Results 81 to 90 of about 1,045,115 (361)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Roadmap For Ethical Product Certification and Standard Setting Initiatives [PDF]

, 2009
The International Labor Rights Forum has developed a set of certification standards with the goal of addressing the root causes of factory and farm sweatshop conditions in global supply chains.
International Labor Rights Forum
core   +1 more source

UK consumer reactions to organic certification logos [PDF]

, 2013
Purpose - This paper considers the question of whether UK consumers recognise and trust organic certification logos and whether the presence of these logos on a product increases consumer willingness to pay for that product.
Gerrard, Catherine L, Hamm, Ulrich, Janssen, Meike, Padel, Susanne, Smith, Laurence   +4 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Detection of Flavobacterium spp. in Fresh Fish Meat Using a LAMP Visualization Technique Based on Novel Molecular Targets

Shipin gongye ke-ji
This study was dedicated to developing a visualization technique based on loop-mediated isothermal amplification (LAMP) with novel molecular targets, aiming to simultaneously, rapidly, and sensitively detect Flavobacterium spp. in fresh fish meat.
Baoqing ZHOU, Xudong MAO, Xiang NIE, Yingfei ZHU, Hongwei FAN, Wenqi XIONG, Xin WU, Bingfeng MA   +7 more
doaj   +1 more source

Safety Barrier Certificates for Stochastic Hybrid Systems [PDF]

, 2022
Abolfazl Lavaei, Sadegh Soudjani, Emilio Frazzoli   +2 more
openalex   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Alternative Certification: A Research Brief [PDF]

, 2011
Alternative teacher certification (ATC) encompasses a broad range of programs that prepare teachers in non-traditional, accelerated ways (Suell and Piotrowski 2007).
Hirshberg, Diane
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source