Results 61 to 70 of about 91,813 (306)

Shoulder pain due to cervical radiculopathy: an underestimated long-term complication of herpes zoster virus reactivation? [PDF]

open access: yes, 2018
Purpose To evaluate if herpes zoster virus (HZV) reactivation may be considered in the aetiology of cervical radiculopathy. Methods The study group was composed of 110 patients (52 M-58F;mean age ± SD:46.5 ± 6.12; range:40-73) with a clinical ...
AS Hilibrand   +34 more
core   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

open access: yesAdvanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang   +7 more
wiley   +1 more source

Spinabifida of atlas

open access: yesNational Journal of Clinical Anatomy, 2012
During the routine osteology demonstration for the first year MBBS students, the authors came across the presence of incomplete posterior arch in one of the atlas.
K Padmalatha   +3 more
doaj   +1 more source

Halofuginone is a Molecular Glue Degrader of Integrin β4

open access: yesAdvanced Science, EarlyView.
Integrin β4 overexpression is linked to aggressive tumors and poor prognosis, but targeted therapies are lacking. We identified halofuginone (HF) as a molecular glue degrader that promotes integrin β4 degradation via the CRL4BWDR18 E3 ligase. HF suppresses tumor progression in vitro and in vivo, offering a new strategy for targeting oncogenic ...
Wei Gong   +8 more
wiley   +1 more source

Research on simulation calculation method of biomechanical characteristics of C1-3 motion segment damage mechanism

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2013
Objective To develop the finite element model (FEM) of cervical spinal C1-3 motion segment, and to make biomechanical finite element analysis (FEA) on C1-3 motion segment and thus simulate the biomechanical characteristics of C1-3 motion segment in ...
Ju-ying HUANG   +3 more
doaj  

TRAUMATIC ATLANTOAXIAL ROTATORY DISLOCATION IN THE PEDIATRIC POPULATION

open access: yesColuna/Columna, 2021
Objective: The treatment of C1-C2 rotatory dislocation remains controversial and surgery is rare. Surgical treatment is indicated when the injury satisfies the instability criteria or when it cannot be reduced.
Cristian Illanes
doaj   +1 more source

Imaging diagnosis: magnetic resonance imaging of diffuse leptomeningeal oligodendrogliomatosis in a dog with "dural tail sign" [PDF]

open access: yes, 2018
A case of diffuse leptomeningeal oligodendrogliomatosis affecting the brain and spinal cord of a dog is presented. A 7.5-year old, male neutered Staffordshire bull terrier presented for evaluation of a chronic history of tetraparesis and seizures, with a
Anwer   +31 more
core   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

Contribuição ao estudo das malformações occipito-cervical, particularmente da impressão basilar

open access: yesArquivos de Neuro-Psiquiatria, 1952
The authors outline the development of the spine and skull, particularly of axis, atlas and occipital bone. As neuro-skeletal dysmorphisms, the occipito-cervical malformations belong to the neurodysplastic group. They are classified as skeletal anomalies,
Horacio M. Canelas   +2 more
doaj   +1 more source

Biomimetic Nanoplatform for Targeted Glioblastoma Therapy via Concurrently Triggering GPX4/DHODH Mediated Ferroptosis

open access: yesAdvanced Science, EarlyView.
Considering the great challenge in Glioblastoma multiforme (GBM) treatment, the authors designed and synthesized a multifunctional nanoplatform that effectively induced ferroptosis by synergetically inhibiting intrinsic intrisinc anti‐ferroptosis proteins, GPX4 & DHODH, and realized excellent in vitro and in vivo anti‐GBM effect.
Guodong Ren   +12 more
wiley   +1 more source

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