Results 141 to 150 of about 15,922 (213)

Minimally Invasive Approaches to Spinal Cerebrospinal Fluid Leak Repair: Current Strategies and a Novel Technique. [PDF]

J Pers Med
Khalafallah AM, Sanghera BS, Kader M, Boddu JV, Urakov T.   +4 more
europepmc   +1 more source

Targeting Mitochondria in Aging‐Related Diseases: Therapeutic Potential and Obstacles

MedComm, Volume 7, Issue 6, June 2026.
This article systematically summarized the specific mechanism of aging‐related diseases caused by mitochondrial dysfunction, and summarized the broad‐spectrum treatment methods and disease targeted treatment strategies for mitochondria. At the same time, it also pointed out the dilemma faced by mitochondrial targeted treatment.
Zijie Xiang, Yu Chen, Xishui Liu, Haowen Lu, Yuqing Yang, Lei Xing, Yu Zhang, Chuandong Lang, Siming Zhang, Shixiang Zhao, Youzhi Hong, Jiaxiang Bai, Yusen Qiao   +12 more
wiley   +1 more source

Intradural Repair of Temporal Bone Encephalocele and Cerebrospinal Fluid Leak: Results from a Single Institution. [PDF]

J Neurol Surg B Skull Base
Ellsperman SE, D'Agostino AK, Olszewski AM, Peng KA, Slattery WH, Lekovic GP.   +5 more
europepmc   +1 more source

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

MedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang, Jingfei Shi, Linlin Xu, Guangrui Zhao, Yue Chen, Lin Cheng, Xiaokang Li, Zhigang Sun, Shuhong Huang   +8 more
wiley   +1 more source

Repair of a ventral cervical cerebrospinal fluid leak via a single-level anterior cervical discectomy and fusion without corpectomy: illustrative case. [PDF]

J Neurosurg Case Lessons
Maxin AJ, Pistone TS, Sattur MG, Borg N.
europepmc   +1 more source

Distinct Effects of Nonselective Rho‐Kinase Inhibitor Fasudil and Selective Rho‐Kinase 2 Inhibitor KD025 on Serotonin and Dopamine Release in the Nucleus Accumbens of Mice

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Fasudil perfusion in the NAc increased basal extracellular serotonin but not dopamine, and suppressed depolarization‐evoked release of both. In contrast, KD025 showed minimal effects on basal levels and selectively suppressed evoked serotonin release. ABSTRACT Recent studies have indicated that the Rho GTPase family and Rho‐kinases are associated with ...
Rinako Tanaka, Wenjun Zhu, Taku Nagai, Toshitaka Nabeshima, Kozo Kaibuchi, Norio Ozaki, Hiroaki Ikesue, Hiroyuki Mizoguchi, Kiyofumi Yamada   +8 more
wiley   +1 more source

The Impact of Venous Stenting on Symptoms and Quality of Life in Patients with Idiopathic Intracranial Hypertension and Spontaneous Cerebrospinal Fluid Leak. [PDF]

J Neurol Surg B Skull Base
Mandloi S, Nisar A, Shing SR, Kahn C, Benedict PA, Duffy A, Naamani KE, Bray D, Gooch MR, Toskala E, Evans J, Farrell C, Rosen M, Rabinowitz MR, Yuan H, Nyquist GG.   +15 more
europepmc   +1 more source

Biophysical assessment of the molecular mechanisms of Tau aggregation and its role in Alzheimer's disease

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Alzheimer's disease (AD) is characterized by the intracellular aggregation of the microtubule‐associated protein Tau. While the presence of large, insoluble neurofibrillary tangles has long been the primary focus of this research, a paradigm shift in the field now highlights smaller, soluble oligomers as the more neurotoxic Tau species leading
Joshua T. Skrehot, Dmitry Kurouski
wiley   +1 more source

Chronic cerebrospinal fluid leak can cause amyotrophic lateral sclerosis mimic. [PDF]

J Gen Fam Med
Saito S, Ikeguchi R, Kitagawa K.
europepmc   +1 more source

Cerebrospinal Fluid Leak Prevention in Intradural Spine Surgery: A Long Series Analysis of Closure with Non-Penetrating Titanium Clips. [PDF]

Brain Sci
Anselmi L, Anania CD, Ubezio MC, Farinaro G, Creatura D, Ortolina A, Tomei M, Baram A, Fornari M.   +8 more
europepmc   +1 more source