Results 41 to 50 of about 483,075 (169)

Immune and Clinical Features of CD96 Expression in Glioma by in silico Analysis

Frontiers in Bioengineering and Biotechnology, 2020
BackgroundImmune checkpoints target regulatory pathways in T cells that enhance antitumor immune responses and elicit durable clinical responses. As a novel immune checkpoint, CD96 is an attractive key target for cancer immunotherapy.
Qiang Zhang, Hua Zhong, Yinchun Fan, Qian Liu, Jiancheng Song, Shengtao Yao, Fang Cao   +6 more
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Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury

Nature Communications, 2016
Matrix metalloproteinases (MMPs) released from infiltrating immune cells are a major contributor to blood-brain barrier (BBB) breakdown following stroke.
Yejie Shi, Lili Zhang, Hongjian Pu, Leilei Mao, Xiaoming Hu, Xiaoyan Jiang, Na Xu, R. Anne Stetler, Feng Zhang, Xiangrong Liu, Rehana K. Leak, Richard F. Keep, Xunming Ji, Jun Chen   +13 more
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Associations of Different Inflammatory Markers with Neurological Deficit Severity and Short-Term Prognosis in Young Patients with Ischemic Stroke

Journal of Inflammation Research
Huimin Wu,1,* Anxing Huang,2,* Keke Jiang,2,* Xiuping Wei,1 Zhi Ma,1 Haibo Jiang,1 Lili Xu,1 Wenya Lan,1 Mingyang Du,1 Hui Cao,1 Shanshan Chen,2 Xingjian Lin,2 Feng Qiu11Department of Cerebrovascular Disease Center, Affiliated ...
Wu H, Huang A, Jiang K, Wei X, Ma Z, Jiang H, Xu L, Lan W, Du M, Cao H, Chen S, Lin X, Qiu F   +12 more
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Associations between inflammatory-lipid indices and clinical outcomes in ischemic stroke patients treated with mechanical thrombectomy

Frontiers in Aging Neuroscience
PurposeInflammation and dyslipidemia are critical in post-stroke prognosis. We conducted a comprehensive analysis of six common inflammatory-lipid indices to evaluate the associations between these indices and four clinical outcomes after mechanical ...
Ao Qian, Jia Duan, Wenli Xing, Longyi Zheng, Shuang Tang   +4 more
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NAMPT inhibition induces ferroptosis via mitochondrial metabolic reprogramming to enhance tumour immunogenicity in glioblastoma

Frontiers in Immunology
BackgroundFerroptosis has recently been recognised as an immunogenic form of regulated cell death. Nicotinamide phosphoribosyltransferase (NAMPT), a key enzyme in the NAD+ salvage pathway, is highly expressed in glioblastoma and represents a promising ...
Dongxu Zhao, Lin Duan, Hang Ren, Hang Zhang, Menghui Zhang, Zhuohang Liu, Hailan Wang, Wenxuan Lu, Wenhan Shi, Qingwang Hou, Tianxiao Li, Ming Li   +11 more
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The Impact of Meticulous Nursing on Self-Care Ability Within Two Weeks Postoperatively in Patients with Acute Stroke

Journal of Multidisciplinary Healthcare
Yan Yang,1,2 Xiuxia Shi,3 Yuanzheng Zhang,4 Xinmin Song,1 Xiaojie Zhang1 1Cerebrovascular Disease Treatment Center, Tianjin Fifth Central Hospital, Tianjin, People’s Republic of China; 2The Fifth Central Clinical College of Tianjin Medical University ...
Yang Y, Shi X, Zhang Y, Song X, Zhang X
doaj  

Association Analysis Between Ischemic Stroke Risk Single Nucleotide Polymorphisms and Alzheimer’s Disease

Bioengineering
Alzheimer’s disease (AD) and ischemic stroke (IS) are prevalent neurological disorders that frequently co-occur in the same individuals. Recent studies have demonstrated that AD and IS share several common risk factors and pathogenic elements, including ...
Wei Dong, Wei Wang, Mingxuan Li
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uPAR and cFn as candidate protein biomarkers for identifying low response to rtPA in acute ischemic stroke

European Journal of Medical Research
Background Recombinant tissue plasminogen activator (rtPA) remains the main therapeutic for acute ischemic stroke (AIS). In clinical practice, the patients with AIS presenting low response to rtPA is commonly observed. Cognizant that the endothelial cell
Yilin Wang, Yuyou Huang, Fangfang Li, Ziping Han, Zhenhong Yang, Liyuan Zhong, Lingzhi Li, Haiping Zhao, Junfen Fan, Yangmin Zheng, Cesario Borlongan, Yumin Luo   +11 more
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Microsurgical treatment of intracranial dural arteriovenous fistula and prognosis analysis

Interdisciplinary Neurosurgery
Objective: To summarize and analyze the curative effect of 46 patients with intracranial dural arteriovenous fistula (DAVF) treated by microsurgery, explore the prognostic factors of DAVF, and summarize the skills and experience of surgical treatment ...
Lijiu Chen, Zhiqiang Yu, Cheng Qiu, Guangxu Zhang, Jinbing Zhao, Shengxue He   +5 more
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Predictors of Mortality in Posterior Circulation Ischemic Stroke

Medicina
Background and Objectives: Posterior circulation ischemic stroke (PCIS) is a life-threatening disease with a poor prognosis. It has nonspecific symptoms. It is very difficult to diagnose.
Sanja Rsovac Ivanović, Filip Vitošević, Damljan Bogićević, Dejana Senji, Ljubica Nikčević Krivokapić, Marjana Vukićević, Nemanja Rančić, Dragan Mašulović, Biljana Georgievski-Brkić   +8 more
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