Results 1 to 10 of about 3,782 (114)

Identification of miRNA biomarkers and development of predictive signatures for early detection and prognosis in cervical precancer and cancer [PDF]

Human Genomics
Background Aberrant microRNA expression has been implicated in cervical carcinogenesis, making miRNAs promising biomarkers for early detection and risk stratification of cervical precancer and cancer.
Ebuka Onyenobi, Michael Zhong, Josephine Peitz, Kiranpreet Chawla, Amy Plotkin, Clement Adebamowo, Sally N. Adebamowo   +6 more
doaj   +2 more sources

Feasibility of Intravaginal Artesunate as an Adjuvant HPV & Cervical Precancer Treatment Among Women Living With HIV in Kenya: Study Protocol for a Phase II Clinical Trial [PDF]

Cancer Control
Introduction Cervical cancer disproportionately affects women in low- and middle-income countries (LMICs), who account for 90% of deaths from the disease. Human papillomavirus (HPV) is responsible for 99% of cervical cancer cases.
Annum Sadana BA, Jackton Omoto MBChB, MMed, Katherine Sorgi MA, Lisa Rahangdale MD, MPH, Jennifer S. Smith PhD, Mihaela Plesa BA, CCRP, Chemtai Mungo MD, MPH   +6 more
doaj   +2 more sources

A paper-based HPV E7 oncoprotein assay for cervical precancer detection at the point of care [PDF]

Scientific Reports
Cervical cancer, while preventable through screening and treatment of cervical precancer, remains a global challenge with a disproportionately high burden of disease in resource-limited settings, especially in low- and middle-income countries (LMICs ...
Chelsey A. Smith, Sai Paul, Karen E. Haney, Sonia G. Parra, Meaghan Bond, Leticia López, Mauricio Maza, Juan Felix, Preetha Ramalingam, Pablo Escobar, Philip E. Castle, Kathleen M. Schmeler, Rebecca R. Richards-Kortum   +12 more
doaj   +2 more sources

Women's experiences and acceptability of self-administered, home delivered, intravaginal 5-Fluorouracil cream for cervical precancer treatment in Kenya [PDF]

Frontiers in Reproductive Health
BackgroundInnovative strategies are essential to meet the World Health Organization's 90/70/90 cervical cancer elimination targets, aiming for 90% access to precancer treatment globally by 2030.
Konyin Adewumi, Aparna Ghosh Kachoria, Everlyn Adoyo, Mercy Rop, Mercy Rop, Antony Owaya, Jennifer H. Tang, Jennifer H. Tang, Lisa Rahangdale, Lisa Rahangdale, Lisa Rahangdale, Chemtai Mungo, Chemtai Mungo, Chemtai Mungo   +13 more
doaj   +2 more sources

“There is nothing that can prevent me from supporting her:” men’s perspectives on their involvement and support of women’s use of topical therapy for cervical precancer treatment in Kenya [PDF]

Frontiers in Oncology
PurposeCervical cancer disproportionately impacts women in low- and middle-income countries (LMICs). The World Health Organization’s (WHO) 90/70/90 strategy aims to eliminate cervical cancer by 2030 by increasing HPV vaccination coverage to 90 ...
Chemtai Mungo, Chemtai Mungo, Chemtai Mungo, Konyin Adewumi, Everlyn Adoyo, Graham Zulu, Supreet Kaur Goraya, Cirillus Ogollah, Jackton Omoto, Renée M. Ferrari, Renée M. Ferrari, Lisa Rahangdale, Lisa Rahangdale, Lisa Rahangdale   +13 more
doaj   +2 more sources

Plant Compounds Inhibit the Growth of W12 Cervical Precancer Cells Containing Episomal or Integrant HPV DNA; Tanshinone IIA Synergizes with Curcumin in Cervical Cancer Cells [PDF]

Viruses
This study explores the effects of plant compounds on human papillomavirus (HPV)-induced W12 cervical precancer cells and bioelectric signaling. The aim is to identify effective phytochemicals, both individually and in combination, that can prevent and ...
Linda Saxe Einbond, Jing Zhou, Kunhui Huang, Mario R. Castellanos, Emeka Mbazor, Michael Balick, Hongbao Ma, James A. DeVoti, Stephen Redenti, Hsan-au Wu   +9 more
doaj   +2 more sources

Risk-Based Colposcopy for Cervical Precancer Detection: A Cross-Sectional Multicenter Study in China

Diagnostics, 2022
Recently published guidelines depend upon screening for cervical precancer risk stratification; however, colposcopy provides key information. There is no data from developing countries that could be used comparatively.
Peng Xue, Samuel Seery, Qing Li, Yu Jiang, Youlin Qiao   +4 more
doaj   +1 more source

Clinical applications and utility of ctDNA in cervical cancer and its precursor lesions: from screening to predictive biomarker

Cancer Cell International, 2023
Cervical cancer is a leading cause of gynecological cancer death in the world. Human papillomavirus (HPV) is the most causative factor of cervical cancer. In addition, many genetic factors are involved in cervical cancer development.
Li Li, Yixin Tong, Jianhong Wu, Xiangshang Xu   +3 more
doaj   +1 more source

Colposcopy Findings In High-Grade Cervical Precancer Lesion

Andalas Obstetrics and Gynecology Journal, 2020
Cervical precancer lesion can generally be seen in the transformation zone. Colposcopy allows us to see an image of enlarge precancer lesion in the transformation zone.
Andi Friadi
doaj   +1 more source

Raman Spectroscopy for Early Detection of Cervical Cancer, a Global Women’s Health Issue—A Review

Molecules, 2023
This review focuses on recent advances and future perspectives in the use of Raman spectroscopy for cervical cancer, a global women’s health issue. Cervical cancer is the fourth most common women’s cancer in the world, and unfortunately mainly affects ...
Rubina Shaikh, Amuthachelvi Daniel, Fiona M. Lyng   +2 more
doaj   +1 more source