Results 121 to 130 of about 5,357,473 (408)

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Visual techniques for cervical cancer screening in Colombia

Biomédica: revista del Instituto Nacional de Salud, 2019
Introduction: Direct visual inspection for cervical cancer screening remains controversial, whereas colposcopy-biopsy is considered the gold standard for diagnosis of preneoplastic cervical lesions.
Óscar Gamboa, Mauricio González, Jairo Bonilla, Joaquín Luna, Raul Murillo, Cervical Cancer Screening Study Group INC   +5 more
doaj   +1 more source

Establishment and biological characterization of radioresistant colorectal cancer cell lines

FEBS Open Bio, EarlyView.
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu, Qing Dai, Jing Leng, Lin Fang, Jing‐Jing Ma, Rui Chen, Che Chen, Peng‐Fei Ran, Wen‐Wen Zhou, Chang Liu, Huang‐Fei Yu   +10 more
wiley   +1 more source

Cervical cancer microbiome analysis: comparing HPV 16 and 18 with other HPV types

Scientific Reports
Differences in the cervicovaginal microbiome may influence the persistence of HPV and therefore, the progression to cervical cancer. We aimed to analyze and compare the metatranscriptome of cervical cancers positive for HPV 16 and 18 with those positive ...
Maire Hidjo, Dhananjay Mukhedkar, Collen Masimirembwa, Jiayao Lei, Laila Sara Arroyo Mühr   +4 more
doaj   +1 more source

Guidelines for cervical cancer screening in China

Gynecology and Obstetrics Clinical Medicine, 2023
In response to the incidence of cervical intraepithelial neoplasia and cervical cancer in China and global screening strategies, a collaborative effort was undertaken by seven Chinese medical associations to develop this guideline for cervical cancer ...
Mingzhu Li, Lihui Wei, Long Sui, Ding Ma, Beihua Kong, Xiaohua Wu, Peng Wu, Youlin Qiao, Fanghui Zhao, Linhong Wang   +9 more
doaj  

Deep Cervix Model Development from Heterogeneous and Partially Labeled Image Datasets [PDF]

arXiv, 2022
Cervical cancer is the fourth most common cancer in women worldwide. The availability of a robust automated cervical image classification system can augment the clinical care provider's limitation in traditional visual inspection with acetic acid (VIA).
arxiv  

Ultrasound-guided trans-rectal high-intensity focused ultrasound (HIFU) for advanced cervical cancer ablation is feasible: a case report. [PDF]

, 2015
High-intensity focused ultrasound (HIFU) is an ablative treatment undergoing assessment for the treatment of benign and malignant disease. We describe the first reported intracavitary HIFU ablation for recurrent, unresectable and symptomatic cervical ...
Abel, M, Abel, P, Ahmed, H, Chen, M, Gedroyc, W, Leen, E, Monzon, L, Park, E, Price, P, Wasan, H   +9 more
core   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Locally advanced cervical cancer complicating early pregnancy: A case of multiple challenges in a limited-resource setting

Gynecologic Oncology Reports, 2023
Carcinoma of the cervix is the most common malignant tumor associated with pregnancy and still poses a complex management problem. Limited data are available on locally advanced cervical cancer outcomes in the first half of pregnancy and how ...
Amira Burhan, Nazik Elmalaika Husian, Rabab Yahia, Liena Abbasher   +3 more
doaj  

A Whole Slide Image Grading Benchmark and Tissue Classification for Cervical Cancer Precursor Lesions with Inter-Observer Variability [PDF]

, 2018
The cervical cancer developing from the precancerous lesions caused by the Human Papilloma Virus (HPV) has been one of the preventable cancers with the help of periodic screening. There are two types of grading conventions widely accepted among pathologists. On the other hand, inter-observer variability is an important issue for final diagnosis.
arxiv   +1 more source