Results 181 to 190 of about 43,554 (264)

Spinal deformities and the "Goel instability concept". [PDF]

J Craniovertebr Junction Spine
Goel A.
europepmc   +1 more source

Microsurgical Unroofing to Secure a Safe Corridor for C1 Screws in Bilateral Ponticulus Posticus: A Case Report. [PDF]

Cureus
Kitagawa K, Maki S, Hozumi T, Ohtori S.
europepmc   +1 more source

TET1 Inhibition Promotes Therapeutic Sensitivity in TP53‐Mutant GBM by Influencing Genome Fragility and Altering TAMs Biology

Advanced Science, Volume 13, Issue 55, 5 October 2026.
In TP53mut GBM cells, reduced P53 function is associated with increased TET1 expression. Genetic or pharmacological inhibition of TET1 correlates with genome fragility, including DNA damage, cellular senescence, telomere shortening, and reactive oxygen species accumulation, which may contribute to increased efficacy of antitumor therapy.
Zhuonan Pu, Jinqiu Liu, Yuxuan Deng, Shuyu Hao, Xiaoli Zhang, Mingxu Yang, Chao Guo, Chao Du, Yingdan Chen, Tai Sun, Nan Ji, Zhengping Zhuang, Jie Feng   +12 more
wiley   +1 more source

Congenital and Breed-Associated Vertebral Anomalies in Dogs and Cats: Developmental Anatomy, Genetic Determinants, and Biological Significance. [PDF]

Life (Basel)
Covașă CT, Grădinaru AC.
europepmc   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

Advanced Science, Volume 13, Issue 57, 14 October 2026.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon, Maria Tsiokou, Patricia Marqués, Enriqueta Rodríguez‐Diaz, Hazel Ang, Federico Pietrocola, Christian G. Riedel   +6 more
wiley   +1 more source

Correlation of examiner judgement and radiological digital pictures in infants with upper cervical spine dysfunction: a cross-sectional study. [PDF]

Pediatr Radiol
Peter J, Csato M, Paravicini I, Wehrli M, Schweinhardt P, Langenfeld A.   +5 more
europepmc   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, Volume 13, Issue 58, 19 October 2026.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Response to the Letter to the Editor: "Ankylosing Spondylitis and Diffuse Idiopathic Skeletal Hyperostosis: Unaddressed Confounders in Postoperative Outcome Studies". [PDF]

Global Spine J
Mahmood A, Ng MK, Berthiaume E, Fano A, Baidya J, Baek G, Rihn JA, Kaye ID, Cha TD, Canseco JA, Hilibrand AS, Vaccaro AR, Kepler CK, Schroeder GD.   +13 more
europepmc   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, Volume 13, Issue 58, 19 October 2026.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

Clinical study of three internal fixation systems via transoral approach for motor function preservation in atlas fractures. [PDF]

J Orthop Surg Res
He Y, Chen H, Gu H, Liu Y, Liang Z, Ma X, Wang J, Zhang K, Tu Q.   +8 more
europepmc   +1 more source