Results 151 to 160 of about 325,858 (289)

Blood α‐Synuclein Separates Parkinson's Disease from Dementia with Lewy Bodies

Annals of Neurology, EarlyView.
Objective Aggregation of misfolded α‐synuclein (aSyn) within the brain is the pathologic hallmark of Lewy body diseases (LBDs), including Parkinson's disease (PD), and dementia with Lewy bodies (DLB) disease. Although evidence exists for aSyn “strains,” conformations with distinct biological properties, biomarkers for PD versus DLB are lacking.
George T. Kannarkat, Rebecca Zack, R. Tyler Skrinak, James F. Morley, Roseanne Davila‐Rivera, Sanaz Arezoumandan, Katherine Dorfman, Kelvin Luk, David A. Wolk, Daniel Weintraub, Thomas F. Tropea, Edward B. Lee, Sharon X. Xie, Ganesh Chandrasekaran, Virginia M.‐Y. Lee, David Irwin, Rizwan S. Akhtar, Alice S. Chen‐Plotkin   +17 more
wiley   +1 more source

Harnessing the circadian nature of the choroid plexus and cerebrospinal fluid. [PDF]

NPJ Biol Timing Sleep
Fame RM.
europepmc   +1 more source

STUDIES ON THE PANDYʼS REACTION IN THE CEREBROSPINAL FLUID, ON THE INCONVENIENCES BY AS WELL AS THE INDICATIONS OF THE LUMBAR PUNCTURE IN SYPHILIS [PDF]

, 1920
Hugo A. J. M. de Wit
openalex   +1 more source

Cerebrospinal Fluid Metabolome in Central Nervous System Infections: A Study of Diagnostic Accuracy

Annals of Neurology, EarlyView.
Objective To assess the diagnostic accuracy of metabolites in cerebrospinal fluid (CSF) for central nervous system (CNS) infections. Methods Patients were derived from three prospective cohort studies in the Netherlands. All studies included adults suspected of a CNS infection who underwent a diagnostic lumbar puncture.
Steven L. Staal, Sabine E. Olie, Michel van Weeghel, Bauke V. Schomakers, Frédéric M. Vaz, I‐PACE Study Group, Diederik van de Beek, Matthijs C. Brouwer   +7 more
wiley   +1 more source

Potential cerebrospinal fluid metabolomic biomarkers and early prediction model for Parkinson's disease. [PDF]

Front Aging Neurosci
Zhang Y, Yan Y, Kong X, Zhang H, Su S.
europepmc   +1 more source

Metabolic Stress Expands Polyfunctional, Proinflammatory Th17 Cells in Patients With Psoriatic Arthritis for Whom There is Interleukin‐23–Independent Interleukin‐17 Production

Arthritis &Rheumatology, EarlyView.
Objective Genetic associations and blockade of the interleukin (IL)‐23/IL‐17 axis with monoclonal antibodies support a role for this pathway in patients with psoriatic arthritis (PsA). This study examines the requirement of IL‐23 for IL‐17 production and the role of the metabolic microenvironment in the expansion of Th17‐derived cells in patients with ...
Carmel B. Stober, Louise Ellis, Jane C. Goodall, Marc Veldhoen, J. S. Hill Gaston   +4 more
wiley   +1 more source

Composition and Neurogenetic Effects of Embryonic Cerebrospinal Fluid: A Systematic Review. [PDF]

Neuromolecular Med
Beldean AC, Moldovan RC, Sorițău O, Strilciuc Ș, Ciortea R, Mureșanu FD, Blesneag AV, Florian Ș, Bolunduț AC, Șușman S.   +9 more
europepmc   +1 more source

PSYCHOSIS WITH ENCEPHALITIS AND CEREBROSPINAL FLUID FINDINGS [PDF]

, 1922
Barnet Lemchen
openalex   +1 more source

Memory Gate Controlled by Contexts: Potential Key Structure That Could Link Small Associative Failures With Severe Cognitive Disorders

BioEssays, EarlyView.
Memory gate (MG) hypothesis assumes a neural structure that connects inputs to appropriate contexts. Panel A shows an input (green) that, in the MG, does not match the context (red): memory does not recognize it. Panel B shows that, in the MG, the context (green) matches the input: memory recognizes the pattern.
Eduardo Mizraji, Juan Lin, Andrés Pomi
wiley   +1 more source

Cutting‐Edge Aptasensing Approaches for Electrochemical Detection of Exosomes Utilizing MXenes

ChemElectroChem, EarlyView.
This work notably summarizes research on 2D MXenes/MXene's‐hybrid‐based nanoplatforms patterned with aptamers as an alternative to antibodies affording highly sensitive and robust biosensing of exosomes as well as their efficient isolation. The exosomes are highlighted as a valuable source of biomarkers and with the immobilization approaches of ...
Andrej Vikartovský, Natália Košútová, Lenka Lorencová, Peter Kasák, Tomáš Bertók, Ján Tkáč   +5 more
wiley   +1 more source