Results 51 to 60 of about 940,374 (292)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Do the Second Circuit’s Legal Standards on Class Certification Incentivize Forum Shopping?: A Comparative Analysis of the Second Circuit’s Class Certification Jurisprudence [PDF]

open access: yes, 2016
The Class Action Fairness Act altered the jurisdictional landscape of class actions by relaxing the barriers to satisfying diversity jurisdiction in federal court.
Sharma, Shrey
core   +1 more source

Certifying Services in Cloud: The Case for a Hybrid, Incremental and Multi-layer Approach [PDF]

open access: yes, 2012
The use of clouds raises significant security concerns for the services they provide. Addressing these concerns requires novel models of cloud service certification based on multiple forms of evidence including testing and monitoring data, and trusted ...
Damiani, E., Maña, A., Spanoudakis, G.
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Evaluation of Indigenous Entomopathogenic Nematodes as Potential Biocontrol Agents against Popillia japonica (Coleoptera: Scarabaeidae) in Northern Italy

open access: yesInsects, 2020
The natural presence of entomopathogenic nematodes (EPNs) has been investigated in the Piedmont region (Northern Italy) in areas infested by the Japanese beetle Popillia japonica. Thirty-nine out of 155 soil samples (25.2%) were positive for EPNs.
Giulia Torrini   +11 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Airworthiness Certification of Civil Aviation Materials

open access: yesCailiao gongcheng, 2017
Based on years of airworthiness regulations research, combined with the experience of airworthiness certification of civil aviation products, the airworthiness requirement to materials for civil aviation products was analyzed.
SHEN Xiao-ming   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Certification of public organic procurement in Denmark, Finland, Italy and Norway as compared to Germany [PDF]

open access: yes, 2010
In the iPOPY project (innovative Public Organic food Procurement for Youth), one of the tasks was to map the challenges linked to the supply chains of organic food, and to which extent the participating countries have developed any form of certification ...
Lukas, Melanie   +2 more
core  

Synthesis and Lithium Storage Properties of Li-Mn-O compounds: Crystal Growth of LiMn2O4 and Li2MnO3

open access: yesInternational Journal of Electrochemical Science, 2014
The present work describes using Y-MnOOH nanorods as a self-template to form Li-Mn-O compounds via hydrothermal process and state reaction, and a key finding in phase transition from cubic to monoclinic with Li content increasing. As the cathode material
Bingjing Li   +3 more
doaj   +1 more source

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