Results 81 to 90 of about 91,813 (306)

Does lowering the screening age for cervical cancer in The Netherlands make sense?\ud [PDF]

, 2008
Recommendations for the age to initiate cervical cancer screening should be directed towards maximum detection of early cervical cancer. However, the screening programme should do more good than harm. The aim of this analysis was to determine whether the
Anttila, Anttila, Arbyn, Arbyn, Arbyn, Barnabas, Bulk, Castle, de Graaf, de Sanjose, Engberts, Franco, Franco, Gustafsson, Haverkos, Jacobs, Kahn, Kyrgiou, Lahelma, Laukkanen, Loos, Miller, Mount, National Cancer Institute, Ostor, Raffle, Rebolj, Rebolj, Rogstad, Sigurdsson, Sigurdsson, Sinclair, Tacken, van Ballegooijen, van Ballegooijen, van Ballegooijen, Walboomers, Webb, Wilson   +38 more
core   +2 more sources

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

Advanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li, Lan Wang, Zihao Zhang, Chunmei Qian, Ning Li, Wei Huang, Qian Ba, Xiaojian Liu, Mayu Sun   +8 more
wiley   +1 more source

Prevalence and associations of sella turcica bridging and cervical vertebral anomalies in lateral cephalometric radiographs: a retrospective study

Folia Morphologica
BACKGROUND: This study aimed to investigate the prevalence of sella turcica bridging (STB), ponticulus posticus, and posterior arch deficiency of the atlas on lateral cephalometric radiographs in an orthodontic population, and to evaluate their ...
Genta Agani Sabah, Yağmur Lena Sezici
doaj   +1 more source

Cervical Trauma Patients with Down Syndrome, Case Report

Forbes Tıp Dergisi, 2020
Dislocations of the atlantooccipital junction are rarely encountered fatal injuries, and occur with high energy traumas. Although atlantoaxial rotational instabilities are mostly seen after upper respiratory tract infections in children, trauma and ...
Erkan Güvenç, Merve Saka Güvenç, Burcu Demirdöven   +2 more
doaj   +1 more source

DTX3L Inhibits the EMT, Metastasis, and Stem‐Like Features of Gastric Cancer Through Promoting GSK‐3β Dependent SNAI1 Decay

Advanced Science, EarlyView.
This research identifies DTX3L as a critical tumor suppressor that inhibits epithelial‐mesenchymal transition (EMT), invasion and metastasis in gastric cancer. By functioning as an E3 ubiquitin ligase, DTX3L targets the master EMT regulator SNAI1 for GSK‐3β‐dependent proteasomal degradation.
Yang Chen, Zhen Li, Jiajia Shen, Jingyu Lin, Xiaoli Zhao, Rui Zhang, Ying Han, Zhen Wang   +7 more
wiley   +1 more source

A Morphological Study of Assimilation of Atlas Vertebrae and their Clinical Implications in Indian Population

Journal of Pharmacy and Bioallied Sciences
Background: Atlas is the first cervical vertebra. Rarely, does the atlas vertebra fuse with the occipital bone, and this occipitalization of the atlas is known as the assimilation of the atlas.
Nishigandha Sadamate, Ravindra Vedpathak, Vilas Chimurkar   +2 more
doaj   +1 more source

Occupational markers and pathology of the castrato singer Gaspare Pacchierotti (1740\u20131821) [PDF]

, 2016
Following the birth of modern opera in Italy in 1600, the demand for soprano voices grew up and the prepuberal castration was carried out to preserve the young male voice into adult life.
RIPPA BONATI, Maurizio, Scattolin, Giuliano, Zampieri, Fabio, Zanatta, Alberto   +3 more
core   +2 more sources

Wireless, Adaptable and Fully Implantable Battery‐powered Devices for Optical Stimulation of the Spinal Cord in Small Rodents

Advanced Science, EarlyView.
Current technologies for spinal cord optogenetic stimulation rely on external power sources and face reliability constraints in freely behaving animals. Here, a fully implantable, battery‐powered optoelectronic device is introduced, enabling operation in any selected environment with wireless recharging for months‐long stimulation.
Shahriar Shalileh, Adan Moallemi, Elham Mohseni Vadeghani, Samuel Tretjakov, Brianna Tsuyuki, Alexander Golab, Benjamin Rever, Wolfram Tetzlaff, Dena Shahriari   +8 more
wiley   +1 more source

Long-Term Follow-up Posthematopoietic Stem Cell Transplantation in a Japanese Patient with Type-VII Mucopolysaccharidosis [PDF]

, 2020
The effectiveness of hematopoietic stem cell transplantation (HSCT) for type-VII mucopolysaccharidosis (MPS VII, Sly syndrome) remains controversial, although recent studies have shown that it has a clinical impact. In 1998, Yamada et al.
Fukao, Toshiyuki, Orii, Kenji, Orii, Tadao, Suzuki, Yasuyuki, Tomatsu, Shunji   +4 more
core   +1 more source

A comprehensive proteome and phosphoproteome atlas across nine organs of the Chinese hamster

Animal Models and Experimental Medicine, EarlyView.
This study presents the first comprehensive proteome and phosphoproteome atlas of the Chinese hamster across nine organs (heart, liver, lung, kidney, spleen, cerebral cortex, skeletal muscle, stomach, and testis or ovary). A total of 14 219 proteins were identified in the proteome, with 11 828 phosphorylated proteins and 47 122 phosphorylation sites ...
Luyao Zhang, Tao Ding, Wanjun Peng, Jie Kong, Xiaoyue Tang, Jiyu Xu, Qiaochu Wang, Zhiyi Zhang, Chunmei Shi, Yizhuo Tian, Huilan Yang, Yehong Yang, Yue Wu, Xiaoyan Liu, Jiangfeng Liu, Juntao Yang   +15 more
wiley   +1 more source