Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman +17 more
wiley +1 more source
Multi User Decision Support System For Teachers Sertification With HTTPS [PDF]
, 2012 Education quality is a key condition to realize the life of a developed nation, modern dan Prosperous. (Fasli Jalal 2008) Teacher quality greatly affect the effectiveness of learning (Suherman, 2007, Rink, 2002).
Edi, Setiawan
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Physician assistant/associate career flexibility: factors associated with specialty transitions
BMC Health Services ResearchBackground Physician assistants/associates (PAs), due to their broad medical education and certification, have the flexibility to change specialties throughout their careers. Prior studies suggest that between half and three-quarters exercise this option
Andrzej Kozikowski +9 more
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Establishing Local Certification Bodies In Developing and Transition Economies [PDF]
, 2006 There are certification bodies from Western countries offering their services all over the world providing efficient, reliable and qualified services.
Huber, Beate
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Pige Kexue Yu GongchengObjectiveLeather fiber-based materials are rich in collagen protein, which have unique morphological and structural characteristics, so they are highly sought after in the market.
Qiao LI +6 more
doaj +1 more source
Effect of the size of the seeds of the main and second cob of maize hybrid Maxima on physiologic quality of seeds being dried by dryer and air-dried [PDF]
علوم و فناوری بذر ایران, 2020 This study was aimed to determine the effect of seed size of the first (main) ear and the second ear and drying methods on seed quality of maize hybrid Maxima.
Zahra Radmanesh, Samad Mobasser
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Small-scale farmers' assessment of constraints and benefits from getting involved in various organic certification schemes for the domestic market in Thailand [PDF]
, 2019 The organic certification schemes, which propose links between small-scale farmers and domestic markets in developing and emerging countries, are increasingly diverse.
Faysse, Nicolas, Phiboon, Kassirin
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