Genetic and Epigenetic Variations of HPV52 in Cervical Precancer [PDF]
International Journal of Molecular Sciences, 2021 The goal of this study was to identify human papillomavirus (HPV) type 52 genetic and epigenetic changes associated with high-grade cervical precancer and cancer. Patients were selected from the HPV Persistence and Progression (PaP) cohort, a cervical cancer screening program at Kaiser Permanente Northern California (KPNC).
Katharine J. Bee +9 more
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Cervical intraepithelial neoplasia. Clinical analysis
Клинический разбор в общей медицине, 2023 Cervical intraepithelial neoplasia (CIN) is the most relevant topic in cervicology due to the risk of progression to cervical cancer and its rejuvenation.
Tatiana V. Klinyshkova +1 more
doaj +2 more sources
Recurrence of cervical precancer after excisional treatment: risks and prevention
Лечащий ВрачBackground. Genital papillomavirus infection is widespread in the population, initiating the development of precancer and genital cancer. The vast majority (83.0%) of human papillomavirus-related cancer cases worldwide are cervical cancer.
T. V. Klinyshkova, M. S. Buyan
doaj +2 more sources
The HPV Cellular Transactivator Brn-3a Can Be Used to Predict Cervical Adenocarcinoma and Squamous Carcinoma Precancer Lesions in the Developed and Developing Worlds [PDF]
Obstetrics and Gynecology International, 2009 The cellular transactivator Brn-3a has previously been shown to be expressed at elevated levels in the cervix of women with squamous cell carcinoma of the cervix (SCC) and to activate the expression of HPV E6 mRNA.
Daniel Ndisang +5 more
doaj +2 more sources
Using Dynamic Features for Automatic Cervical Precancer Detection [PDF]
Diagnostics, 2021 Cervical cancer remains a major public health concern in developing countries due to financial and human resource constraints. Visual inspection with acetic acid (VIA) of the cervix was widely promoted and routinely used as a low-cost primary screening ...
Roser Viñals +5 more
doaj +5 more sources
Socioeconomic inequalities in cervical precancer screening among women in Ethiopia, Malawi, Rwanda, Tanzania, Zambia and Zimbabwe: analysis of Population-Based HIV Impact Assessment surveys [PDF]
BMJ Open, 2023 Objectives We examined age, residence, education and wealth inequalities and their combinations on cervical precancer screening probabilities for women.
Janne Estill +7 more
doaj +3 more sources
Candidate biomarkers in the cervical vaginal fluid for the (self-)diagnosis of cervical precancer [PDF]
Archives of Gynecology and Obstetrics, 2017 Despite improvement in vaccines against human papilloma virus (HPV), the causative agent of cervical cancer, screening women for cervical precancer will remain indispensable in the coming 30-40 years. A simple test that could be performed at home or at a doctor's practice and that informs the woman whether she is at risk would significantly help make a
Xaveer Van Ostade +3 more
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Cervical Precancer Treatment Outcomes in Cameroon. [PDF]
Int J MCH AIDSBackground and Objective The ablative and excision treatment procedures are effective, accessible, and affordable in resource-constrained settings, but the rollout and posttreatment follow-up are not remarkable. The outcomes of treatment procedures among women treated for precancerous lesions of the cervix have ...
Nkfusai JF +7 more
europepmc +3 more sources
Variations in Genes Encoding Human Papillomavirus Binding Receptors and Susceptibility to Cervical Precancer. [PDF]
Cancer Epidemiol Biomarkers Prev, 2023 BACKGROUND: Cervical cancer oncogenesis starts with human papillomavirus (HPV) cell entry after binding to host cell surface receptors; however, the mechanism is not fully known.
Mukherjee A +14 more
europepmc +2 more sources
Treatment of Cervical Precancers [PDF]
Obstetrics & Gynecology, 2014 Both ablative (cervical cryotherapy, laser ablation) and excisional methods (loop electrosurgical excision procedure, cold knife conization) can be effective at treating cervical precancer. Excisional procedures are associated with adverse obstetric outcomes including preterm delivery and perinatal mortality with the depth of excision potentially ...
Michelle J, Khan, Karen K, Smith-McCune
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