Results 51 to 60 of about 1,334,194 (304)

Case Report: Cerebrospinal fluid eosinophilia in adult autoimmune GFAP astrocytopathy

Frontiers in Immunology
A 30-year-old Chinese male diagnosed with autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy presented with cerebrospinal fluid (CSF) eosinophilia.
Yuting Hou, Chunmei Zhao, Xu Wang
doaj   +1 more source

Distinguishing the cerebrospinal fluid cytokine profile in neuropsychiatric systemic lupus erythematosus from other autoimmune neurological diseases [PDF]

, 2015
Neuropsychiatric systemic lupus erythematosus (NPSLE) is a serious complication in SLE. Although the mechanism of NPSLE remains unclear, cytokines and chemokines are considered to be involved in their pathogenesis.
Shin-ya Kawashiri, Nakashima, Yoshikazu, Kawakami, Atsushi, Kazuhiko Arima, Takahisa Suzuki, Iwamoto, Naoki, Hideki Nakamura, Ushigusa, Takeshi, Tamai, Mami, Nishino, Ayako, Tomoki Origuchi, Masakatsu Motomura, Yoshikazu Nakashima, Suzuki, Takahisa, Kawashiri, Shin-ya, Horai, Yoshiro, Arima, Kazuhiko, Motomura, Masakatsu, Mami Tamai, Takeshi Ushigusa, Origuchi, Tomoki, Hideki Nakajima, Nakamura, Hideki, Ayako Nishino, Yoshiro Horai, Atsushi Kawakami, Naoki Iwamoto, Nakajima, Hideki, Ichinose, Kunihiro, Kunihiro Ichinose   +29 more
core   +1 more source

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo, Melissa Gerstle, Leah Cheng, Richard Cooper, Katherine Coyne, Claire Dusa, Naomi E. Joffe, Diana Schwarz, Sarah Steltz, Akiko Shimamura, Kasiani C. Myers, Thea Quinton   +11 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Evidence for normal extra-axial cerebrospinal fluid volume in autistic males from middle childhood to adulthood

NeuroImage, 2021
Autism spectrum disorder has long been associated with a variety of organizational and developmental abnormalities in the brain. An increase in extra-axial cerebrospinal fluid volume in autistic individuals between the ages of 6 months and 4 years has ...
Madeline Peterson, Molly B.D. Prigge, Erin D. Bigler, Brandon Zielinski, Jace B. King, Nicholas Lange, Andrew Alexander, Janet E. Lainhart, Jared A. Nielsen   +8 more
doaj   +1 more source

Why human color vision cannot reliably detect cerebrospinal fluid xanthochromia [PDF]

, 2005
Background - Visual assessment of cerebrospinal fluid (CSF) for xanthochromia ( yellow color) is practiced by the majority of laboratories worldwide as a means of diagnosing intracranical bleeds.Methods - Colorimetric and spectrophotometric analysis of ...
Sharpe, TL, Keir, G, Petzold, A
core  

Analytical performance and clinical utility of the INNOTEST (R) PHOSPHO-TAU(181P) assay for discrimination between Alzheimer's disease and dementia with Lewy bodies [PDF]

, 2006
Background: Total tau (T-tau) and beta-amyloid((1-42)) (A beta(1-42)) levels in cerebrospinal fluid (CSF) can differentiate Alzheimer's disease (AD) from normal aging or depressive pseudo-dementia.
Bläser, Miriam, Blennow, Kaj,, Vanderstichele, Hugo, Bürger, Katharina, Karen De Vreese, Anari, Lessia, Olsson, Annika Ohrfelt, Miriam Bläser, OLSSON AO, BLASER M, Eugeen Vanmechelen, Harald Hampel, DiLuca, Monica, BURGER K, ANDREASEN N, Christian Sindic, Niels Andreasen, Vanmechelen, Eugeen, Frank Hulstaert, PARNETTI L, LANARI A, VANDERSTICHELE H, Andreasen, Niels, DILUCA M, Katharina Bürger, Pottel, Hans, Öhrfelt Olsson, Annika,, Lanari, Alessia, Parnetti, Lucilla, DE VREESE K, Sindic, Christian, Hulstaert, Frank, Buerger, Katharina, PADOVANI, Alessandro, Monica DiLuca, De Vreese, Karen, Kaj Blennow, Ivanoiu, Adrian, POTTEL H, Padovani, Allesandro, BLENNOW K, Lucilla Parnetti, Annika Ohrfelt Olsson, Hans Pottel, HAMPEL H, Alessia Lanari, Allesandro Padovani, Hampel, Harald, Hugo Vanderstichele, SINDIC C, IVANOIU A, VANMECHELEN E., Blennow, Kaj, HULSTAERT F, Adrian Ivanoiu, Blennow, K, Lanari, A, Parnetti, L, Hampel, H, De, Vreese K, Andreasen, N,, Sindic, C, Vanderstichele, H, Ivanoiu, A, Buerger, K   +64 more
core   +2 more sources

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Evaluating the Effects of Cerebrospinal Fluid Protein Content on the Performance of Differential Pressure Valves and Antisiphon Devices Using a Novel Benchtop Shunting Model [PDF]

, 2020
BACKGROUNDHydrocephalus is managed by surgically implanting flow-diversion technologies such as differential pressure valves and antisiphoning devices; however, such hardware is prone to failure.
Beharry, Kelly, Wataru Ishida, Iyer, Rajiv, Um, Richard, Perdomo-Pantoja, Alexander, Xu, Risheng, Bayston, Roger, Tyler, Betty, Richard Um, Audrey Monroe, Ye, Xiaobu, Noah L Gorelick, Rajiv Iyer, Betty Tyler, Alexander Perdomo-Pantoja, Risheng Xu, Xiaobu Ye, Serra, Riccardo, Kroll, Francesca, Riccardo Serra, Hannah Antoine, Arba Cecia, Luciano, Mark G, Gorelick, Noah L, Cecia, Arba, Mark G Luciano, Antoine, Hannah, Roger Bayston, Francis Loth, Grewal, Angad, Suk, Ian, Ian Suk, Monroe, Audrey, Kelly Beharry, Francesca Kroll, Ishida, Wataru, Loth, Francis, Angad Grewal   +37 more
core   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source