Results 161 to 170 of about 183,231 (359)

Synovial Fluid‐derived Micrococcus Luteus G18 Exacerbates Osteoarthritis Progression by Promoting Chondrocyte Degradation via TLR2/JNK/AP‐1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
Traditionally considered sterile, the articular cavity is now recognized to harbor microbial communities influencing osteoarthritis (OA). Integrating 16S rRNA sequencing and culturomics, Micrococcus luteus is enriched in advanced OA. Notably, M. luteus G18 exacerbates cartilage degeneration via TLR2/JNK/AP‐1‐mediated ECM disruption, revealing intra ...
Tingtao Chen   +6 more
wiley   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

open access: yesAdvanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

A Quantitative Systems Pharmacology Model That Describes Neurofilament Light Dynamics During Alzheimer's Disease Progression

open access: yesCPT: Pharmacometrics & Systems Pharmacology
Neurofilament proteins are important constituents of neuronal cytoskeleton, along with microtubules. An increased concentration of neurofilament light (NfL) protein in cerebrospinal fluid (CSF) and plasma is considered a potential biomarker of axonal ...
Polina Maliukova, Tatiana Karelina
doaj   +1 more source

Evaluation of cerebrospinal fluid proteins as potential biomarkers for early stage Parkinson's disease diagnosis. [PDF]

open access: yesPLoS One, 2018
Dos Santos MCT   +12 more
europepmc   +1 more source

Cerebrospinal Fluid Tau Protein Levels and <sup>18</sup>F-Fluorodeoxyglucose Positron Emission Tomography in the Differential Diagnosis of Alzheimer’s Disease [PDF]

open access: bronze, 2010
Igor Yakushev   +7 more
openalex   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

open access: yesAdvanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen   +10 more
wiley   +1 more source

Comparison Of Methods For The Quantification Of Albumin In Serum And Total Protein In Cerebrospinal Fluid

open access: yesRevista Cubana de Investigaciones Biomédicas, 2019
Introduction: Albumin is the protein that marks the passage of cerebrospinal fluid proteins into the serum. Materials and methods: Serum albumin was quantified by bromocresol green dye technique and by using the modified microalbuminuria method and for
Vanessa Pérez-del-Vallìn   +6 more
doaj  

Cerebrospinal fluid amyloid beta and glial fibrillary acidic protein concentrations in Huntington’s disease [PDF]

open access: gold, 2021
Sara Korpela   +6 more
openalex   +1 more source

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