Results 51 to 60 of about 372,353 (307)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Certified reference materials for neutron dosimetry [PDF]
, 2016 Factsheet summarising the CRMs from JRC-IRMM for neutron dosimetryJRC.D-Institute for Reference Materials and Measurements ...
LINSINGER Thomas
core
Certification of Plasmid DNA containing 98140 Maize DNA Fragments - Certified Reference Material ERM®-AD427 [PDF]
, 2011 This report describes the preparation, characterisation, stability and suitability of the certified reference material (CRM) ERM-AD427, which contains a plasmid (pIRMM-0090) carrying a defined 2'-desoxyribonucleic acid (DNA) fragment specific for a ...
BROEDERS Sylvia +7 more
core +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Certified reference materials for veterinary drugs [PDF]
, 2016 This leaflet summarises the CRMs for veterinary drugsJRC.D-Institute for Reference Materials and Measurements ...
LINSINGER Thomas
core
Certification of a Maize NK603 Reference Material for its DNA Copy Number Ratio - Certified Reference Material ERM®-BF415e [PDF]
, 2011 This report describes the certification of the Certified Reference Material (CRM) ERM-BF415e for its DNA copy number ratio. This CRM is composed of genetically modified NK603 maize seed and conventional maize seed powders. The ERM-BF415e is part of a set
CORBISIER Philippe +6 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung +7 more
wiley +1 more source
Certified reference materials for testing of mycotoxins [PDF]
, 2016 This factsheet summarises the CRMs from JRC-IRMM for testing of mycotoxinsJRC.D-Institute for Reference Materials and Measurements ...
LINSINGER Thomas, STROKA Joerg
core
CERTIFICATION REPORT The certification of the absorbed energy (150 J nominal) of Charpy V-notch reference test pieces for tests at 20 °C: ERM®-FA415af [PDF]
, 2016 This certification report describes the processing and characterisation of ERM®-FA415af, a batch of Charpy V-notch certified reference test pieces certified for the absorbed energy (KV).
DEAN Alan +2 more
core +1 more source
Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein +13 more
wiley +1 more source