Results 41 to 50 of about 415,648 (260)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Prevalence of type-specific HPV infection by age and grade of cervical cytology: data from the ARTISTIC trial. [PDF]

, 2008
Human papillomavirus (HPV) infection causes cervical cancer and premalignant dysplasia. Type-specific HPV prevalence data provide a basis for assessing the impact of HPV vaccination programmes on cervical cytology.
Bailey, A, C Thomson, Roberts, C, S Moss, Sargent, A, Peto, J, J Peto, Kitchener, HC, Moss, S, A Sargent, A Bailey, M Desai, M Almonte, Thomson, C, Mather, J, Desai, M, H C Kitchener, A Turner, C Roberts, Almonte, M, J Mather, ARTISTIC Study Group, Turner, A   +22 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

The Swedish Cervical Screening Cohort

Scientific Data
The Cervical Screening Cohort enrols women screened for human papillomavirus (HPV) and cervical abnormalities within the capital region of Sweden from the organised screening program and the non-organised testing of cervical samples.
Joakim Dillner, Laila Sara Arroyo Mühr, Sara Nordqvist Kleppe, Jiangrong Wang, Helena Andersson, Miriam Elfström, Roxana Merino, Karin Sundström   +7 more
doaj   +1 more source

Dysphagia revealing diffuse idiopathic skeletal hyperostosis: report of two cases and literature review

The Pan African Medical Journal, 2019
Diffuse Idiopathic Skeletal Hyperostosis (DISH) also known as Forestier's disease, is a musculo-squelettic disorder characterized by the calcification of ligaments essentially the vertebral longitudinal anterior ligament. Men are generally affected.
Monia Ghammam, Jihene Houas, Mouna Bellakhdher, Mohamed Abdelkefi   +3 more
doaj   +1 more source

Report of the parliamentary review committee regarding the New Zealand cervical screening programme: 2015 [PDF]

, 2015
Highlights National Cervical Screening Programme (NCSP) successes and identifies key areas that will further strengthen the programme. Executive summary The National Cervical Screening Programme (NCSP) has been highly successful in reducing the ...
Ministry of Health (New Zealand)
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SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

A huge retropharyngeal lipoma: a rare cause of dysphagia: a case report and literature review

The Pan African Medical Journal, 2019
Dysphagia is commonly seen after a cerebral vascular accident. It is rarely caused by lipomas of the retropharyngeal region which are rare benign mesenchymal neoplasms.
Monia Ghammam, Jihene Houas, Mouna Bellakhdher, Mohamed Abdelkefi   +3 more
doaj   +1 more source

Synchronous HPV genotyping and quantification assay to predict the outcome of high risk HPV infection: report of 2 784 cases

Di-san junyi daxue xuebao, 2020
Objective To explore the law of natural outcome of high-risk human papillomavirus (HR-HPV) infection and determine the optimal cutoff for prediction of the infection natural outcome based on the synchronous HPV genotyping and quantification.
LONG Xin, YANG Jun, ZHOU Deping
doaj   +1 more source

Cervical screening in Australia 2010-2011 [PDF]

, 2013
This paper presents the latest national statistics monitoring the National Cervical Screening Program, which aims to reduce incidence, morbidity and mortality from cervical cancer.Summary:The National Cervical Screening Program (NCSP) aims to reduce

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