Results 11 to 20 of about 655,611 (249)

Identification and validation of the high expression of pseudogene TCAM1P in cervical cancer via integrated bioinformatics analysis

Cancer Cell International, 2022
Background HPV as the main cause of cervical cancer has long been revealed, but the detailed mechanism has not yet been elucidated. The role of testis/cancer antigen in cervical cancer has been revealed.
Yuanhang Zhu, Chenchen Ren, Li Yang, Zhenan Zhang, Meiyuan Gong, Kebing Chen   +5 more
doaj   +1 more source

Self-sampling and HPV DNA testing for cervical precancer screening in a cohort of nuns in Ghana: a cross-sectional cohort studyResearch in context

EClinicalMedicine, 2023
Summary: Background: The need for cervical cancer screening has been emphasised in at-risk cohorts of women to reduce their risk of cervical cancer. Some women with decreased risk of acquiring human papillomavirus (HPV) infections, such as Catholic nuns,
Kofi Effah, Ethel Tekpor, Joseph Emmanuel Amuah, Nana Owusu M. Essel, Seyram Kemawor, Esu Aku Catherine Morkli, Esther Lamptey–Mills, Comfort Mawusi Wormenor, Lawrencia Serwaa Manu, Gifty Belinda Klutsey, Stephen Danyo, Patrick Kafui Akakpo   +11 more
doaj   +1 more source

The effect of TLR4 on the growth and local inflammatory microenvironment of HPV-related cervical cancer in vivo

Infectious Agents and Cancer, 2020
Background Cervical cancer is the most common malignancy of the female lower genital tract. In our previous study, we found that TLR4 promotes cervical cancer cell growth in vitro.
Ninghong Jiang, Feng Xie, Limei Chen, Fang Chen, Long Sui   +4 more
doaj   +1 more source

Castle man disease: a case report and review of the literature

The Pan African Medical Journal, 2014
The Castleman disease (CD) is a rare disease of unknown etiology, characterized histologically by angiofollicular lymphoid hyperplasia. It comes in two forms, unicentric and multicentric.
Mounir Kettani, Nabil Touiheme, Hicham Attifi, Mounir Hmidi, Ali Boukhari, Mohamed Zalagh, Abdelhamid Messary   +6 more
doaj   +1 more source

Acute idiopathic velopharyngeal insufficiency

The Pan African Medical Journal, 2020
Idiopathic velopharyngeal insufficiency is a rare clinical entity.Typical clinical features are rhinolalia, and nasopharyngeal regurgitation. It is usually observed in children. We report a case of a 28-year-old female with this rare disorder.
Malika El Omri, Oumaima Gabsi, Wassim Kermani, Mohamed Abdelkefi   +3 more
doaj   +1 more source

Synchronous HPV genotyping and quantification assay to predict the outcome of high risk HPV infection: report of 2 784 cases

Di-san junyi daxue xuebao, 2020
Objective To explore the law of natural outcome of high-risk human papillomavirus (HR-HPV) infection and determine the optimal cutoff for prediction of the infection natural outcome based on the synchronous HPV genotyping and quantification.
LONG Xin, YANG Jun, ZHOU Deping
doaj   +1 more source

Clinical validation of the Roche cobas HPV test on the Roche cobas 5800 system for the purpose of cervical screening

Microbiology Spectrum
This study assessed the relative clinical sensitivity and specificity, as well as reproducibility, for high-risk HPV types of the Roche cobas HPV test when processed using the Roche cobas 5800 system.
Nikita Mehta, Marco Ho Ting Keung, Eunice Pineda, Elliott Lynn, Dagnachew Fetene, Alvin Lee, Nicolas Hougardy, Amelie Heinrichs, Hiu Tat Mark Chan, Marc Arbyn, Marion Saville, David Hawkes   +11 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Dysphagia revealing diffuse idiopathic skeletal hyperostosis: report of two cases and literature review

The Pan African Medical Journal, 2019
Diffuse Idiopathic Skeletal Hyperostosis (DISH) also known as Forestier's disease, is a musculo-squelettic disorder characterized by the calcification of ligaments essentially the vertebral longitudinal anterior ligament. Men are generally affected.
Monia Ghammam, Jihene Houas, Mouna Bellakhdher, Mohamed Abdelkefi   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source