Results 11 to 20 of about 573,397 (359)

Analysis of reasons impairing the quality of cerebrospinal fluid cell slide centrifugal sedimentation examination method and its preventive measures

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2018
It is well known that cerebrospinal fluid (CSF) cell slide centrifugal sedimentation examination method is a very important technique for the etiological diagnosis of many central nervous system (CNS) diseases, especially for infectious diseases ...
Xiu-chu SU
doaj   +1 more source

Neurofilament light as a biomarker of axonal degeneration in patients with mild cognitive impairment and Alzheimer’s disease

open access: yesJournal of Integrative Neuroscience, 2021
Cerebrospinal fluid neurofilament light and plasma neurofilament light concentrations are elevated in patients with mild cognitive impairment and Alzheimer’s disease.
Yi Chen   +5 more
doaj   +1 more source

Ganciclovir penetrates into the cerebrospinal fluid of an infant with congenital cytomegalovirus infection [PDF]

open access: yes, 2015
Currently, there is no evidence whether ganciclovir, or its oral prodrug valganciclovir, penetrates into the cerebrospinal fluid of human infants treated for congenital cytomegalovirus infection.
Bizzarri, Bianca   +6 more
core   +2 more sources

Top-cited articles in cerebrospinal fluid leak (rhinorrhea and otorrhea) (1945–2018)

open access: yesBrazilian Journal of Otorhinolaryngology, 2021
Introduction: As scientific knowledge has grown in biomedicine, it has also become necessary to develop tools to manage and understand the body of evidence.
Irene Monjas-Cánovas   +4 more
doaj   +1 more source

Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid. [PDF]

open access: yes, 2016
BackgroundClinical diagnosis of parkinsonian syndromes like Parkinson's disease (PD), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) is hampered by overlapping symptomatology and lack of diagnostic biomarkers, and definitive ...
Boman, Andrea   +8 more
core   +1 more source

Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients. [PDF]

open access: yes, 2015
Quantification of disease-associated proteins in the cerebrospinal fluid (CSF) has been critical for the study and treatment of several neurodegenerative disorders; however, mutant huntingtin protein (mHTT), the cause of Huntington's disease (HD), is at ...
Andreas Weiss   +16 more
core   +1 more source

Drug transport in brain via the cerebrospinal fluid

open access: yesFluids and Barriers of the CNS, 2011
The human brain has no lymphatic system, but produces over a half-liter each day of cerebrospinal fluid. The cerebrospinal fluid is secreted at the choroid plexus and occupies the cavities of the four ventricles, as well as the cranial and spinal sub ...
Pardridge William M
doaj   +1 more source

Evaluation of microbial bacterial and fungal diversity in cerebrospinal fluid shunt infection. [PDF]

open access: yesPLoS ONE, 2014
Cerebrospinal fluid shunt infection can be recalcitrant. Recurrence is common despite appropriate therapy for the pathogens identified by culture. Improved diagnostic and therapeutic approaches are required, and culture-independent molecular approaches ...
Tamara D Simon   +8 more
doaj   +1 more source

Abnormal expression of cerebrospinal fluid cation chloride cotransporters in patients with Rett Syndrome [PDF]

open access: yes, 2013
Objective: Rett Syndrome is a progressive neurodevelopmental disorder caused mainly by mutations in the gene encoding methyl-CpG-binding protein 2. The relevance of MeCP2 for GABAergic function was previously documented in animal models. In these models,
Armstrong, Judith   +11 more
core   +4 more sources

Different intra-cerebrospinal distribution of linezolid in patients with inflammatory meningitis

open access: yesInternational Journal of Infectious Diseases, 2021
Linezolid has excellent antibiotic activity against gram-positive organisms and is expected to be an alternative to vancomycin for the treatment of bacterial meningitis.
Naoki Ichinose   +9 more
doaj   +1 more source

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