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Neuroscience Letters, 2010
Studies have shown that ageing and several neurological diseases of the central nervous system are often accompanied with increase in concentrations of many cerebrospinal fluid (CSF) proteins. However, few studies have actually looked into the mechanisms behind the increase in CSF protein concentrations. In this study, CSF secretion rates and turnovers
Chen, Carl P. C. +2 more
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Studies have shown that ageing and several neurological diseases of the central nervous system are often accompanied with increase in concentrations of many cerebrospinal fluid (CSF) proteins. However, few studies have actually looked into the mechanisms behind the increase in CSF protein concentrations. In this study, CSF secretion rates and turnovers
Chen, Carl P. C. +2 more
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Protein Analyses in Cerebrospinal Fluid
European Neurology, 1993Concentration gradients in lumbar cerebrospinal fluid (CSF) for albumin and IgG were studied in 8 healthy individuals and 44 neuropsychiatric patients by serial sampling of 6 successive portions of CSF, each containing 4 ml, in all 24 ml. Significant and identical decreases between the first (0-4th ml) and the last (21st-24th ml) portions were found ...
Kaj Blennow +5 more
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The Cerebrospinal Fluid Proteins in Multiple Sclerosis
Clinics in Laboratory Medicine, 1986A specific and reliable diagnostic test for MS does not currently exist. However, most patients afflicted with this disorder demonstrate both qualitative and quantitative changes in CSF proteins. An abnormal immunoglobulin fraction synthesized within the CNS is frequently found to be electrophoretically distinct from other proteins of the CSF and ...
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Cerebrospinal fluid tau proteins in status epilepticus
Epilepsy & Behavior, 2015Tau protein is a phosphorylated microtubule-associated protein, principally localized at neuronal level in the central nervous system (CNS). Tau levels in the cerebrospinal fluid (CSF) are considered to index both axonal and neuronal damage. To date, however, no study has specifically evaluated the CSF levels of tau proteins in patients with status ...
Giada Giovannini +12 more
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The protein content of cerebrospinal fluid in trypanosomiasis
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1948Summary 1. The two common methods of estimation of total protein in the cerebrospinal fluid are the Precipitation (Sicard and Cantaloube) and Turbidometric (Opacity) methods. 2. Experience in the author's laboratory shows that the results given by the Opacity method tend to be one and a half to two times those given by the Precipitation ...
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Analysis of cerebrospinal fluid proteins by electrophoresis
Journal of Chromatography B: Biomedical Sciences and Applications, 1991The cerebrospinal fluid (CSF) is a specific ultrafiltrate of plasma, which surrounds the brain and spinal cord. The study of its proteins and their alteration may yield useful information on several neurological diseases. By using various electrophoretic separation techniques, several CSF proteins have been identified derived from plasma or from brain.
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Separation of cerebrospinal fluid-enriched proteins
Journal of the Neurological Sciences, 1983Beta-trace protein, beta2-microglobulin and prealbumin were identified in a cerebrospinal fluid fraction containing proteins enriched in CSF-characteristic proteins obtained through affinity chromatography. The prealbumin amount was somewhat higher among CSF-enriched proteins from ventricular CSF than in the same fraction from lumbar CSF.
Christian Blomstrand +4 more
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PROTEINS IN SERUM AND CEREBROSPINAL FLUID IN DEMENTED PATIENTS
Acta Neurologica Scandinavica, 2009Sixteen plasma proteins, including the immunoglobulins, were determined in cerebrospinal fluid (CSF) and serum from 12 demented patients. Furthermore, the total protein content was measured, haptoglobin was typed and serum was tested for precipitins against water-extractable human brain antigens.
Ole J. Rafaelsen +2 more
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Cerebrospinal Fluid Protein Patterns in Spasmodic Torticollis
European Neurology, 1975In order to investigate the value of CSF-protein analyses in spasmodic torticollis CSF from six patients with probable organic and two patients with probable psychogenic torticollis was examined by isoelectric focusing and electrophoresis. In all the patients with organic torticollis two pathological CSF-protein fractions were found in the alkaline ...
K.G. Kjellin, H. Stibler
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Myelin basic protein in cerebrospinal fluid and other body fluids
Multiple Sclerosis, 1998Myelin basic protein (MBP) or a fragment thereof may enter cerebrospinal fluid (CSF) and other body fluids in an etiologically nonspecific fashion to provide information about the status of central nervous system (CNS) myelin damage. MBP immunochemically detected is referred to as MBP-like material (MBPLM).
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