Results 81 to 90 of about 43,554 (264)

Chiari I Malformation: Review and Update of Current Treatment Options

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo   +11 more
wiley   +1 more source

Atlas realignment as novel approach to whiplash recovery: A case study on cervical stability and neurovascular flow

open access: yesInterdisciplinary Neurosurgery
This case report illustrates the significant improvement of a male patient suffering from whiplash-associated disorder (WAD) following atlas vertebral realignment. The patient, who experienced headaches, neck pain, brain fog, a heavy feeling in the head,
Jonathan Verderame   +2 more
doaj   +1 more source

Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning

open access: yesCytoskeleton, EarlyView.
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham   +3 more
wiley   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

open access: yesCytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith   +9 more
wiley   +1 more source

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin   +5 more
wiley   +1 more source

The Effects Of The Cervıcal Headgear On The Cervıcal Vertebrae

open access: yesTurkish Journal of Orthodontics, 1995
In this stduy, the anatomical and postural changes of the cervical vertebrae due to the use of the cervical headgear were investigated. The changes in 10 patients (6 females+4 males) with the CI.II div. 1 malocclusion and the mean age of 9.1 years at the
Sönmez Fıratlı, Mustafa Ülgen
doaj   +1 more source

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard   +3 more
wiley   +1 more source

Posterior Intersegmental Fusion of Unstable Jefferson Fracture

open access: yesGlobal Spine Journal, 2014
Introduction The patient was a 37-year-old man who was a victim of a motor-vehicle accident. On arrival at the emergency department, the patients’ vital signs were all within normal physiological range. His GCS was 15/15.
G. Sharifi   +3 more
doaj   +1 more source

Novel planning pipeline utilizing the Surgical Theater system for pediatric epilepsy surgery

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Advances in the analysis and collation of radiographic datasets have enhanced presurgical planning for various neurosurgical procedures, including clipping of cerebral aneurysms, surgical resection of tumors, and arteriovenous malformation management.
Lisa B. E. Shields   +4 more
wiley   +1 more source

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