Results 71 to 80 of about 16,741 (266)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Role of Indonesian Council of Ulama in Halāl Certification and Product Guarantee

Journal of Islamic Thought and Civilization, 2023
The current research analysed the role of Indonesian Council of Ulama in halāl certification after the enactment of Law No. 33 of 2014. The Indonesian Council of Ulama is Indonesia’s peak clerical body with the authority to specify halāl and Harām fatwas
Abdul Rachman Abdul, Ashar Johnsan Khokhar   +1 more
doaj  

SERTIFIKASI HALAL DI INDONESIA (Analisis Kuasa Simbolik dalam Kontestasi Fatwa Majelis Ulama Indonesia)

El Barka, 2018
: The MUI's symbolic power over halal certification in Indonesia constructed by the habitus of Muslim consumers who are becoming aware of halal lifestyles. beside it, the symbolic capital of the MUI and the political and social religious fields.
Suad Fikriawan
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

SELF DECLARE DALAM PROSES PENETAPAN SERTIFIKASI HALAL

Al-Adl
This study aims to examine and analyze the regulatory framework of the self-declaration mechanism in the halal certification process and the adequacy of the normative basis for oversight by the Halal Product Assurance Organizing Agency (BPJPH) under Law ...
Nahdhah Nahdhah, Iwan Riswandie
doaj   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Construction of continuous certification index system for ICU professional nurses based on SMART principle

Huli yanjiu, 2017
Objective: To construct a continuous certification index system for ICU specialist nurses based on SMART principles.Methods:On the basis of literature review，follow the principle of SMART，Using Delphi method and analytic hierarchy process to carry out ...
秦君玫, 张庆庆, 王笑笑
doaj  

Misconception about Halal Certification Placement on Non-Food Commodities: State Coercion over the Territory of Ijtihad

Al-Manahij: Jurnal Kajian Hukum Islam
The obligation of halal certification for commodity products has created many dilemmas, one of which is the placement of the halal label on non-consumer goods.
Abdul Hamid, Agus Fakhrina, Fathul Aminudin Aziz, Mansur Chadi Mursid   +3 more
doaj   +1 more source

IGR Token-Raw Material and Ingredient Certification of Recipe Based Foods Using Smart Contracts

Informatics, 2019
The use of smart contracts and blockchain tokens to implement a consumer trustworthy ingredient certification scheme for commingled foods, i.e., recipe based, food products is described.
Ricardo Borges dos Santos, Nunzio Marco Torrisi, Erick Reyann Kasai Yamada, Rodrigo Palucci Pantoni   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source