This review explores pathological disulfide‐crosslinking as a key driver of amyloidogenic protein misfolding and aggregation. Oxidative and ER stress pathways contributing to disease progression are discussed and emerging therapeutic strategies targeting disulfide‐linked aggregates in neurodegenerative and systemic amyloid diseases are examined ...
Dong Min Kang+4 more
wiley +1 more source
Cutting‐Edge Aptasensing Approaches for Electrochemical Detection of Exosomes Utilizing MXenes
This work notably summarizes research on 2D MXenes/MXene's‐hybrid‐based nanoplatforms patterned with aptamers as an alternative to antibodies affording highly sensitive and robust biosensing of exosomes as well as their efficient isolation. The exosomes are highlighted as a valuable source of biomarkers and with the immobilization approaches of ...
Andrej Vikartovský+5 more
wiley +1 more source
Assessment of Cerebrospinal Fluid (CSF) to Differentiate between Bacterial Meningitis and Viral Meningitis [PDF]
Shahriar Ahmed+6 more
openalex +1 more source
Manganese Neurotoxicity and Familial Disorders of Manganese Transport
ABSTRACT Manganese is the 12th most common element in the Earth's crust and is an essential industrial component. Biologically, this metal plays an important role as a constituent of numerous enzymes. While manganese is required for normal biochemical and physiological processes, manganese excess can lead to significant toxicity, particularly to the ...
Sidney M. Gospe Jr.
wiley +1 more source
Pseudotumor Cerebri Syndrome Without Headache in an Obese Male With Eight Restricted Cerebrospinal Fluid (CSF) Oligoclonal Bands: A Case Report. [PDF]
Yousaf MIK+4 more
europepmc +1 more source
Cerebrospinal Fluid (CSF) Exchange with Artificial CSF Enriched with Mesenchymal Stem Cell Secretions Ameliorates Experimental Autoimmune Encephalomyelitis [PDF]
Michael Valitsky+7 more
openalex +1 more source
Delayed Neuropsychiatric Syndrome Due to Unrecognized Carbon Monoxide Toxicity: A Case Report
ABSTRACT Introduction Carbon monoxide (CO) is a leading cause of poison‐related deaths in children and frequently results in nonspecific neurological symptoms and imaging findings. Rarely, pediatric patients develop a delayed neuropsychiatric syndrome (DNS) following a lucid interval.
Alexandria Valdrighi+3 more
wiley +1 more source
Chemokine associations with blood cerebrospinal fluid (CSF) barrier permeability and delirium. [PDF]
Denver P+11 more
europepmc +1 more source
Cerebrospinal fluid (CSF) augments metabolism and virulence expression factors in Acinetobacter baumannii. [PDF]
Martinez J+18 more
europepmc +1 more source