Results 61 to 70 of about 42,575 (291)
Advanced Science, EarlyView.We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du +11 more
wiley +1 more source
Contribuição ao estudo das malformações occipito-cervical, particularmente da impressão basilar
Arquivos de Neuro-Psiquiatria, 1952 The authors outline the development of the spine and skull, particularly of axis, atlas and occipital bone. As neuro-skeletal dysmorphisms, the occipito-cervical malformations belong to the neurodysplastic group. They are classified as skeletal anomalies,
Horacio M. Canelas +2 more
doaj +1 more source
TRAUMATIC ATLANTOAXIAL ROTATORY DISLOCATION IN THE PEDIATRIC POPULATION
Coluna/Columna, 2021 Objective: The treatment of C1-C2 rotatory dislocation remains controversial and surgery is rare. Surgical treatment is indicated when the injury satisfies the instability criteria or when it cannot be reduced.
Cristian Illanes
doaj +1 more source
An unexpected cause of palmar paraesthesia in a soldier : a case report [PDF]
, 2015 Athletes presenting with neurological symptoms merit thorough assessments that in most cases will include investigations with one or more imaging modality.
Psaila, Matthew +1 more
core
Advanced Science, EarlyView.Tumor‐derived lactate activates PSCs through MCT1‐mediated Vps34 lactylation and autophagy. These activated PSCs secrete CXCL9/10, upregulating PD‐1 on CD8+ T cells via the CXCR3/STAT3 axis to foster immunosuppression. Disrupting this metabolic crosstalk by targeting MCT1 effectively sensitizes pancreatic cancer to PD‐1 blockade, presenting a promising
Wenfeng Zhuo +14 more
wiley +1 more source
Unusual cause of high cervical myelopathy-C1 arch stenosis
Journal of Craniovertebral Junction and Spine, 2018 Introduction: High cervical myelopathy can be rarely caused by the developmental anomalies of atlas. Patients with C1 arch stenosis can present in early childhood or later in life.
Lokesh S Nehete +6 more
doaj +1 more source
Advanced Science, EarlyView.S100A8/A9‐high macrophages are markedly enriched in the stenotic intestinal tissue of patients with Crohn's disease. These profibrotic macrophages secrete mCCL6 in a STAT3‐dependent manner. mCCL6 and its human ortholog hCCL15 activate fibroblasts via the CCR1 receptor, thereby driving excessive collagen deposition.
Shu Wang +12 more
wiley +1 more source
Fractures of the cervical spine
Clinics, 2013 OBJECTIVES: The aim of this study was to review the literature on cervical spine fractures. METHODS: The literature on the diagnosis, classification, and treatment of lower and upper cervical fractures and dislocations was reviewed.
Raphael Martus Marcon +5 more
doaj +1 more source
Inferior Accessory Ossicle of Anterior Arch of Atlas: Case Report with 3D Visualisation [PDF]
Journal of Clinical and Diagnostic Research, 2019 Inferior accessory ossicle of anterior arch of atlas is a rare, albeit normal variant in relation to the cervical spine, invariably detected incidentally while investigating for other unrelated condition. Its existence should always be kept in mind while
RAHUL DEV, PANKAJ SHARMA, YASRAB KHAN
doaj +1 more source
Advanced Science, EarlyView.Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta +10 more
wiley +1 more source