Results 101 to 110 of about 35,641 (262)

Cuproptosis Facilitates Chronic Skin Inflammation by Regulating the α‐Ketoglutarate/H3K4me3/Ferritin Heavy Chain 1 Signaling Pathway‐Mediated Ferroptosis

MedComm, Volume 6, Issue 10, October 2025.
Cuproptosis plays critical roles in psoriasis and atopic dermatitis (AD). SLC31A1‐mediated cuproptosis increases α‐ketoglutarate, activating KDM5B, which demethylates H3K4me3 domains in FTH1, lowering its transcription and promoting ferroptosis, thus advancing inflammatory skin diseases.
Pian Yu, Kaixuan Li, Shifu Luo, Rongxuan Yan, Xiaoqing Yi, Chi Fang, Sihui Ma, Guanming Wang, Fanyan Luo, Xiang Chen, Cong Peng, Jie Li   +11 more
wiley   +1 more source

Micronutrient deficiencies after pancreatico‐duodenectomy: A narrative review of the literature and recommendations for clinical practice

Nutrition in Clinical Practice, Volume 40, Issue 5, Page 1073-1092, October 2025.
Abstract Micronutrient uptake is impaired after pancreatico‐duodenectomy (PD) because of malabsorption, reduced absorptive capacity, and poor oral intake. Biochemical depletion is reported in cohort studies, but deficiency states are predominantly reported in case reports, making it difficult to assess occurrence rates.
Mary E. Phillips, Callum Livingstone, Adam E. Frampton, Kathryn H. Hart   +3 more
wiley   +1 more source

Indices of peroxidation of lipids of biological membranes and endogenous intoxication in patients with psoriasis on the background of chronic viral hepatitis С

Vestnik Dermatologii i Venerologii, 2019
Aim. To study the features of lipid peroxidation of biological membranes and accumulation of toxic metabolites in the body of patients with psoriasis, depending on the presence of concomitant chronic viral hepatitis C.Materials and methods. In the survey,
M. Yu. Marzhokhova, Ashour Ahmad Mahmud Hussein, A. R. Marzhokhova   +2 more
doaj   +1 more source

Wilson's disease: A patient undiagnosed for 18 years [PDF]

, 2006
Wilson's disease, an autosomal recessive disorder of copper metabolism, is the most common inherited hepatic disease in Hong Kong. Diagnosis is based on the presence of Kayser-Fleischer rings, typical neurological symptoms, and/or a low serum ...
Fan, ST, Lam, CW, Liu, CL, Mak, CM, Tam, S   +4 more
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Diagnosis and Monitoring Pathways Using Non‐Invasive Tests in Patients With Alpha‐1 Antitrypsin Deficiency‐Associated Liver Disease: Results From an Expert Delphi Panel

United European Gastroenterology Journal, Volume 13, Issue 8, Page 1446-1455, October 2025.
ABSTRACT Background and Aims The severe alpha‐1 antitrypsin deficiency (AATD) genotype Pi*ZZ increases the risk of liver disease (AATD‐LD) and lung disease. While non‐invasive tests (NITs) are widely used for fibrosis stage and monitoring of all liver diseases, the consensus for use in AATD‐LD is limited.
Virginia C. Clark, Mark A. Price, Jon Russo, Rohit Loomba, Alice M. Turner, Pavel Strnad   +5 more
wiley   +1 more source

Dysregulation of Different Modes of Programmed Cell Death in Rheumatoid Arthritis Fibroblast‐Like Synoviocyte

International Journal of Rheumatic Diseases, Volume 28, Issue 10, October 2025.
ABSTRACT Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by chronic synovitis and skeletal joint deformities, often accompanied by systemic symptoms. Over the past few decades, various susceptibility factors for RA have been revealed, and numerous therapeutic drugs have been developed, including analgesics, glucocorticoids ...
Xiaorong Zhi, Hong Zhu, Xiaoyan Sun, Zhaoxia Wang, Lin Wang, Guanhua Song   +5 more
wiley   +1 more source

Copper Homeostasis, Emerging Central Players in Cancer Immunotherapy

Journal of Cellular and Molecular Medicine, Volume 29, Issue 19, October 2025.
ABSTRACT Copper ions serve as multifunctional signalling molecules that are integral to various cellular processes in vivo, including cell proliferation, apoptosis and migration. The storage, transport and homeostatic regulation of intracellular copper are closely linked to mitochondrial function.
Chengxin Chen, Mengle Peng, Shuhong Liang, Chunwei Li, Lili Zhu, Yaqi Yang, Lifeng Li, Wenhua Xue   +7 more
wiley   +1 more source

Wilson’s disease in a child: a difficult path to diagnosis (clinical case)

Zdorovʹe Rebenka
The article presents data on the etiology, pathogenesis and clinical manifestations of Wilson’s disease, and also describes a diagnostically complex clinical case and own observation of a patient with Wilson’s disease. Wilson’s disease is a chronic liver
O.M. Вabadzhanian, O.V. Shutova, N.V. Pavlenko, I.G. Solodovnychenko, K.V. Voloshyn   +4 more
doaj   +1 more source

Turnover of the Copper and Protein Moieties of Ceruloplasmin [PDF]

, 1960
David Gitlin, Charles A. Janeway
openalex   +1 more source

Keragaman Protein Plasma Darah pada Kambing Kejobong dan Kambing Peranakan Ettawa [PDF]

, 2013
The objective of this study was to evaluate the genotype variations of Kejobong and Ettawa Grade (EG) goats based on the blood plasm protein using gel polyacrilamide electrophoresis (PAGE).
Dewanti, D. R. (Dyah), Kurnianto, E. (Edi), Sutopo, S. (Sutopo)   +2 more
core