Results 191 to 200 of about 51,296 (302)

Inhibition of Ornithine Decarboxylase 1 Mitigates Denervation‐Induced Muscle Atrophy by Suppressing Proteolysis and Preserving Muscle Stem Cell Homeostasis

Cell Proliferation, EarlyView.
Polyamine metabolism is innervation responsive and involved in denervation‐induced muscle atrophy. Inhibition of polyamine metabolism attenuates muscle atrophy by restraining proteolysis and preserving MuSCs homeostasis. Denervation‐induced activation of FAP‐derived FGF7 drives premature MuSCs activation, while DFMO suppresses this paracrine cue to ...
Mingming Zhang, Feifan Chang, Siliang Ge, Fuming Cao, Pincong Fu, Haobo Zhang, Ming Chen, Yi Li, Peifu Tang, Pengbin Yin   +9 more
wiley   +1 more source

The burden of COVID‐19 in hospitalized people with diabetes mellitus in Brazil: Insights from four years of the pandemic

Diabetic Medicine, EarlyView.
Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo, Bianca Aparecida Siqueira, Luiz Felipe Azevedo Marques, Lucas Silva Mello, Fernando Augusto Lima Marson   +4 more
wiley   +1 more source

End points for sickle cell disease clinical trials: Patient-reported outcomes, pain, and the brain [PDF]

, 2019
al., et, Farrell, Ann T., King, Allison A.   +2 more
core   +1 more source

Association Between Gas-Free Cerebrovascular Reactivity (CVR) and Cognitive Function in Older Adults With a High Risk for Vascular Dementia. [PDF]

J Magn Reson Imaging
Badrzadeh F, Karimigharighi E, Liang H, Chan A, Chang L, Liu P.   +5 more
europepmc   +1 more source

Comparative Predictive Value of Three Visceral Adiposity Indices for Cardiovascular Disease: A 17.5‐Year Korean Cohort Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Cardiovascular diseases (CVD) are the leading cause of death worldwide, with excess visceral adipose tissue (VAT) being identified as an independent indicator of poor cardiovascular outcomes. We examined the association between three indices of VAT, namely, metabolic score for visceral fat (METS‐VF), visceral adiposity index (VAI), and ...
A‐Ra Cho, Seok‐Jae Heo, Taehwa Han, Yu‐Jin Kwon   +3 more
wiley   +1 more source

CEREBROVASCULAR REACTIVITY IN CEREBRAL AMYLOID ANGIOPATHY

Cerebral Circulation - Cognition and Behavior
Andrew E. Beaudin, Cheryl R. McCreary, Erin L. Mazerolle, Myrlene Gee, Breni Sharma, Arsenije Subotic, Angela Zwiers, Emily Cox, Krista Nelles, Anna Charlton, Richard Frayne, Zahinoor Ismail, Christian Beaulieu, Glen C. Jickling, Richard Camicioli, G. Bruce Pike, Eric E. Smith   +16 more
doaj   +1 more source

Cerebrovascular Reactivity and Cerebral Ischemia During Chronic Hemodialysis. [PDF]

Hemodial Int
Wolfgram DF, Grassl I, Seigworth C, Widlansky ME, Gao Y.   +4 more
europepmc   +1 more source

Prediabetes, Malignant Ventricular Hypertrophy and Stroke: The SPRINT Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Prediabetes and left ventricular hypertrophy (LVH) are common risk factors in adults with hypertension. Whether their coexistence, particularly in the presence of subclinical myocardial injury or stress (malignant LVH), confers a heightened stroke risk is unknown.
Arnaud D. Kaze, Stephen P. Juraschek, Jordana B. Cohen, Siddharth Singh, Chiadi E. Ndumele, Christie M. Ballantyne, Jarrett D. Berry, Justin B. Echouffo‐Tcheugui   +7 more
wiley   +1 more source

NIRS frequency analysis to evaluate cerebrovascular reactivity after acute brain injury. [PDF]

Neurophotonics
Bicciato G, de Trizio I, Brandi G, Willms JF, Keller E.   +4 more
europepmc   +1 more source