Results 161 to 170 of about 370,713 (268)

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

Interdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi, Min Chen, Yisheng Chen, MengYao Li, Jiale Ma, Zuozhen Yin, Li Wu, YangBao Miao, Zemin Ou, Ke Wu, Zhijie Xu, Lizhi Li, Shaocong Zhao, Shiwei He, Bin Huang, Guanwen He, Guanghui Wu, John H. Zhang, Liang Shi   +18 more
wiley   +1 more source

The multi-target protective effects of quercetin in cerebrovascular diseases: a dietary strategy for endothelial repair and neuroprotection. [PDF]

Front Nutr
Lu T, Gao J, Zhu P, Cao R, Ye K.
europepmc   +1 more source

Dopamine Transporter Imaging‐Based Radiomics for Predicting 4‐Year Motor Progression (Unified Parkinson's Disease Rating Scale Part III) in Parkinson's Disease

iRADIOLOGY, EarlyView.
Magnetic resonance imaging (MRI)‐guided dopamine transporter (DAT) radiomics combined with machine learning showed promising performance for predicting 4‐year motor progression in Parkinson's disease. Ensemble voting fusion markedly improved discrimination compared with individual base models, with stable predictive features mainly derived from ...
Xiaoxuan Fan, Yanghan Chen, Junfeng Lin, Zenwen Han, Jianqiang Ye, Lili Lin, Hong Zhang, Ang Li, Han Jiang   +8 more
wiley   +1 more source

Impact of severe infections on the risk of acute cardiovascular and cerebrovascular diseases: A prospective cohort study. [PDF]

Am J Prev Cardiol
Tang S, Jiang Y, Wu Y, Su X, Wang S, Chen R, Zhao G, Xu W, Liu X, Zhang R, Zhang T, Chen X, Jiang Y, Suo C.   +13 more
europepmc   +1 more source

Advances in Fluorescent Probes Targeting Senescence‐Associated β‐Galactosidase for Senescence Imaging

iRADIOLOGY, EarlyView.
Senescence‐associated β‐galactosidase fluorescent probes enable sensitive visualization of cellular senescence through turn‐on, ratiometric, aggregation‐induced emission‐active, and nanoprobe strategies. ABSTRACT Aging is a systemic biological process that spans multiple levels, including molecules, cells, tissues, and organs.
Jiahui Wang, Jun Wang, Shu Gao, Kun Qian, Qihang Ding, Zhen Cheng   +5 more
wiley   +1 more source

Causal Associations Between Human Blood Metabolites and Cardio-Cerebrovascular Diseases: A Mendelian Randomisation Study. [PDF]

Clin Appl Thromb Hemost
Zhang H, Xie J, He C, Hu H, Zhai C, Qian G, Mao M.   +6 more
europepmc   +1 more source

Age‐Associated Variations in Complete Blood Cell Count Parameters and Derived Indices Among Community‐Dwelling Chinese Older Adults

Journal of Clinical Laboratory Analysis, EarlyView.
This cross‐sectional study analyzed data from 9331 participants aged 24–97 to characterize age‐ and sex‐related physiological trajectories of complete blood cell count (CBC) parameters and derived inflammatory indices. Key findings encompassed age‐related declines in red blood cell and platelet counts, elevations in RDW‐CV indices and monocyte ...
Xiangyi Ma, Na Liu, Xiang Wu, Qiudan Chen, Xiaotong Chen, Qingyu Zhou, Shuying Chen, Yong Lin, Xuefeng Wang   +8 more
wiley   +1 more source

Perfusion Territory Shifts in Cerebrovascular Diseases Measured by Super-Selective Arterial Spin Labeling. [PDF]

J Neuroimaging
Hoffmann G, Reichert M, Göttler J, Helle M, Schmitzer L, Petzsche MH, Zimmer C, Preibisch C, Kallmayer M, Kreiser K, Sollmann N, Liebl H, Kaczmarz S.   +12 more
europepmc   +1 more source

Transcranial Color‐Coded Duplex Sonography in Large‐Vessel Vasculitis Compatible With Takayasu Arteritis Presenting Intracranial Involvement and Vertebrobasilar Dolichoectasia: A Case Report

Journal of Clinical Ultrasound, EarlyView.
This case illustrates sequential intracranial occlusions in large‐vessel vasculitis compatible with Takayasu arteritis preserving perfusion through robust collateral pathways. Transcranial color‐coded duplex sonography identified characteristic blunted flow patterns and focal turbulence, underscoring its value in detecting hemodynamic compromise beyond
Maria Júnia Lira e Silva, Jordana Gaudie Gurian, Isabella Mesquita Venâncio, Eva Carolina Rocha, Gisele Sampaio Silva   +4 more
wiley   +1 more source