Results 181 to 190 of about 445,834 (292)

Associations of cannabis use, tobacco use and co‐use with brain volume: A systematic review and meta‐analysis

open access: yesAddiction, EarlyView.
Abstract Background and aims Cannabis is the most widely used illicit drug worldwide and is often co‐used with tobacco, the leading cause of preventable death. Although cannabis and tobacco have distinct neurobiological actions, their associations with brain volumes are unclear.
Katherine Sawyer   +16 more
wiley   +1 more source

Alcohol consumption and cognitive function: A systematic review and dose–response meta‐analysis of 20 cohort studies

open access: yesAddiction, EarlyView.
Abstract Background and aims Amid ongoing debate on whether low‐to‐moderate alcohol consumption reduces cardiovascular risk, studies examining the association between alcohol consumption and cognitive function have reported inconsistent results. To quantitatively assess this association, we conducted a dose–response meta‐analysis of cohort studies ...
Sooyeun Choi, Youjin Je
wiley   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

open access: yesAndrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Heart‐Rate Variability and Its Role in Non‐Cardiac Surgery Perioperative Care: Scoping Review

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Background Heart rate variability (HRV) is a non‐invasive method of assessing autonomic function. Those with autonomic dysfunction may be at heightened risk of peri‐operative complications due to sympatho‐parasympathetic imbalance. This review summarises the clinical applications of HRV, approaches to how it is measured, and its role in ...
Reuben Veysey‐Smith   +3 more
wiley   +1 more source

SURGELLA: A Scoping Review of Impella‐Assisted Hemodynamic Support in High‐Risk Non‐Cardiac Surgery

open access: yesArtificial Organs, EarlyView.
In selected patients with severe LV dysfunction, Impella‐supported non‐cardiac surgery may provide a temporary hemodynamic bridge to otherwise prohibitive procedures. Published evidence remains limited to a small number of highly selected cases, supporting technical feasibility rather than comparative benefit or generalizable safety.
Hussein Elghazaly   +6 more
wiley   +1 more source

CEREBROVASCULAR REACTIVITY IN CEREBRAL AMYLOID ANGIOPATHY

open access: yesCerebral Circulation - Cognition and Behavior
Andrew E. Beaudin   +16 more
doaj   +1 more source

Impact of Respiratory Support Strategies on CO2 Variability During Therapeutic Hypothermia in Neonates With Asphyxia: Data From the German Hypothermia Registry

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To evaluate associations between respiratory support strategies, partial pressure of carbon dioxide (pCO2) variability and oxygen exposure in neonates with hypoxic–ischaemic encephalopathy (HIE) undergoing therapeutic hypothermia (TH). Methods This retrospective multicentre study used data from the German Hypothermia Registry, including ...
Sebiha Demir   +93 more
wiley   +1 more source

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