Results 131 to 140 of about 17,515 (182)

Heterogeneity of Human Ceruloplasmin

Science, 1960
Subfractionation of purified human ceruloplasmin, prepared from plasma of 9109 donors, has been carried out by chromatography on columns of diethylaminoethyl cellulose and hydroxylapatite. Electrophoretic analyses of these subfractions on starch gels, at p H 8.5 and 5.7, reveal the presence of at least four ...
A G, MORELL, I H, SCHEINBERG
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Ceruloplasmin and cardiovascular disease

Free Radical Biology and Medicine, 2000
Transition metal ion-mediated oxidation is a commonly used model system for studies of the chemical, structural, and functional modifications of low-density lipoprotein (LDL). The physiological relevance of studies using free metal ions is unclear and has led to an exploration of free metal ion-independent mechanisms of oxidation.
P L, Fox, B, Mazumder, E, Ehrenwald, C K, Mukhopadhyay   +3 more
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Molecular pathology of ceruloplasmin

Biochemical Genetics, 1972
Individual preparations of CP isolated from one normal donor and two homozygotes for the “Wilson's disease gene” were subjected to a comparative structural and analytical examination. Analysis of CP tryptic hydrolysate by the peptide map technique revealed 64–66 peptides in each sample.
S A, Neifakh, I M, Vasiletz, M M, Shavlovsky   +2 more
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Mitochondrial ceruloplasmin of mammals

Molecular Biology, 2005
Using immunoblotting method it was found out that ceruloplasmin (Cp) polypeptides are revealed in mitochondria of rats, isolated from brain, liver, testicles and mammary gland. Cp is localized in matrix and inner membranes of mitochondria. Its molecular weight corresponds to the non-glycosilated form of the protein. Computer analysis did not reveal any
A V, Vasin, N A, Platonova, R G, Povalikhin, S A, Klotchenko, S A, Samsonov, N V, Tsymbalenko, L V, Puchkova   +6 more
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Interaction of Lactoferrin with Ceruloplasmin

Archives of Biochemistry and Biophysics, 2000
When added to human blood serum, the iron-binding protein lactoferrin (LF) purified from breast milk interacts with ceruloplasmin (CP), a copper-containing oxidase. Selective binding of LF to CP is evidenced by the results of polyacrylamide gel electrophoresis, immunodiffusion, gel filtration, and affinity chromatography.
E T, Zakharova, M M, Shavlovski, M G, Bass, A A, Gridasova, M O, Pulina, V, De Filippis, M, Beltramini, P, Di Muro, B, Salvato, A, Fontana, V B, Vasilyev, V S, Gaitskhoki   +11 more
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On the conformation of porcine ceruloplasmin

Archives of Biochemistry and Biophysics, 1969
Abstract The ultracentrifugal behavior and optical properties of porcine ceruloplasmin have been measured to elucidate the conformation of the protein molecule. The molecular weights of apo- and reduced porcine ceruloplasmin are almost identical with that of native protein, i.e., about 150,000, whereas their sedimentation velocities are slightly ...
Y, Hibino, T, Samejima, S, Kajiyama, Y, Nosoh   +3 more
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Production of Melanins by Ceruloplasmin

Pigment Cell Research, 1998
It was shown that ceruloplasmin, apart from the known oxidative conversion of dopamine into melanin, can also produce (DHI)‐melanin from 5,6‐dihydroxyindole and THP‐melanin from tetrahydropapaveroline. Ceruloplasmin acts as an oxidase and the kinetic parameters for these oxidative reactions are reported.
ROSEI, Maria Anna, Cesira Foppoli, Xin Tao Wang, COCCIA, Raffaella, Mircea Alexandru Mateescu   +4 more
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Ceruloplasmin in human semen

Experientia, 1966
La ceruloplasmine a ete determinee dans le liquide spermatique de l'homme. On a trouve des valeurs basses pour cette enzyme et une diminution significative au point de vue statistique a ete observee dans les cas d'azoospermie.
L A, de Abreu, R R, Abreu, H, Povoa
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Ceruloplasmin receptors of erythrocytes

Biochemical and Biophysical Research Communications, 1984
Mammalian erythrocytes have been shown to bind 125I labeled ceruloplasmin. Binding was reversible and specific. Scatchard analysis yielded linear plots with a Kd of approximately 5nM. The binding site appeared to be a protein located on the cell surface.
G, Barnes, E, Frieden
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Ceruloplasmin in neurodegenerative diseases

Biochemical Society Transactions, 2008
Two decades ago, patients lacking circulating serum ceruloplasmin (Cp) presented with neurodegeneration associated with brain iron accumulation. These patients, with mutations in the MCO (multi-copper oxidase), Cp, revealed an essential role for Cp in iron homoeostasis.
Sarah J, Texel, Xueying, Xu, Z Leah, Harris   +2 more
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