Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Nii Kandis (Knowing Myself): Finding a Sacred Home at Anishnawbe Health Toronto Through Spirit-Based Healing. [PDF]
Reeves A +3 more
europepmc +1 more source
Mr. Brunner's ceremonial address on the 25th anniversary of the Joint Committee for the Harmonization of Working Conditions in the Coal-Mining Industry. Saarbrucken, 19 October 1979 [PDF]
Brunner, Guido.
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Earliest evidence of rice cultivation in Remote Oceania: Ritual use by the first islanders in the Marianas 3500 years ago. [PDF]
Carson MT +5 more
europepmc +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
"<i>Warmi urquy"</i>: marriage proposals and gender hierarchy in the Peruvian Andes. [PDF]
Gutiérrez-Gómez E +5 more
europepmc +1 more source
Arguments for the policy of ceremonial uniformity in the Church of England in the 1630s.
Aleksandra Stanislavovna Levchenko
openalex +1 more source

