Results 271 to 280 of about 562,738 (359)

Positive cerebrospinal fluid in the 2024 McDonald criteria for multiple sclerosis. [PDF]

EBioMedicine
Deisenhammer F, Hegen H, Arrambide G, Banwell BL, Coetzee T, Gnanapavan S, Montalban X, Tumani H, Willrich MA, Freedman MS.   +9 more
europepmc   +1 more source

Aneurysm Wall Enhancement and Probability of Instability in Unruptured Intracranial Aneurysms: A Long‐Term Follow‐Up Study

Annals of Neurology, EarlyView.
Objective Aneurysm wall enhancement (AWE) may predict aneurysm growth and rupture in the short‐term, but there is a lack of long‐term follow‐up studies. We aimed to determine whether unruptured intracranial aneurysms (UIAs) with AWE have a higher probability of aneurysm instability during long‐term follow‐up compared with those without AWE. Methods For
Laura T. van der Kamp, Maarten J. Kamphuis, Olivier Naggara, Thomas Le Tat, Gabriel J. E. Rinkel, Gérard A. P. de Kort, Ruben P. A. van Eijk, Jeroen Hendrikse, Irene C. van der Schaaf, Mervyn D. I. Vergouwen   +9 more
wiley   +1 more source

From Microbleeds to Iron: AI Prediction of Cerebrospinal Fluid Erythrocyte Load in Alzheimer's Disease. [PDF]

J Clin Med
Christodoulou RC, Vamvouras G, Sarquis MD, Petrou V, Papageorgiou PS, Rivera L, Morales Gonzalez C, Rivera G, Papageorgiou SG, Vassiliou E.   +9 more
europepmc   +1 more source

Serum p‐tau217 Is a Prognostic Indicator of Cognitive Impairment in Idiopathic REM Sleep Behavior Disorder

Annals of Neurology, EarlyView.
Objective Assess the performance of serum phosphorylated tau 217 (p‐tau217) and neurofilament light chain (NfL) in predicting risk of cognitive impairment or phenoconversion to dementia in individuals with iRBD. Methods We measured serum p‐tau217 and NfL levels by electrochemiluminescence across 4 polysomnographically confirmed iRBD cohorts (n = 300 ...
Shijun Yan, Anis Sahoo, Tanja Zerenner, Kenneth Marek, Michael Sommerauer, Wolfgang Oertel, Michele T. Hu, George K. Tofaris   +7 more
wiley   +1 more source

Diagnosis of Secondary Bacterial Meningitis via Aromatic Metabolites and Biomarkers in Cerebrospinal Fluid. [PDF]

Int J Mol Sci
Meinarovich PA, Sorokina EA, Beloborodova NV, Pautova AK.   +3 more
europepmc   +1 more source

AI‐Assisted Customizable SERS‐Based Aptasensor for Label‐Free, Rapid, and Sensitive Detection of Tau: Comparative Analysis Using Random Forest and Convolutional Neural Networks

Analysis &Sensing, EarlyView.
A customizable SERS‐based aptasensor platform integrates aptamer‐functionalized gold nanoparticles with machine learning models (RF and CNN) to detect tau protein, a key biomarker for Alzheimer's disease. This rapid, label‐free detection system achieves a detection limit of 100 pM, enabling early diagnosis and monitoring of disease progression.
Farbod Ebrahimi, Farshad Ebrahimi, Anjali Kumari, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Magnetic Resonance Imaging and Cerebrospinal Fluid Biomarker Clustering Defines Biological Subtypes of Alzheimer's Disease. [PDF]

Biomedicines
Christodoulou RC, Vamvouras G, Sarquis MD, Petrou V, Papageorgiou PS, Rivera L, Morales C, Rivera G, Vassiliou E, Solomou EE, Papageorgiou SG.   +10 more
europepmc   +1 more source

Delayed cerebrospinal fluid leak following lumbar interbody fusion caused by floating lamina: A case report. [PDF]

Medicine (Baltimore)
Tang B, Chen C, Zhang H, Feng J, Wu B, An Z, Dong L.   +6 more
europepmc   +1 more source

Immunological Profiling suggests an Association between Treg dysfunction and Pain in Knee Osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Background Pain is the hallmark symptom of osteoarthritis (OA) and its biological drivers remain poorly understood. While the role of innate immunity in OA has been extensively studied, the involvement of adaptive immunity, in particular regulatory T cells (Tregs), is not well understood. Methods We performed omics profiling of peripheral blood from 46
Marie Binvignat, Johanna Dubois, Maria Marco Salvador, Paul Stys, Fabien Pitoiset, Alexandra Roux, Michèle Sastre, Signe Hassler, Roberta Lorenzon, Claire Ribet, Vanessa Mhanna, Hélène Vantomme, Leslie Adda, Pierre Barennes, Nicolas Coatnoan, Kenz Le Gouge, Caroline Aheng, Alice Courties, Lise Minssen, Atul J. Butte, Adrien Six, Michelle Rosenzwajg, Nicolas Tchitchek, Francis Berenbaum, David Klatzmann, Encarnita Mariotti‐Ferrandiz, Jérémie Sellam   +26 more
wiley   +1 more source