Results 71 to 80 of about 248,312 (241)

Effect of Stress Hyperglycemia on Neurological Deficit and Mortality in the Acute Ischemic Stroke People With and Without Diabetes

Frontiers in Neurology, 2020
Objective: To determine the relationship between stress hyperglycemia and prognosis of acute ischemic stroke people with and without diabetes.Methods: A subgroup of 8,622 acute ischemic stroke people with baseline levels of fasting blood glucose and ...
Jiejie Li, Jiejie Li, Jiejie Li, Jiejie Li, Kehua Quan, Kehua Quan, Kehua Quan, Kehua Quan, Yilong Wang, Yilong Wang, Yilong Wang, Yilong Wang, Xingquan Zhao, Xingquan Zhao, Xingquan Zhao, Xingquan Zhao, Zixiao Li, Zixiao Li, Zixiao Li, Zixiao Li, Yuesong Pan, Yuesong Pan, Yuesong Pan, Yuesong Pan, Hao Li, Hao Li, Hao Li, Hao Li, Liping Liu, Liping Liu, Liping Liu, Liping Liu, Yongjun Wang, Yongjun Wang, Yongjun Wang, Yongjun Wang   +35 more
doaj   +1 more source

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

Advanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan, Yuanxiu Wei, Yiting Wu, Xinyue Su, Gangling Wang, Sisi Yang, Ziliang Ye, Yanjun Zhang, Hao Xiang, Yu Huang, Yiwei Zhang, Yuanyuan Zhang, Xianhui Qin   +12 more
wiley   +1 more source

Risk Profile of Ischemic Stroke Caused by Small-Artery Occlusion vs. Deep Intracerebral Hemorrhage

Frontiers in Neurology, 2019
Background: Small-artery occlusion (SAO) subtype accounts for a quarter of the cases of ischemic stroke and is mainly caused by pathological changes in cerebral small vessels, which also involve in deep intracerebral hemorrhage (dICH).
Zimo Chen, Zimo Chen, Zimo Chen, Zimo Chen, Jinglin Mo, Jinglin Mo, Jinglin Mo, Jinglin Mo, Jie Xu, Jie Xu, Jie Xu, Jie Xu, Haiqiang Qin, Haiqiang Qin, Haiqiang Qin, Haiqiang Qin, Huaguang Zheng, Huaguang Zheng, Huaguang Zheng, Huaguang Zheng, Yuesong Pan, Yuesong Pan, Yuesong Pan, Yuesong Pan, Xia Meng, Xia Meng, Xia Meng, Xia Meng, Jing Jing, Jing Jing, Jing Jing, Jing Jing, Xianglong Xiang, Xianglong Xiang, Xianglong Xiang, Yongjun Wang, Yongjun Wang, Yongjun Wang, Yongjun Wang   +38 more
doaj   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Endothelial Cell‐Based Vascular Bandages for Blood–Brain Barrier Repair and Targeted siRNA Delivery

Advanced Science, EarlyView.
mECs restore blood–brain barrier function after cerebral ischemia–reperfusion by simultaneously targeting, supporting, and regulating the damaged vasculature. mECs home to injured cerebral vessels through interactions with highly expressed VLA‐4, reinforce endothelial integrity by forming new junctions, and, upon OGD‐SN treatment, acquire enhanced ...
Yaosheng Li, Yunfei Dong, Yaode He, Juanjuan Zheng, Hui Liu, Lu Li, Xiaoxu Hao, Yanli Zhao, Zefeng Yang, Yuankai Sun, Zhiwei Du, Bo Zhao, Weihang Zhou, Honghui Wu, Tianyuan Zhang, Jiahe Wu, Xiangrui Liu, Xianzhen Yin, Zhicai Chen, Rui Xue, Min Lou, Zhen Gu, Xinchi Jiang, Jianqing Gao   +23 more
wiley   +1 more source

Data‐Driven Feedback Identifies Focused Ultrasound Exposure Regimens for Improved Nanotheranostic Targeting of the Brain

Advanced Science, EarlyView.
ABSTRACT The blood‐brain barrier (BBB) renders the delivery of nanomedicine in the brain ineffective and the detection of circulating disease‐related DNA from the brain unreliable. Here, we demonstrate that microbubble‐enhanced focused ultrasound (MB‐FUS) mediated BBB opening, supported by large‐data models predict sonication regimens for safe and ...
Hohyun Lee, Victor Menezes, Shiqin Zeng, Chulyong Kim, Cynthia M. Baseman, Jae Hyun Kim, Samhita Padmanabhan, Pranav Premdas, Naima Djeddar, Anton Bryksin, Nikhil Pandey, Pavlos Anastasiadis, Anthony J. Kim, Tobey J. MacDonald, Chetan Bettegowda, Graeme F. Woodworth, Felix J. Herrmann, Costas Arvanitis   +17 more
wiley   +1 more source

Platelet Count Predicts Adverse Clinical Outcomes After Ischemic Stroke or TIA: Subgroup Analysis of CNSR II

Frontiers in Neurology, 2019
Background: The clinical significance of platelet count (PC) for ischemic cerebrovascular disease is not well-established and further risk stratification according to baseline PC within normal range has not been reported before.
Ming Yang, Ming Yang, Ming Yang, Ming Yang, Yuesong Pan, Yuesong Pan, Yuesong Pan, Yuesong Pan, Zixiao Li, Zixiao Li, Zixiao Li, Zixiao Li, Hongyi Yan, Hongyi Yan, Hongyi Yan, Hongyi Yan, Xingquan Zhao, Xingquan Zhao, Xingquan Zhao, Xingquan Zhao, Liping Liu, Liping Liu, Liping Liu, Liping Liu, Jing Jing, Jing Jing, Jing Jing, Jing Jing, Xia Meng, Xia Meng, Xia Meng, Xia Meng, Yilong Wang, Yilong Wang, Yilong Wang, Yilong Wang, Yongjun Wang, Yongjun Wang, Yongjun Wang, Yongjun Wang   +39 more
doaj   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Comparative analysis of cognitive functions in patients with episodic and chronic tension-type headache combined with psychovegetative syndrome and cerebrovascular disorders

Бюллетень сибирской медицины, 2008
The purpose of the study was to compare cognitive functions in patients with episodic tension-type headache (EpTTH) and chronic tension-type headache (ChTTH).EpTTH was diagnosed in 34 patients in which it combined with psychovegetative syndrome in 17 ...
Ye. A. Yegorova, V. N. Grigoriyeva
doaj   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source