Results 101 to 110 of about 415,432 (310)

Prediction models for high-grade cervical lesions or worse using machine learningResearch in context

EClinicalMedicine
Summary: Background: This study aimed to improve cervical screening efficiency by developing and validating machine-learning models for predicting high-grade cervical lesions or worse (HCL) risk.
Yunyang Deng, Joakim Dillner, Nicholas Baltzer, Laila Sara Arroyo Mühr, Roxana Merino Martinez, Alexander Ploner, Jiayao Lei, Mark Clements   +7 more
doaj   +1 more source

Early detection and prevention

Molecular Oncology, 2019
The rapidly increasing incidence and mortality of cancer calls for a focused effort to increase the effect of cancer‐prevention efforts. In the area of early detection, there are major differences in the preventive impact of implemented screening ...
Joakim Dillner
doaj   +1 more source

Visual techniques for cervical cancer screening in Colombia

Biomédica: revista del Instituto Nacional de Salud, 2019
Introduction: Direct visual inspection for cervical cancer screening remains controversial, whereas colposcopy-biopsy is considered the gold standard for diagnosis of preneoplastic cervical lesions.
Óscar Gamboa, Mauricio González, Jairo Bonilla, Joaquín Luna, Raul Murillo, Cervical Cancer Screening Study Group INC   +5 more
doaj   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

Advanced Healthcare Materials, EarlyView.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He, Nicholas L. Fletcher, Gayathri R. Ediriweera, Yifei Zhu, James Humphries, Christopher B. Howard, Jiazheng Wang, Craig A. Bell, Kristian Kempe, Kristofer J. Thurecht   +9 more
wiley   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

Cervical carcinoma and reproductive factors: Collaborative reanalysis of individual data on 16,563 women with cervical carcinoma and 33,542 women without cervical carcinoma from 25 epidemiological studies [PDF]

, 2006
The International Collaboration of Epidemiological Studies of Cervical Cancer has combined individual data on 11,161 women with invasive carcinoma, 5,402 women with cervical intraepithelial neoplasia (CIN)3/carcinoma in situ and 33,542 women without ...
Silins, Ilvars,, of Epidemiological Studies of Cervical Cancer., International Collaboration, Lund University., Dillner, Joakim,   +3 more
core   +1 more source

Nanoplatforms for Sentinel and Tumor‐Draining Lymph Node Mapping: From Visualization to Pathway‐Informed Staging

Advanced Healthcare Materials, EarlyView.
Lymphotropic nanoplatforms integrate multimodal imaging with therapeutic guidance to map sentinel and tumor‐draining lymph nodes, revealing functional drainage, metastatic involvement, and nodal accessibility, while providing mechanistic insight to support precision surgical and therapeutic interventions.
Xu Chen, Nina Li, Meiyan Zou, Zihao Zhou, Rongwei Xu, Weiyao Feng, Xinyuan Zhao, Li Cui   +7 more
wiley   +1 more source

Exploring the acceptability of two self-sampling devices for human papillomavirus testing in the cervical screening context: a qualitative study of Muslim women in London [PDF]

, 2009
Objectives We explored Muslim women's attitudes to self-sampling for human papillomavirus (HPV) in the context of cervical cancer screening and their responses to two self-sampling devices.Setting A Muslim community centre in north-east London.Methods ...
Cadman, L, Szarewski, A, Ashdown-Barr, L, Waller, J   +3 more
core  

Knowledge, attitudes, and practices regarding cervical cancer and screening among Ethiopian health care workers [PDF]

, 2015
Background: Though cervical cancer incidence has dramatically decreased in resource rich regions due to the implementation of universal screening programs, it remains one of the most common cancers affecting women worldwide and has one of the highest ...
Owen-Smith, Ashli, Blumberg, Henry M., Goedken, Jennifer, Sharling, Lisa, Desalegn, Dawit, Kress, Catherine M.   +5 more
core   +2 more sources

Lack of detectable HPV18 antibodies in 14% of quadrivalent vaccinees in a longitudinal cohort study

npj Vaccines
Although HPV vaccines are highly efficacious, a notable proportion of quadrivalent vaccinees are HPV18 seronegative post-vaccination. We have investigated this findings’ validity by comparing vaccine-induced antibody responses using two different ...
Penelope Gray, Filipe Colaço Mariz, Carina Eklund, Tiina Eriksson, Helena Faust, Hanna Kann, Martin Müller, Jorma Paavonen, Ville N. Pimenoff, Peter Sehr, Heljä-Marja Surcel, Joakim Dillner, Tim Waterboer, Matti Lehtinen   +13 more
doaj   +1 more source