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Nature, 1959
CERULOPLASMIN is one of the minor components of plasma proteins. Most of the numerous publications which have appeared in the past several years are concerned with the evaluation and clinical significance of hypo- and hyper-ceruloplasminaemia. Nevertheless, the biological role of ceruloplasmin is still unknown.
M. Quentin, M. Steinbuch
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CERULOPLASMIN is one of the minor components of plasma proteins. Most of the numerous publications which have appeared in the past several years are concerned with the evaluation and clinical significance of hypo- and hyper-ceruloplasminaemia. Nevertheless, the biological role of ceruloplasmin is still unknown.
M. Quentin, M. Steinbuch
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Heterogeneity of Human Ceruloplasmin [PDF]
Science, 1960 Subfractionation of purified human ceruloplasmin, prepared from plasma of 9109 donors, has been carried out by chromatography on columns of diethylaminoethyl cellulose and hydroxylapatite. Electrophoretic analyses of these subfractions on starch gels, at p H 8.5 and 5.7, reveal the presence of at least four ...
I. Herbert Scheinberg, Anatol G. Morell
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Heterogeneity of ceruloplasmin
Clinica Chimica Acta, 1962Abstract 1. (1) The heterogeneity of serum ceruloplasmin was studied by starch gel electro-phoresis, immuno-electrophoresis and ultracentrifugal techniques. 2. (2) All the preparations of ceruloplasmin, prepared by larger scale methods, were found to consist of multiple components with the characteristics of ceruloplasmin.
M.D. Poulik, A.G. Bearn
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Ceruloplasmin and cardiovascular disease
Free Radical Biology and Medicine, 2000Transition metal ion-mediated oxidation is a commonly used model system for studies of the chemical, structural, and functional modifications of low-density lipoprotein (LDL). The physiological relevance of studies using free metal ions is unclear and has led to an exploration of free metal ion-independent mechanisms of oxidation.
Chinmay K. Mukhopadhyay +3 more
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Ceruloplasmin in neurodegenerative diseases
Brain Research Reviews, 2005For decades, abnormalities in ceruloplasmin (Cp) synthesis have been associated with neurodegenerative disease. From the early observation that low circulating serum ceruloplasmin levels served as a marker for Wilson's disease to the recent characterization of a neurodegenerative disorder associated with a complete lack of serum ceruloplasmin, the link
Vadim Vassiliev +2 more
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Dolphin ceruloplasmin: The first proteolytically stable mammalian ceruloplasmin
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 19921. Ceruloplasmin, the blue protein of the plasma of vertebrates, was isolated from dolphin, a marine mammal. The protein showed overall physico-chemical parameters very similar to those of all other mammalian ceruloplasmins. The spectroscopic properties indicated a conservation of the copper binding sites. 2.
M. C. Bonaccorsi di Patti +4 more
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Production of Melanins by Ceruloplasmin
Pigment Cell Research, 1998It was shown that ceruloplasmin, apart from the known oxidative conversion of dopamine into melanin, can also produce (DHI)‐melanin from 5,6‐dihydroxyindole and THP‐melanin from tetrahydropapaveroline. Ceruloplasmin acts as an oxidase and the kinetic parameters for these oxidative reactions are reported.
ROSEI, Maria Anna +4 more
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