Results 101 to 110 of about 1,045,115 (361)
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Stakeholders’ views on improving the organic certification system: Results from an EU level workshop [PDF]
The FP7 CERTCOST project has the overall objective to give recommendations to the public authorities and private actors in the whole organic certification chain on how to improve the organic food certification systems in terms of efficiency, transparency
Abay, Canan +3 more
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Labor Certification for Permanent Immigrant Admissions [PDF]
[Summary] The foreign labor certification program in the U.S. Department of Labor (DOL) is responsible for ensuring that foreign workers do not displace or adversely affect working conditions of U.S. workers.
Wasem, Ruth Ellen
core +1 more source
Robustness Certificates Against Adversarial Examples for ReLU Networks [PDF]
Sahil Singla, Soheil Feizi
openalex +1 more source
14 pages, 5 figures. To appear in 27th ACM International Conference on Hybrid Systems: Computation and Control Hong-Kong, 13-16 May ...
Vishnu Murali +2 more
openaire +2 more sources
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Overview of FAA's aircraft icing program [PDF]
An overview of the FAA's icing program is presented. The program involves certification of various types of aircraft for flight in known icing conditions, the study of icing conditions, and the preparation of certification standards.
Czekalski, L.
core +1 more source
Re: Performance on the Maintenance of Certification for Family Physicians (MC-FP) Examination: Comparison of Initial Certifiers with Experienced Physicians [PDF]
Edward J. Volpintesta
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source

