Results 31 to 40 of about 167,231 (225)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

Chiari I Malformation: Review and Update of Current Treatment Options

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo   +11 more
wiley   +1 more source

Centromedian nucleus targeting in the pediatric population treated with thalamic responsive neurostimulation for drug‐resistant epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract The management of drug‐resistant epilepsy (DRE) in the pediatric population using neurostimulation of the centromedian (CM) nucleus of the thalamus (CMN) has been reported to be effective and safe. We present a case series of pediatric patients treated with responsive neurostimulation (RNS) and report on contact localization in relation to ...
Marian Michael Bercu   +8 more
wiley   +1 more source

CSF Ascites: Review of articles and a case presentation

open access: yesJournal of Research in Medical Sciences, 2005
Cerebrospinal fluid (CSF) ascites is a rare complication after ventriculopritoneal (VP) shunts. Most patients have gradual abdominal protrusion without any neurological sign or symptom of shunt malfunction.
R Pourkhalili, A Mirhosseini, H Khalili
doaj  

Clinical and Radiological Evolution of Idiopathic Normal Pressure Hydrocephalus: A Critical Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background The pathophysiology of idiopathic normal pressure hydrocephalus (iNPH) remains poorly understood. While it is commonly accepted that iNPH has an insidious onset, little is known about its preclinical and early stages and its development over time.
David Campo‐Caballero   +6 more
wiley   +1 more source

Human CNTNAP1 Variants Associated With Severe Neurological Deficits: Additional Cases and Literature Review

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT CNTNAP1 encodes the Contactin‐Associated Protein 1 (CNTNAP1), also known as Caspr1, which is a transmembrane protein critical for nervous system function. CNTNAP1 is localized to the paranodal regions of all myelinated axons, flanking either side of the node of Ranvier.
Lacey B. Sell   +8 more
wiley   +1 more source

Epidural hematoma after ventriculoperitoneal shunt surgery: report of two cases

open access: yesArquivos de Neuro-Psiquiatria, 1998
Ventriculoperitoneal shunt operations represent the most used choice for treating hydrocephalus, although some related complications have been reported.
PEREIRA CARLOS UMBERTO   +3 more
doaj  

Minimally Invasive Treatment of Idiopathic Syringomyelia Using Myringotomy T-Tubes: a Case Report and Technical Note

open access: yesActa Clinica Croatica, 2020
Syringomyelia is characterized by a fluid-filled cavity within the spinal cord. Expansion of the syrinx often results in the clinical course of progressive neurologic deficit.
Domagoj Jugović   +3 more
doaj   +1 more source

No increased risk of spinal cerebrospinal fluid leak after spinal manipulative therapy: A retrospective cohort study

open access: yesPM&R, EarlyView.
Abstract Background Spinal cerebrospinal fluid (CSF) leaks, a rare but debilitating condition, have been described following spinal manipulative therapy (SMT) in case reports. However, the nature of the potential association between SMT and CSF leak is uncertain, and symptoms such as neck pain or headache may reflect preexisting leaks rather than ...
Robert J. Trager   +4 more
wiley   +1 more source

Ventriculoperitoneal shunt complications: a local study at Qena University Hospital: a retrospective study

open access: yesEgyptian Journal of Neurosurgery, 2018
Background Shunting of cerebrospinal fluid (CSF) has reduced the morbidity and mortality of hydrocephalus. Ventriculoperitoneal (VP) shunt is the most commonly used procedure for shunting, but it has potential complications that may need multiple ...
Ali R. Hamdan
doaj   +1 more source

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