Results 31 to 40 of about 23,377 (222)

Metabolite and lipoprotein profiles reveal sex-related oxidative stress imbalance in de novo drug-naive Parkinson’s disease patients

npj Parkinson's Disease, 2022
Parkinson’s disease (PD) is the neurological disorder showing the greatest rise in prevalence from 1990 to 2016. Despite clinical definition criteria and a tremendous effort to develop objective biomarkers, precise diagnosis of PD is still unavailable at
Gaia Meoni, Leonardo Tenori, Sebastian Schade, Cristina Licari, Chiara Pirazzini, Maria Giulia Bacalini, Paolo Garagnani, Paola Turano, PROPAG-AGEING Consortium, Claudia Trenkwalder, Claudio Franceschi, Brit Mollenhauer, Claudio Luchinat   +12 more
doaj   +1 more source

Diatom triacylglycerol metabolism: from carbon fixation to lipid droplet degradation. [PDF]

Biol Rev Camb Philos Soc
ABSTRACT Diatoms are a prominent microalgae family that has attracted interest for its production of molecules of biotechnological interest. Their fatty acid profile is rich in health‐beneficial omega‐3 eicosapentaenoic acid (EPA). Furthermore, under nutrient‐deprived conditions, many diatom species, notably Phaeodactylum tricornutum, Thalassiosira ...
Murison V, Hérault J, Marchand J, Ulmann L.   +3 more
europepmc   +2 more sources

Functional study of Phaeodactylum tricornutum Seipin highlights specificities of lipid droplets biogenesis in diatoms. [PDF]

New Phytol
Summary Diatoms are a major phylum of microalgae, playing crucial ecological roles. They derive from secondary endosymbiosis, leading to a complex intracellular architecture. Their ability to store oil in lipid droplets (LDs) upon unfavourable conditions has raised interest for applications, in particular biofuels, yet Lipid Droplet (LD) biogenesis ...
Le Moigne D, Carletti M, Amari C, Bonnarde R, Richard F, Albrieux C, Mahieu M, Arrighi M, Si-Larbi G, Jouneau PH, Gros V, Louwagie M, Roy S, Gong Y, Pan Y, Hu H, Bastien O, Jouhet J, Amato A, Maréchal E, Salvaing J.   +20 more
europepmc   +2 more sources

Protein delivery to living cells by thermal stimulation for biophysical investigation

Scientific Reports, 2022
Studying biomolecules in their native environment represents the ideal sample condition for structural biology investigations. Here we present a novel protocol which allows to delivery proteins into eukaryotic cells through a mild thermal stimulation ...
Francesco Torricella, Letizia Barbieri, Virginia Bazzurro, Alberto Diaspro, Lucia Banci   +4 more
doaj   +1 more source

Projekt for manufacturing of gears for Company Stab spol. s r. o. [PDF]

, 2020
Diplomová práca opisuje projekt na založenie novej divízie pre firmu ktorá sa zaoberá generálnymi opravami strojov. V prvej časti práce je rozoberaná teoretická časť o výrobnom procese ozubenia a ekonomická časť tejto práce. Hlávne časti práce sú analýza
Štefan Staník
core  

Conformational characterization of full-length X-chromosome-linked inhibitor of apoptosis protein (XIAP) through an integrated approach

IUCrJ, 2019
The X-chromosome-linked inhibitor of apoptosis protein (XIAP) is a multidomain protein whose main function is to block apoptosis by caspase inhibition. XIAP is also involved in other signalling pathways, including NF-κB activation and copper homeostasis.
Panagis Polykretis, Enrico Luchinat, Alessio Bonucci, Andrea Giachetti, Melissa A. Graewert, Dmitri I. Svergun, Lucia Banci   +6 more
doaj   +1 more source

NMR Spectroscopy Combined with Machine Learning Approaches for Age Prediction in Healthy and Parkinson’s Disease Cohorts through Metabolomic Fingerprints

Applied Sciences, 2022
Biological aging can be affected by several factors such as drug treatments and pathological conditions. Metabolomics can help in the estimation of biological age by analyzing the differences between predicted and actual chronological age in different ...
Giovanna Maria Dimitri, Gaia Meoni, Leonardo Tenori, Claudio Luchinat, Pietro Lió   +4 more
doaj   +1 more source

On the genus Bursaphelenchus Fuchs, 1937 (Nematoda: Parasitaphelenchinae) associated with wood and insects from declining forest trees in the Czech Republic [PDF]

, 2013
An overview of the genus Bursaphelenchus in the Czech Republic is presented, based on a recent survey for monitoring the presence of the pinewood nematode, Bursaphelenchus xylophilus, as well as on previous reports of this genus in the country.
Abelleira, Akbulut, Akbulut, Anonymous, Anonymous, Braasch, Braasch, Braasch, Braasch, Braasch, Braasch, Brzeski, Burgermeister, Běhalová, Evans, Evans, Ferris, Fonseca, Han, Korentchenko, Kubátová, Mota, Penas, Pfeffer, Polomski, Polomski, Postner, Robertson, Ryss, Seinhorst, Sláma, Sousa, Vrain, Whitehead, Čermák   +34 more
core   +1 more source

Survey dataset on pathologic internet use, problematic cell phone use and gambling through EUPI-A, CERM and SOGS-RA scales in high technological schools in the north of Spain

Data in Brief, 2019
The incursion of Information Technologies in the field of education is an undeniable fact that today includes immersion in media education in the classroom.
Francisco Javier Lena-Acebo, María Elena García-Ruiz   +1 more
doaj   +1 more source

Use of Recombinant Escherichia coli Strains in Immunofluorescence Assays for Melioidosis Diagnosis

Pathogens, 2021
Burkholderia pseudomallei is a Gram-negative bacterium and the causative agent of melioidosis in humans and animals in the tropics. The clinical manifestations of melioidosis are diverse, ranging from localized infections to whole-body sepsis.
Kanoknart Lantong, Jirarat Songsri, Sueptrakool Wisessombat, Wanida Mala, Warinda Prommachote, Wilaiwan Senghoi, Manas Kotepui, Jedsada Kaewrakmuk, Treenate Jiranantasak, Apichai Tuanyok, Wiyada Kwanhian Klangbud   +10 more
doaj   +1 more source