Results 41 to 50 of about 16,741 (266)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Management of Pulse Beetle in Green Gram Seed Using Modified Atmosphere

International Journal of Bio-Resource and Stress Management, 2022
The experiment was conducted at Seed Research and Technology Center, PJTSAU, Rajendranagar, Hyderabad, Telangana State, India during June, 2019 under laboratory conditions using modified atmosphere with elevated levels of CO2  in two varieties of green ...
K. Kanaka Durga, T. Sowmya, Kamala Venkateshwaran, K. Keshavulu, Vidyasagar   +4 more
doaj  

Review of Professionals Accreditation Systems and their relation to Higher Education Studies in the branch of Engineering

Multidisciplinary Journal for Education, Social and Technological Sciences, 2014
This paper aims to analyze and compare the accreditation systems of people applying to higher education professionals independently of the area of accreditation to which they belong.
Juan R. Lama Ruiz, Alejandro M. Martín Gómez, Mª Jesús Ávila Gutiérrez, Francisco Aguayo González   +3 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Practical Implementation of Various Public Key Infrastructure Models

Безопасность информационных технологий, 2016
The paper proposes a short comparative analysis of the contemporary models of public key infrastructure (PKI) and the issues of the PKI models real implementation. The Russian model of PKI is presented.
Dmitriy Anatolievich Melnikov, Vitaliy Grigorievich Ivanenko, Tatiana Alexandrovna Kondratyeva, Anton Dmitrievich Melnikov   +3 more
doaj  

Halal Certification for Non-Muslim-Owned Restaurants in Brunei Darussalam

Parewa Saraq
Halal certification is a central institutional mechanism for strengthening Muslim consumer confidence in restaurants and food premises within Brunei Darussalam.
Hafini bin Mahmud, Cecep Soleh Kurniawan
doaj   +1 more source

Air Operators’ Safety Assurance System

ITM Web of Conferences, 2017
Construction of air operators’ safety assurance system is important for national civil aviation authority to perform the safety oversight work systematically and efficiently on the air operators.
Xie Zhi-Hui
doaj   +1 more source

Environmental Authority: Transformations and Relocations in Global Modernity

Desenvolvimento e Meio Ambiente, 2008
As a public good, the environment has traditionally been handled by public authorities. However, withglobalization conventional state environmental authority is transformed, relocated and deterritorialized.New non-state environmental authorities emerge ...
Arthur P.J. Mol
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source