Results 61 to 70 of about 1,341,656 (313)

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Expanding management strategies for cervical precancerous lesions in resource-limited settings: insights from a training center in a district hospital in Ghana

BMC Women's Health
Background Cervical cancer continues to disproportionately burden women in low/middle-income countries like Ghana. We examined treatment patterns and histopathological outcomes among women screened using visual inspection with acetic acid (VIA) and/or ...
Kofi Effah, Ethel Tekpor, Comfort Mawusi Wormenor, Samuel Adolf Bosoka, Maxwell Afetor, Anita Edinam Dugbazah, Stephen Danyo, Esu Aku Catherine Morkli, Georgina Tay, Bernard Hayford Atuguba, Elorm Kpofo-Tetteh, Chrysantus Kubio, Nana Owusu Mensah Essel   +12 more
doaj   +1 more source

Involvement of FAK-ERK2 signaling pathway in CKAP2-induced proliferation and motility in cervical carcinoma cell lines

Scientific Reports, 2017
Cervical carcinoma is the fourth most common cause of death in woman, caused by human papillomavirus (HPV) infections and arising from the cervix. Cytoskeleton-associated protein 2 (CKAP2), also known as tumor-associated microtubule-associated protein ...
Qi-sang Guo, Yu Song, Ke-qin Hua, Shu-jun Gao   +3 more
doaj   +1 more source

Cervical neuroblastoma [PDF]

Indian Journal of Otolaryngology and Head & Neck Surgery, 2007
Cervical neuroblastoma is relatively uncommon. It present, most often as a firm mass in the lateral neck. Primary neuroblastomas of the neck usually arise in the cervical sympathetic ganglia. They are the sixth most common head and neck extracranial neoplasms. Neuroblastoma is the most common malignancy in children under 1 year of age.
Harjitpal, Singh, C, Mohan, N K, Mohindroo, D R, Sharma   +3 more
openaire   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

High Interleukin-6, Low Cd4+ and Cd8+ T-lymphocytes Expressions as Risk Factors of Cervical Carsinoma Infected by Human Papilloma Virus Type-52 [PDF]

, 2013
In Indonesia cervical carcinoma is the most common cancer in women and one of the leading cause of mortality. High risk human papillomavirus (HPV) is the major risk factor of cervical cancer.
Alit-Artha, A. I. (and), Joewarini, E. (E), Mahendra-Dewi, I. G. (I), Suwiyoga, I. K. (I)   +3 more
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

CACA guidelines for vulvar malignancies

Holistic Integrative Oncology
Objective The purpose of this study is to provide reference and guidance for the clinical diagnosis and treatment of vulvar malignancies. Method This article sorts out and integrates the contents of vulvar malignancies in the field of traditional Chinese
Zhongqiu Lin, Huaiwu Lu, Jing Wang, Xiaofei Tian, Tao Zhu, Bin Li, Kaijiang Liu, Danbo Wang, Yuhao Zhang, Lingling Xie   +9 more
doaj   +1 more source

Placenta Ingestion Enhances Analgesia\ud Produced by Vaginal/Cervical\ud Stimulation in Rats [PDF]

, 1986
Ingestion of placenta has previously been shown to enhance opiate-mediated analgesia (measured as tail-flick latency) induced either by morphine injection or by footshock.
Heller, Steve B., Komisaruk, Dr. Barry R., Kristal, Dr. Mark B., Thompson, Alexis C.   +3 more
core  

Iatrogenic Spinal Cord Injury Resulting From Cervical Spine Surgery. [PDF]

, 2017
STUDY DESIGN: Retrospective cohort study of prospectively collected data. OBJECTIVE: To examine the incidence of iatrogenic spinal cord injury following elective cervical spine surgery.
Arnold, Paul M., Buser, Zorica, Currier, Bradford L., Daniels, Alan H., Fehlings, Michael G., Fish, David E., Hart, Robert A., Hilibrand, Alan S., Lord, Elizabeth L., Mroz, Thomas E., Nassr, Ahmad, Riew, K. Daniel, Sebastian, Arjun S., Stroh, D. Alex, Tortolani, P. Justin, Wang, Jeffrey C.   +15 more
core   +2 more sources