PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian +13 more
wiley +1 more source
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
wiley +1 more source
A novel approach to the production of Δ<sup>9</sup>-THC and CBN certified reference materials. [PDF]
de Carvalho LJ +7 more
europepmc +1 more source
Survey Result of the Counting Efficiency of Gamma Counter by Certified Reference Materials. [PDF]
Bang JI +4 more
europepmc +1 more source
A BCP‐derived buried‐interface strategy establishes Na‐BCS as a chemically bonded molecular bridge. By combining sulfonate anchoring to SnO2 with preserved BCP–Pb2+ coordination, Na‐BCS simultaneously passivates oxide‐ and perovskite‐side defects, suppresses non‐radiative recombination, and delivers a surface recombination velocity of 8.6 cm s−1, a ...
Dong Hyun Kim +9 more
wiley +1 more source
The application of digital PCR to characterize genomic DNA certified reference materials of genetically modified papaya YK1601. [PDF]
He G +7 more
europepmc +1 more source
Between-bottle homogeneity test of new certified reference materials employing wavelength dispersive X-ray fluorescence spectrometry. [PDF]
Idris AM.
europepmc +1 more source
This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim +8 more
wiley +1 more source
Certified reference materials for GMO analysis-more than 25 years of GMO CRM production at EC JRC. [PDF]
Trapmann S, Linsinger TPJ, Koeber R.
europepmc +1 more source
On the use of certified reference materials for assuring the quality of results for the determination of mercury in environmental samples. [PDF]
Bulska E +3 more
europepmc +1 more source

