouras G, Lorentzen L, Vassiliou E.   +3 more
europepmc   +1 more source

Neurophilic Biomimetic Lipoprotein‐Mediated Targeted Nerve Growth Factor Delivery for Traumatic Brain Injury Therapy

Advanced Science, EarlyView.
Design of neurophilic biomimetic lipoprotein for intracerebral delivery of nerve growth factor (NGF) to traumatic brain injury (TBI). Nc‐rHDL@P can cross the BBB through ApoE3‐receptors interaction and target neurons via αRDP‐nAChR interaction. Nc‐rHDL@P delivers NGF to the lesion sites, rescues neurons, curbs inflammation, boosts sensorimotor and ...
Jialin Huang, Wenye Wang, Yidong Peng, Weiji Weng, Hanyu Wei, Qiyuan Feng, Antian Wang, Minjie Hu, Zhuoran Li, Shenyu Sun, Zhenghui He, Daiwen Zhang, Wenlan Qi, Yuhan Han, Zixuan Ma, Jiyuan Hui, Ru Gong, Yingwei Gao, Yong Lin, Jiyao Jiang, Xiaoling Gao, Junfeng Feng   +21 more
wiley   +1 more source

The Barrier between the Blood and Cerebrospinal Fluid. (Journ. Nerv, and Ment. Dis., vol. lxxix, p. 125, Feb., 1934.) Malamud, W., Miller, W. R., and Mullins, B. M. [PDF]

, 1934
G. W. T. H. Fleming
openalex   +1 more source

Cerebrospinal fluid microbiome revisited: no evidence of resident bacteria in archived samples. [PDF]

Microbiol Spectr
Ward A, Park H, Cheng B, Seeram D, Thakur KT, Uhlemann A-C, Noble JM, Papapanou PN.   +7 more
europepmc   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source