Results 21 to 30 of about 458,125 (267)

Genetics of Cerebrovascular Disease [PDF]

Stroke, 2004
Stroke is a complex disease, with both genetic and environmental factors having a role in its pathogenesis. A review of past studies shows some evidence of genetic influences in the development of stroke. This is supported by studies of cardiovascular disease, which indicate major genetic influences at several levels including the development of risk ...
openaire   +3 more sources

Cerebrovascular disease and stroke [PDF]

Archives of Disease in Childhood, 2008
Stroke and cerebrovascular disorders are important causes of morbidity and mortality in children; they are already amongst the top 10 causes of childhood death and are probably increasing in prevalence. Acute treatment of stroke syndromes in adults is now evidence based.
Pappachan, John, Kirkham, Fenella
openaire   +4 more sources

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

A novel cuproptosis-associated LncRNA model predicting prognostic and immunotherapy response for glioma

Discover Oncology
Recent studies have identified cuproptosis as a novel form of regulated cell death (RCD), and long non-coding RNAs (lncRNAs) have been implicated in glioma progression and prognosis.
Bo Lei, Ao zhan, Guoliang You, Honggang Wu, Shu Chen, Daobao Zhang, Zhiye Liu, Niandong Zheng   +7 more
doaj   +1 more source

Current understanding of macrophages in intracranial aneurysm: relevant etiological manifestations, signaling modulation and therapeutic strategies

Frontiers in Immunology
Macrophages activation and inflammatory response play crucial roles in intracranial aneurysm (IA) formation and progression. The outcome of ruptured IA is considerably poor, and the mechanisms that trigger IA progression and rupture remain to be ...
Jian Duan, Qijie Zhao, Qijie Zhao, Zeyuan He, Shuang Tang, Jia Duan, Wenli Xing   +6 more
doaj   +1 more source

Association between urinary caffeine and caffeine metabolites and stroke in American adults: a cross-sectional study from the NHANES, 2009–2014

Scientific Reports, 2023
This study investigates the potential correlation between urinary caffeine levels and the occurrence of stroke, a serious cerebrovascular disease that can lead to disability or death.
Jinming Fan, Yajun Yuan, Xiaoting Zhang, Wenhan Li, Wuqin Ma, Wenhao Wang, Jinyan Gu, Bin Zhou   +7 more
doaj   +1 more source

New device multisegment Mechanical Thrombectomy System for endovascular treatment in acute ischaemic stroke: study protocol for a prospective, multicentre, randomised controlled trial

BMJ Open, 2022
Introduction Endovascular treatment is the standard of care for acute large vessel occlusion (LVO) in the anterior circulation. However, successful complete recanalisation is considerably difficult when the vessels are severely tortuous. At the bend, the
Tengfei Zhou, Yingkun He, Tianxiao Li, Zhaoshuo Li, Hailong Zhong   +4 more
doaj   +1 more source

Dementia and Cerebrovascular Disease [PDF]

Mayo Clinic Proceedings, 2006
Cerebrovascular disease is an important cause of cognitive Impairment and dementia in elderly patients. This review highlights the challenges involved in examining the role of cerebrovascular disease In dementia, areas in which consensus is emerging, and an operational framework for clinicians. Two important challenges exist.
openaire   +2 more sources

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Association between non-traditional lipid parameters and futile recanalization in patients with acute ischemic stroke undergoing mechanical thrombectomy

European Journal of Medical Research
Background Non-traditional lipid parameters are crucial biomarkers associated with outcomes of acute ischemic stroke (AIS). We aim to explore the relationship between non-traditional lipid parameters and futile recanalization (FR) following mechanical ...
Jia Duan, Jian Duan, Longyi Zheng, Shuang Tang, Shuang Xie, Wenli Xing, Ao Qian   +6 more
doaj   +1 more source