Results 101 to 110 of about 638,968 (308)
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
BMC Women's HealthBackground Incarcerated women face significantly elevated cervical cancer risks compared to the general population due to higher human papillomavirus (HPV) prevalence, limited healthcare access, and socio-demographic vulnerabilities.
Ann-Chatrin Linqvist Leonardsen +5 more
doaj +1 more source
Exploring Iranian women’s perceptions and experiences regarding cervical cancer-preventive behaviors [PDF]
, 2018 Background Preventive behaviors regarding cervical cancer are essential for women’s health. Even though many studies have addressed women’s knowledge and attitudes toward cervical cancer, little information is available about their experiences of ...
Jafari, Fatemeh +3 more
core +3 more sources
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Chromosomal radiosensitivity of human immunodeficiency virus positive/negative cervical cancer patients in South Africa [PDF]
, 2015 Cervical cancer is the second most common cancer amongst South African women and is the leading cause of cancer-associated mortality in this region. Several international studies on radiation-induced DNA damage in lymphocytes of cervical cancer patients ...
Baeyens, Ans +8 more
core +2 more sources
Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt +5 more
wiley +1 more source
Cervical cancer microbiome analysis: comparing HPV 16 and 18 with other HPV types
Scientific ReportsDifferences in the cervicovaginal microbiome may influence the persistence of HPV and therefore, the progression to cervical cancer. We aimed to analyze and compare the metatranscriptome of cervical cancers positive for HPV 16 and 18 with those positive ...
Maire Hidjo +4 more
doaj +1 more source
Early detection and prevention
Molecular Oncology, 2019 The rapidly increasing incidence and mortality of cancer calls for a focused effort to increase the effect of cancer‐prevention efforts. In the area of early detection, there are major differences in the preventive impact of implemented screening ...
Joakim Dillner
doaj +1 more source
Visual techniques for cervical cancer screening in Colombia
Biomédica: revista del Instituto Nacional de Salud, 2019 Introduction: Direct visual inspection for cervical cancer screening remains controversial, whereas colposcopy-biopsy is considered the gold standard for diagnosis of preneoplastic cervical lesions.
Óscar Gamboa +5 more
doaj +1 more source