Results 161 to 170 of about 51,296 (302)

How Can We Personalize the Delivery of Onabotulinumtoxin‐A for Patients With Neurogenic Lower Urinary Tract Dysfunction?

Neurourology and Urodynamics, EarlyView.
ABSTRACT Background & Aims Neurogenic lower urinary tract dysfunction (NLUTD) can produce bothersome urinary symptoms, impact quality of life, and in some cases, lead to deterioration of upper urinary tract function. Intradetrusor injection of onabotulinumtoxin‐A (BoNT‐A) is approved for NLUTD in patients who have an inadequate response to or ...
Shirley L. Wang, William I. Jaffe, Ariana L. Smith   +2 more
wiley   +1 more source

Insult to Injury: Dialysis-Induced Cerebrovascular Reactivity and Cognitive Impairment. [PDF]

Kidney360
Vanderlinden J, Tamasi T, Dorie J, McIntyre C.   +3 more
europepmc   +1 more source

Gene expression profiling to identify microvascular changes in Alzheimer's disease mouse models [PDF]

, 2008
Ceuterick, Chantal, Cuijt, Ivy, Deforce, Dieter, Jucker, Mathias, Kumar-Singh, Samir, McGowan, Eileen, Peeters, Edith, Pereson, Sandra, Van Broeck, Bianca, Van Broeckhoven, Christine, Vandewoestyne, Mado   +10 more
core   +2 more sources

Modeling of Disease Progression of Type 2 Diabetes Using Real‐World Data: Quantifying Competing Risks of Morbidity and Mortality

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 606-615, March 2025.
ABSTRACT Type 2 diabetes (T2D) is a progressive metabolic disorder that could be an underlying cause of long‐term complications that increase mortality. The assessment of the probability of such events could be essential for mortality risk management. This work aimed to establish a framework for risk predictions of macrovascular complications (MVC) and
Hanna Kunina, Stefan Franzén, Maria C. Kjellsson   +2 more
wiley   +1 more source

Neurovascular coupling and cerebrovascular reactivity: physiology, lifespan development, pathophysiology, and clinical relevance. [PDF]

Front Physiol
Khartabil Z, Kala D, Prysiazhniuk Y, Otáhal J.   +3 more
europepmc   +1 more source

Impact of biological/targeted versus conventional synthetic disease‐modifying antirheumatic drugs on patient‐reported outcomes in rheumatoid arthritis

Rheumatology &Autoimmunity, EarlyView.
Patient‐reported outcomes (PROs) were compared among rheumatoid arthritis patients who maintained low disease activity or remission for at least 6 months based on the disease‐modifying antirheumatic drug (DMARD)administered. Even with comparable disease activity, methotrexate (MTX) group, biological/targeted synthetic DMARDs (b/tsDMARDs), particularly ...
Masafumi Sugiyama, Saki Okuda‐Tsuchimoto, Takashi tsuchimoto, Koji Kinoshita, Itaru Matsumura   +4 more
wiley   +1 more source

POLG‐Related Parkinsonism with Good Response to Deep Brain Stimulation

Movement Disorders Clinical Practice, EarlyView.
Evdokia Efthymiou, Fabian Büchele, Sujitha Mahendran, Lennart Stieglitz, Bettina Balint   +4 more
wiley   +1 more source

Association between sleep duration and cognitive function and emotional disorders in middle‐aged and elderly patients with cerebral small vessel disease

Sleep Research, EarlyView.
Abstract Objectives To investigate the association between the sleep duration with cognitive impairment in middle‐aged and elderly patients with cerebral small vessel disease (CSVD). Methods This cross‐sectional study enrolled hospitalized patients aged ≥55 years diagnosed with CSVD between November 2021 and August 2023.
Chunmei Long, Yunying Wu, Sha Wang, Ziwei Gong, Ye Wang   +4 more
wiley   +1 more source

The Relationship Between Hippocampal Cerebrovascular Reactivity and Brain Structure in Older Age. [PDF]

Hum Brain Mapp
Wang C, Jobbins L, Reid G, Hobden G, Patel R, Mackay CE, Ebmeier KP, Pinto J, Bulte D, Kivimäki M, Singh-Manoux A, Suri S.   +11 more
europepmc   +1 more source

Brain Pericytes and Wnt/β‐Catenin Signaling Induce Functional Blood–Brain Barrier Phenotype in Human iPSC‐Derived Model

Small Methods, EarlyView.
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto, Nine R. Kok, Philipp C. Hauger, Manon Karsten‐van Diepen, Michael de Kok, Nanne J. Paauw, Susanne M. A. van der Pol, Joline P. Nugteren‐Boogaard, Peter L. Hordijk, Stephanie D. Beekhuis‐Hoekstra, Susan Gibbs, Nienke M. de Wit, Helga E. de Vries   +12 more
wiley   +1 more source