Results 51 to 60 of about 466,653 (340)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Airworthiness Certification of Civil Aviation Materials

open access: yesCailiao gongcheng, 2017
Based on years of airworthiness regulations research, combined with the experience of airworthiness certification of civil aviation products, the airworthiness requirement to materials for civil aviation products was analyzed.
SHEN Xiao-ming   +2 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Online simultaneous determination of lactoferrin and immunoglobulin G in dairy products by two-dimensional liquid chromatography

open access: yesShipin yu jixie
ObjectiveA method of two-dimensional liquid chromatograohy was established to simultaneously determine the content of lactoferrin and immunoglobulin G in dairy products.MethodsThe pretreated samples were directly injected into the constructed system ...
CHEN Qin   +4 more
doaj   +1 more source

Evaluating the IAQ and energy performance of ventilation systems in multifamily buildings [PDF]

open access: yesE3S Web of Conferences
Buildings must provide Indoor Air Quality (IAQ) to the best of their ability while maintaining high energy efficiency. Mechanical ventilation systems are central to this concern.
Kiani Zohreh   +4 more
doaj   +1 more source

Death Certification: Errors and Interventions

open access: yesClinical Medicine Research, 2019
Objective Death certificates are legal documents containing critical information. Despite the importance of accurate certification, errors remain common.
L. Schuppener, K. Olson, Erin G. Brooks
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Is voluntary certification of tropical agricultural commodities achieving sustainability goals for small-scale producers? A review of the evidence

open access: yes, 2017
Over the last several decades, voluntary certification programs have become a key approach to promote sustainable supply chains for agricultural commodities.
R. DeFries   +4 more
semanticscholar   +1 more source

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