Results 211 to 220 of about 395,728 (365)

Disease Characteristics and Treatments Associated with Outcome in Primary Angiitis of the Central Nervous System—A Multicenter Cohort Study in 163 Patients

Annals of Neurology, EarlyView.
Objective The aim was to determine patient, disease, and treatment characteristics associated with outcome in patients with primary angiitis of the central nervous system (PACNS) in a large multicenter German cohort. Methods In a retrospective, observational cohort study, we analyzed 163 adult patients who met the diagnostic criteria for PACNS.
Anna Lena Fisse, Nadine Bonberg, Carolin Beuker, Claudia Pfeuffer, Andreas Heidenreich, Christina Krüger, Milani Deb‐Chatterji, Jana Becker, Stefan T. Gerner, Clemens Küpper, Louisa Nitsch, Roxane‐Isabelle Kestner, Lars Udo Krause, Juliane Herm, Alexander Katalinic, André Karch, Ralf Gold, Heinz Wiendl, Wolf‐Rüdiger Schäbitz, Gabor C. Petzold, Waltraud Pfeilschifter, Marius Ringelstein, Thorsten R. Doeppner, Lars Kellert, Hagen B. Huttner, Markus Kraemer, Tim Magnus, Karl Georg Haeusler, Heike Minnerup, Jens Minnerup   +29 more
wiley   +1 more source

The FindMNDBiomarker Program: Protein Changes in Motor Neuron Disease/Amyotrophic Lateral Sclerosis Postmortem Tissue and Biofluids

Annals of Neurology, EarlyView.
Objective Biomarkers of disease pathogenesis are critically needed for amyotrophic lateral sclerosis (ALS) to facilitate diagnosis and patient stratification into appropriate therapeutic trials. Proteomic studies offer significant potential to advance this, but reproducibility across laboratories is a key component toward identifying protein changes ...
Gabrielle L. Adler, Matthew C. Kiernan, Rachel H. Tan   +2 more
wiley   +1 more source

Exenatide Once Weekly in the Treatment of Patients with Multiple System Atrophy

Annals of Neurology, EarlyView.
Objective Exenatide, a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, has neuroprotective effects in preclinical models of multiple system atrophy (MSA). We investigated these effects in a proof‐of‐concept clinical trial. Methods In this single‐center, randomized, open label trial, participants with MSA were randomly assigned (1:1) to receive ...
Nirosen Vijiaratnam, Christine Girges, Martin Wiegand, Claudia Ismail, Alexandra Lameirinhas, Alison Yarnall, Cameron Kirk, Silvia Del‐Din, Lynn Rochester, Christopher Kobylecki, Gareth Ambler, Simon Skene, Henry Houlden, Viorica Chelban, Amanda Heslegrave, Wendy Phillips, Alan Whone, Niall Quinn, Christian Lambert, Charlotte Dore, Huw R. Morris, Mathew H. Horrocks, Ji Eun Lee, Judi O'Shaughnessy, Yazhou Li, Nigel H. Greig, Sonia Gandhi, Vincenzo Libri, Dilan Athauda, Tom Foltynie   +29 more
wiley   +1 more source

Endothelium-dependent vasoectivation of canine cerebral artery by cerebrospinal fluid (CSF) obtained from the patients suffered from subarachnoid hemorrhage (SAH)

, 1987
Hachiro Usui, Motohatsu Fujiwara, Hiroaki Shirahase, Shinichiro Okamoto, Kazuyoshi Kurahashi   +4 more
openalex   +1 more source

Title: Beta2-Microglobulin (B2M) Concentrations in Cerebrospinal Fluid (CSF) Correlate with Neurodevelopmental Outcome in Newborns with Symptomatic Congenital Cytomegalovirus Infection (SCCI) [PDF]

, 2011
Ana Alarcón, Miriam Martínez-Biarge, Ángel Hernánz, J Quero, Alfredo García‐Alix   +4 more
openalex   +1 more source

Parasagittal dural space and cerebrospinal fluid (CSF) flow across the lifespan in healthy adults. [PDF]

Fluids Barriers CNS, 2022
Hett K, McKnight CD, Eisma JJ, Elenberger J, Lindsey JS, Considine CM, Claassen DO, Donahue MJ.   +7 more
europepmc   +1 more source

Targeted Proteomics upon Treatment with Tofersen Identifies Novel Response Markers for Superoxide Dismutase 1‐Linked Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objective Tofersen is the first effective and approved therapy for superoxide dismutase 1 (SOD1)‐associated amyotrophic lateral sclerosis (ALS [SOD1‐ALS]). Following treatment with tofersen, neurofilament levels in patients' cerebrospinal fluid (CSF) and serum seem to respond earlier than clinical parameters.
Christina Steffke, Karthik Baskar, Franziska Bachhuber, Maximilian Wiesenfarth, Johannes Dorst, Joachim Schuster, Florian Schöberl, Peter Reilich, Martin Regensburger, Alexander German, René Günther, Maximilian Vidovic, Susanne Petri, Thomas Meyer, Tim Hagenacker, Julian Grosskreutz, Ute Weyen, Patrick Weydt, Thomas Haarmeier, Paul Lingor, Joachim Wolf, Andreas Hermann, Johannes Prudlo, Kornelia Günther, Antje Knehr, Zeynep Elmas, Zeljko Uzelac, Simon Witzel, Wolfgang Philipp Ruf, Axel Freischmidt, Ritchie Ho, Albert C. Ludolph, Jochen H. Weishaupt, Hayrettin Tumani, Patrick Oeckl, David Brenner, Alberto Catanese   +36 more
wiley   +1 more source

Cerebrospinal fluid (CSF) boosts metabolism and virulence expression factors in Acinetobacter baumannii [PDF]

, 2020
Jasmine Martinez, Chelsea Razo-Gutierrez, Casin Le, Robert Courville, Camila Pimentel, Christine Liu, Sammie E. Fuang, Alejandro J. Vila, Parvin Shahrestani, Verónica Jiménez, Marcelo E. Tolmasky, Scott A. Becka, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Alfonso Soler‐Bistué, Rodrigo Sieira, María Soledad Ramírez   +16 more
openalex   +1 more source

Persistent CSF leak post spinal surgery and cerebrospinal fluid dynamic disturbances: cause or consequence? [PDF]

, 2015
Claudia Craven, Neekhil A Patel, Akbar Ali Khan, Simon D Thompson, Edward Dyson, Samir Matloob, Ajai Chari, Patricia Haylock-Vize, Syed Nisar Hussain Shah, Andrew R. Stevens, Tarek Mostafa, Huan Chan, Jinendra Ekanayake, Ahmed K. Toma, Laurence Watkins   +14 more
openalex   +1 more source

Detection of Glioma-Related Hotspot Mutations Through Sequencing of Cerebrospinal Fluid (CSF)-Derived Circulating Tumor DNA: A Pilot Study on CSF-Based Liquid Biopsy for Primary Spinal Cord Astrocytoma. [PDF]

Neurospine, 2023
Cheng L, Duan W, Guan J, Wang K, Liu Z, Wang X, Wang Z, Wu H, Chen Z, Jian F.   +9 more
europepmc   +1 more source