Results 31 to 40 of about 144,919 (268)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

CONSIDERATIONS REGARDING THE DIVORCE BY AGREEMENT OF THE SPOUSES, ACCORDING TO THE NOTARY PROCEDURE [PDF]

Challenges of the Knowledge Society, 2011
By amending the Family Code according to the provisions of the Law no. 202/2010 regarding some measures in order to speed the solving of processes (“Law of small reform”), representing the introduction to the New Civil Code adopted by the Law no.
ANCA-ANDREEA NISTOREANU
doaj  

Multidimensional Security Provision for Secure Communication in Vehicular Ad Hoc Networks Using Hierarchical Structure and End-to-End Authentication

IEEE Access, 2018
Vehicular ad hoc networks (VANETs) have been considered as one of the most influential applications of mobile ad hoc networks. The VANETs have also become an important part of Internet of Things.
Gulshan Kumar, Rahul Saha, Mritunjay Kumar Rai, Tai-Hoon Kim   +3 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Causes of visual impairment among patients applying for the visual disability certificate in Upper Egypt: a retrospective study

Journal of the Egyptian Ophthalmological Society
Aim To explore the causes of visual impairment in patients applying for the visual disability certificate in Upper Egypt. Patients and methods This was a retrospective observational study that included patients referred to “The Ministry of Social ...
Asmaa Hassan, Mahmoud Abdel-Radi, Heba M. Mohammed, Shymaa K. Hady   +3 more
doaj   +1 more source

Hábitos de estudio y aprendizaje autorregulado en estudiantes universitarios

Revista Educa UMCH, 2021
La presente investigación tuvo como objetivo general determinar si existe relación entre las variables hábitos de estudio y aprendizaje autorregulado. El diseño de estudio fue no experimental transversal de alcance correlacional.
Sandra Gabriela Terry Advíncula, Smits Dante Tucto Aguirre   +1 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Osmanlı’dan Erken Cumhuriyet Dönemine Miras Kalan Bir İlköğretim Meselesi; Muallim Muavinleri

Turkish History Education Journal, 2020
19. yüzyılda dağılma sürecine giren Osmanlı Devleti kötü gidişi engellemek adına ıslahatlar yapmaya başlamıştır. Bu bağlamda yapılan ıslahatlar arasında eğitim alanında yapılanlar oldukça dikkat çekicidir.
Ayse Yanardağ
doaj   +1 more source