Results 41 to 50 of about 966,128 (305)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

HPV types and cofactors causing cervical cancer in Peru. [PDF]

, 2001
We conducted a hospital-based case-control study in Peru of 198 women with histologically confirmed cervical cancer (173 squamous cell carcinomas and 25 cases of adenocarcinoma/adenosquamous carcinoma) and 196 control women.
Muñoz, N, J Walboomers, I Guerrero, E Caceres, Santos, C, Galdos, O, Castillo, M, Walboomers, J, S Klug, Caceres, E, C Velarde, M Almonte, Klug, S, O Galdos, Alvarez, M, N Muñoz, Meijer, C, C Santos, M Alvarez, Guerrero, I, C Meijer, Almonte, M, M Castillo, Velarde, C   +23 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Assessing high-risk human papillomavirus-based cervical precancer screening recommendations and implications among women aged 60/65 years and older in Ghana

Scientific Reports
We aimed to assess the prevalence of high-risk HPV (hr-HPV) infection, cervical lesions observed through visual inspection, and abnormal cytology among women aged ≥ 60 years screened by the Cervical Cancer Prevention and Training Centre, Ghana.
Kofi Effah, Ethel Tekpor, Yaw Ohene-Bredu, Sadat Ibrahim, Stephen Tetteh Engmann, Stephen Danyo, Seyram Kemawor, Annita Edinam Dugbazah, Famous Afudego, Yohane Teye Kitcher, Gifty Belinda Klutsey, Bernard Hayford Atuguba, Nana Owusu Mensah Essel   +12 more
doaj   +1 more source

CERVICAL EROSIONS

Annals of Surgery, 1920
n ...
openaire   +3 more sources

Posterior cervical foraminotomy for cervical radiculopathy: should cervical alignment be considered?

Journal of Spine Surgery, 2019
Concerning of progression of deformity, it is reluctant to utilize a posterior approach if preoperative sagittal alignment is kyphotic or straight. The purpose of this study was to determine interval changes in cervical segmental angles after posterior cervical foraminotomy (PCF) and analyzing factors affecting cervical sagittal re-alignment in the ...
Seok Won, Chung, Hyun Jun, Kim, Sang Ho, Lee, Shin Young, Lee, Min Soo, Kang, Yong Hwan, Shin, Chan Hong, Park   +6 more
openaire   +2 more sources

Report of the parliamentary review committee regarding the New Zealand cervical screening programme: 2015 [PDF]

, 2015
Highlights National Cervical Screening Programme (NCSP) successes and identifies key areas that will further strengthen the programme. Executive summary The National Cervical Screening Programme (NCSP) has been highly successful in reducing the ...
Ministry of Health (New Zealand)
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

A prospective study of vaginal topical pretreatment of compound sea-buckthorn oil suppository in postmenopausal women prior to colposcopy

Scientific Reports
Postmenopausal women are faced with difficulties in colposcopy, such as easy bleeding from epithelial atrophy, and thinning, atypical colposcopy images, unsatisfactory exposure, and decreased sensitivity of colposcopy. We aimed to improve the sensitivity
Yi Yu, Qing Li, Yuankui Cao, Hongwei Zhang, Yu Song, Qing Cong, Long Sui, Limei Chen   +7 more
doaj   +1 more source