Results 41 to 50 of about 620,761 (232)

Association between non-traditional lipid parameters and futile recanalization in patients with acute ischemic stroke undergoing mechanical thrombectomy

European Journal of Medical Research
Background Non-traditional lipid parameters are crucial biomarkers associated with outcomes of acute ischemic stroke (AIS). We aim to explore the relationship between non-traditional lipid parameters and futile recanalization (FR) following mechanical ...
Jia Duan, Jian Duan, Longyi Zheng, Shuang Tang, Shuang Xie, Wenli Xing, Ao Qian   +6 more
doaj   +1 more source

Low expression or hypermethylation of PLK2 might predict favorable prognosis for patients with glioblastoma multiforme [PDF]

PeerJ, 2019
Background As the most aggressive brain tumor, patients with glioblastoma multiforme (GBM) have a poor prognosis. Our purpose was to explore prognostic value of Polo-like kinase 2 (PLK2) in GBM, a member of the PLKs family. Methods The expression profile
Xiangping Xia, Fang Cao, Xiaolu Yuan, Qiang Zhang, Wei Chen, Yunhu Yu, Hua Xiao, Chong Han, Shengtao Yao   +8 more
doaj   +2 more sources

Concise review : increasing the validity of cerebrovascular disease models and experimental methods for translational stem cell research [PDF]

, 2017
Interspecies differences, anatomical and physiological aspects, as wells as simplified study designs contribute to an overestimation of treatment effects and limit the transferability of experimental results into clinical applications.
Boltze, Johannes, Jolkkonen, Jukka, Nitzsche, Björn, Nitzsche, Franziska, Pösel, Claudia, Wagner, Daniel-Christoph, Weise, Gesa   +6 more
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Prior Antithrombotic Therapy Is Associated With Cerebral Microbleeds in Ischemic Stroke Patients With Atrial Fibrillation and/or Rheumatic Heart Disease

Frontiers in Neurology, 2019
Background and purpose: Cerebral microbleeds (CMBs) could contribute to an increased risk of intracerebral hemorrhage in patients with antithrombotic therapy (antiplatelets or anticoagulants). Antithrombotic agents are commonly prescribed to the patients
Yajun Cheng, Junfeng Liu, Shuting Zhang, Jie Li, Chenchen Wei, Deren Wang, Jing Lin, Jing Lin, Yanan Wang, Bo Wu, Shihong Zhang, Ming Liu   +11 more
doaj   +1 more source

Immune and Clinical Features of CD96 Expression in Glioma by in silico Analysis

Frontiers in Bioengineering and Biotechnology, 2020
BackgroundImmune checkpoints target regulatory pathways in T cells that enhance antitumor immune responses and elicit durable clinical responses. As a novel immune checkpoint, CD96 is an attractive key target for cancer immunotherapy.
Qiang Zhang, Hua Zhong, Yinchun Fan, Qian Liu, Jiancheng Song, Shengtao Yao, Fang Cao   +6 more
doaj   +1 more source

Allostatic load predicts racial disparities in intracerebral hemorrhage cognitive outcomes

Scientific Reports, 2022
A large portion of stroke disparities remains unexplained, even after adjusting for demographic, comorbidity, and health care access variables. There is a critical need to close this knowledge gap by investigating novel factors that may contribute to ...
Jennifer Harris, Amelia Boehme, Luisa Chan, Harmon Moats, Rachelle Dugue, Chigozirim Izeogu, Marykay A. Pavol, Imama A. Naqvi, Olajide Williams, Randolph S. Marshall   +9 more
doaj   +1 more source

Cerebral hemodynamic characteristics of acute mountain sickness upon acute high-altitude exposure at 3,700 m in young Chinese men. [PDF]

, 2014
PURPOSE: We aimed at identifying the cerebral hemodynamic characteristics of acute mountain sickness (AMS). METHODS: Transcranial Doppler (TCD) sonography examinations were performed between 18 and 24 h after arrival at 3,700 m via plane from 500 m (n ...
Bian, Shi-Zhu, Chen, Jian-Fei, Huang, Lan, Jin, Jun, Li, Qian-Ning, Qin, Jun, Tang, Cai-Fa, Yu, Shi-Yong, Zhang, Ji-Hang   +8 more
core   +2 more sources

A comprehensive evaluation of the associations between 12 composite inflammatory indices and all-cause mortality after stroke: a multicohort study

Frontiers in Aging Neuroscience
BackgroundInflammation plays a critical role in post-stroke mortality. However, identification of robust and generalizable inflammatory biomarkers for post-stroke mortality remains a challenge.
Longyi Zheng, Rundong He, Shuang Tang, Jia Duan, Wenli Xing, Ao Qian   +5 more
doaj   +1 more source

Integration of Transcriptome Resequencing and Quantitative Proteomics Analyses of Collagenase VII-Induced Intracerebral Hemorrhage in Mice

Frontiers in Genetics, 2020
ObjectiveIntracerebral hemorrhage (ICH) is a subtype of stroke with high mortality and morbidity rates. Our aim was to comprehensively analyze transcriptome and proteome in an experimental ICH model.MethodsAll mice were divided into ICH model (n = 3) and
Fang Cao, Yu Guo, Qiang Zhang, Yinchun Fan, Qian Liu, Jiancheng Song, Hua Zhong, Shengtao Yao   +7 more
doaj   +1 more source

Assessing the effect of statins in lowering the risk of stroke and preventing cerebral ischemia in patients with hypercholesterolemia [PDF]

, 2017
Numerous analyses have explored the role of statins in reducing stroke incidence, reducing cerebral ischemia in hypercholesterolemic patients, and preventing ischemic stroke.
AlSulaiman, Wafa
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