Results 211 to 220 of about 58,328 (279)

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

open access: yesAdvanced Science, Volume 12, Issue 27, July 17, 2025.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin   +21 more
wiley   +1 more source

Plasma placental growth factor as a biomarker for subcortical ischemic vascular dementia and its cognitive correlation mediated by white matter hyperintensities

open access: yesAlzheimer's &Dementia, Volume 21, Issue 7, July 2025.
Abstract INTRODUCTION Placental growth factor (PlGF) was recently shown to be associated with cerebrovascular and neurodegenerative diseases. The changes of PlGF level in patients with subcortical ischemic vascular dementia (SIVD) and its associations with cognitive function remain unclear.
Ping Che   +7 more
wiley   +1 more source

Proteomic Profiling of the Large‐Vessel Vasculitis Spectrum Identifying Shared Signatures of Innate Immune Activation and Stromal Remodeling

open access: yesArthritis &Rheumatology, Volume 77, Issue 7, Page 884-900, July 2025.
Objective Takayasu arteritis (TAK) and giant cell arteritis (GCA), the most common forms of large‐vessel vasculitis (LVV), can result in serious morbidity. Understanding the molecular basis of LVV should aid in developing better biomarkers and treatments. Methods Plasma proteomic profiling of 184 proteins was performed in two cohorts. Cohort 1 included
Robert T. Maughan   +15 more
wiley   +1 more source

The Therapeutic Effects of Acorus Tatarinowii Volatile Oil and Electroacupuncture in Post‐Stroke Cognitive Impairment Patients: A Clinical Trial Protocol

open access: yesBrain and Behavior, Volume 15, Issue 7, July 2025.
Conceptual schematic illustrating the trial design and mechanisms. Electroacupuncture (EA) targets cervical acupoints (GB20/Gongxue) to improve cerebral blood flow and neural connectivity. HOT (herbal olfactory therapy) delivers Acorus Tatarinowii volatile oil via inhalation to penetrate the blood‐brain barrier, reduce neuroinflammation, and enhance ...
Ying Dandan   +4 more
wiley   +1 more source

Impact of Dietary Patterns on Migraine Management: Mechanisms of Action and Recent Literature Insights

open access: yesBrain and Behavior, Volume 15, Issue 7, July 2025.
ABSTRACT Purpose Migraine headaches are a common and debilitating neurological disorder that significantly impacts the quality of life of affected individuals. Dietary patterns have been increasingly recognized as potential factors in the prevention and management of migraines. This comprehensive review aims to provide a comparative analysis of various
Vahideh Behrouz, Elnaz Hakimi, Elias Mir
wiley   +1 more source

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