Results 11 to 20 of about 312,617 (268)
Top-cited articles in cerebrospinal fluid leak (rhinorrhea and otorrhea) (1945–2018)
Introduction: As scientific knowledge has grown in biomedicine, it has also become necessary to develop tools to manage and understand the body of evidence.
Irene Monjas-Cánovas +4 more
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Evaluation of microbial bacterial and fungal diversity in cerebrospinal fluid shunt infection. [PDF]
Cerebrospinal fluid shunt infection can be recalcitrant. Recurrence is common despite appropriate therapy for the pathogens identified by culture. Improved diagnostic and therapeutic approaches are required, and culture-independent molecular approaches ...
Tamara D Simon +8 more
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Drug transport in brain
The human brain has no lymphatic system, but produces over a half-liter each day of cerebrospinal fluid. The cerebrospinal fluid is secreted at the choroid plexus and occupies the cavities of the four ventricles, as well as the cranial and spinal sub ...
Pardridge William M
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Different intra-cerebrospinal distribution of linezolid in patients with inflammatory meningitis
Linezolid has excellent antibiotic activity against gram-positive organisms and is expected to be an alternative to vancomycin for the treatment of bacterial meningitis.
Naoki Ichinose +9 more
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Circulation of cerebrospinal fluid and interstitial fluid around the central nervous system and through the brain transports not only those water-like fluids but also any solutes they carry, including nutrients, drugs, and metabolic wastes. Passing through brain tissue primarily during sleep, this circulation has implications for neurodegenerative ...
Douglas H, Kelley, John H, Thomas
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Cerebrospinal fluid pressure [PDF]
The cerebrospinal fluid pressure at the foramen of Monro in man in the recumbent position is less than 100 mm water relative to atmospheric pressure. The oscillations in the pressure wave due to respiration and cardiac pulsation vary with the actual pressure and increase as the overall pressure rises.
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Background The central nervous system was previously thought to draw oxygen and nutrition from the arteries and discharge carbon dioxide and other metabolic wastes into the venous system.
Tetsuya Akaishi +10 more
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Cerebrospinal fluid dynamics [PDF]
The classical cerebrospinal fluid (CSF) circulation theory has been accepted as an established theory of CSF physiology. It describes bulk CSF flow from production site to absorption site. However, much controversy remains regarding the basic CSF physiology and the mechanisms behind the development of hydrocephalus.
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Background and objective The mortality rate of lung cancer meningeal metastasis is extremely high. Circulating tumor DNA (ctDNA) has been confirmed to be contain the genomic alterations present in tumors and has been used to monitor tumor progression and
Kunyu ZHANG +5 more
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BackgroundCarbapenem-resistant Klebsiella pneumoniae (CRKP) infections of the central nervous system (CNS) are associated with high mortality rates.
Wenkai Cong +5 more
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