Results 81 to 90 of about 359,951 (311)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Benefits of Human Resource Certification: A Critical Analysis and Multi-Level Framework for Research [PDF]

open access: yes
Despite the huge success of marketing certification to human resources (HR) professionals, does it benefit individuals, employers, and the field of HR?
Herman Aguinis, Mark L. Lengnick-Hall
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Evaluating the IAQ and energy performance of ventilation systems in multifamily buildings [PDF]

open access: yesE3S Web of Conferences
Buildings must provide Indoor Air Quality (IAQ) to the best of their ability while maintaining high energy efficiency. Mechanical ventilation systems are central to this concern.
Kiani Zohreh   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

DINI Institutional Repository Certification and Beyond [PDF]

open access: yes, 2006
The DINI certificate for document and publication repositories aims to network document and publication repositories by pushing the use of standards and promoting interoperability and cooperation between German higher education institutions that run ...
Dobratz, Susanne
core   +1 more source

Detection of Flavobacterium spp. in Fresh Fish Meat Using a LAMP Visualization Technique Based on Novel Molecular Targets

open access: yesShipin gongye ke-ji
This study was dedicated to developing a visualization technique based on loop-mediated isothermal amplification (LAMP) with novel molecular targets, aiming to simultaneously, rapidly, and sensitively detect Flavobacterium spp. in fresh fish meat.
Baoqing ZHOU   +7 more
doaj   +1 more source

The Role of Certification in the Brazilian Fruit Chain [PDF]

open access: yes
Concerns about food safety and standards in the developed countries, particularly in Europe and the United States have made certification inevitable for worldwide fruit producers who target such export markets.
Andrea Cristina DORR
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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