Results 141 to 150 of about 384,863 (297)

Current evidence and insights on single vs. double dose of basiliximab in adult solid organ transplant recipients: A systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this systematic review was to assess all available clinical data regarding the use of a single dose of basiliximab in solid organ transplantation compared to the standard double dosage, with particular interest in efficacy, safety and cost‐savings.
Alessio Provenzani, Braidon A. Lape, Anneliese M. Harp, Victoria Weisbrod, Lavinia Piazza   +4 more
wiley   +1 more source

The End Of Certainty [PDF]

SSRN Electronic Journal, 2021
openaire   +1 more source

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk, Ryan Jin, Fabio Tuzzolino, Giusy Ranucci, Donatella Madonia, Alessio Provenzani   +5 more
wiley   +1 more source

Pain Management During Neonatal Blood Sampling: An Overview of Systematic Reviews. [PDF]

Paediatr Neonatal Pain
Lord LG, Harding JE, Crowther CA, Lin L.
europepmc   +1 more source

Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul, H. Rob Taal, Jan Mazela, Ryszard Lauterbach, Irwin K. M. Reiss, Karel Allegaert, Robert B. Flint, Sinno H. P. Simons   +7 more
wiley   +1 more source

Strategies to improve recruitment to randomised trials. [PDF]

Cochrane Database Syst Rev
Parker A, Mongelli G, Piccolo-Lawrance C, Coleman E, Gkekas A, Wang HI, Dawson S, Green H, Way R, Rai A, Bruhn H, Sullivan F, Boxall C, Chan M, Manson P, Hewitt C, Fairhurst C, Clarke M, Treweek S.   +18 more
europepmc   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Testing construct validity of verbal versus numerical measures of preference uncertainty in contingent valuation [PDF]

The numerical certainty scale (NCS) and polychotomous choice (PC) methods are two widely used techniques for measuring preference uncertainty in contingent valuation (CV) studies.
Bennett, Jeffrey W., Akter, Sonia
core  

Effectiveness of Nurse-Led Case Management in Community Settings Among Older Adults: A Systematic Review and Meta-Analysis. [PDF]

Int J Older People Nurs
Mieda K, Kameyama M, Ota E, Yamada M.
europepmc   +1 more source

Clinical practice guideline for psoriasis management in Latin America. [PDF]

An Bras Dermatol
Valenzuela F, Castro Ayarza JR, Kaplan D, Londoño-García AM, Macías García KDR, Magariños G, Rivas Záldivar ES, Franco M, Cano S, Cortés C, Cárdenas PJ, Castro C, Ferreira R, Martínez S, Ibatá Bernal L, Castillo JC, Ospina J.   +16 more
europepmc   +1 more source