Results 1 to 10 of about 370,564 (120)

Body roundness index improves the predictive value of cardiovascular disease risk in hypertensive patients with obstructive sleep apnea: a cohort study

open access: yesClinical and Experimental Hypertension, 2023
Background Obesity, especially visceral obesity, plays an important role in the progression of cardiovascular disease (CVD). The body roundness index (BRI) is a new measure of obesity that is considered to reflect visceral obesity more comprehensively ...
Xintian Cai   +8 more
doaj   +1 more source

Exercise Preconditioning Ameliorates Cognitive Impairment in Mice with Ischemic Stroke by Alleviating Inflammation and Modulating Gut Microbiota

open access: yesMediators of Inflammation, 2022
Several studies have demonstrated that exercise preconditioning is an effective means of alleviating poststroke cognitive impairment (PSCI). Mechanisms of regulating cognitive function have not been fully elucidated. Herein, the present study is aimed at
Heng Lv   +8 more
doaj   +1 more source

Progranulin improves neural development via the PI3K/Akt/GSK-3β pathway in the cerebellum of a VPA-induced rat model of ASD

open access: yesTranslational Psychiatry, 2022
Autism spectrum disorder (ASD) is a neurodevelopmental disease featuring social interaction deficits and repetitive/stereotyped behaviours; the prevalence of this disorder has continuously increased.
Lili Wang   +12 more
doaj   +1 more source

Matrix Metalloproteinase-9 as an Important Contributor to the Pathophysiology of Depression

open access: yesFrontiers in Neurology, 2022
Matrix metalloproteinases (MMPs) are physiologically expressed in the central nervous system in neurons, astrocytes and microglia, and their aberrant elevation contributes to a number of diseases. Amongst the MMP members, MMP−9 has generated considerable
Hongmin Li   +15 more
doaj   +1 more source

Neutrophilic noncoding RNAs predict outcomes of acute ischemic stroke patients treated with recombinant tissue plasminogen activator

open access: yesFrontiers in Pharmacology, 2022
There’s no evidence demonstrating the association between noncoding RNAs levels before IV recombinant tissue plasminogen activator (rtPA) administration and the outcomes of acute ischemic stroke (AIS).
Ziping Han   +20 more
doaj   +1 more source

Association between low-density cholesterol change and outcomes in acute ischemic stroke patients who underwent reperfusion therapy

open access: yesBMC Neurology, 2021
Background Low-density lipoprotein cholesterol (LDL-C) can increase cardiovascular risk. However, the association between LDL-C change and functional outcomes in acute ischemic stroke (AIS) patients who underwent reperfusion therapy remains unclear ...
Ting Cui   +9 more
doaj   +1 more source

Prognostic significance of plasma IL-2 and sIL-2Rα in patients with first-ever ischaemic stroke

open access: yesJournal of Neuroinflammation, 2020
Background An imbalance between circulating neuroprotective and neurotoxic T cell subsets leads to poor prognosis in acute ischaemic stroke (AIS). Preclinical studies have indicated that the soluble form of the interleukin-2 receptor α (sIL-2Rα)-IL-2 ...
Haiping Zhao   +12 more
doaj   +1 more source

Modes of Brain Cell Death Following Intracerebral Hemorrhage

open access: yesFrontiers in Cellular Neuroscience, 2022
Intracerebral hemorrhage (ICH) is a devastating form of stroke with high rates of mortality and morbidity. It induces cell death that is responsible for neurological deficits postinjury.
Yan Zhang   +14 more
doaj   +1 more source

Hypoplasia of the ipsilateral internal jugular vein is associated with worse outcome in acute anterior circulation stroke [PDF]

open access: yesVojnosanitetski Pregled, 2019
Background/Aim. Disruption of cerebral venous blood drainage leads to cerebral venous congestion, an increase in intracranial pressure and decrease of the cerebral perfusion pressure.
Vukičević Marjana   +5 more
doaj   +1 more source

Efficacy of pipeline embolization device vs. traditional coils in embolization of intracranial aneurysms: A systematic review and meta-analysis

open access: yesFrontiers in Neurology, 2022
IntroductionIn recent years, the Pipeline embolization device (PED) has been widely used in the embolization of intracranial aneurysms, but there are some inconsistent findings on whether its efficacy and safety are superior to those of traditional coils
Wei Li   +19 more
doaj   +1 more source

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