Results 91 to 100 of about 638,968 (308)

Effect of Percutaneous Nephrostomy in Late Stage Cervical Cancer's Survival with Impaired Renal Function [PDF]

, 2016
Objective: explore the association between percutaneous nephrostomy and survival of patients with advanced cervical cancer accompanied by renal impairment.Materials and Methods: Retrospective cohort, with 70 samples taken with consecutive sampling.
Gunawan, A. (Ali), Rasjidi, I. (Imam), Susanto, C. (Christine)   +2 more
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Evidence from Outcomes: Gender-Neutral 2vHPV Vaccination at Moderate Coverage Drives Rapid Depletion of HPV16/18 Among Vaccinated and Unvaccinated Women

Viruses
Human papillomavirus (HPV) vaccination may eventually eradicate oncogenic vaccine-targeted HPVs but only with a strategy that also protects unvaccinated individuals.
Matti Lehtinen, Ville N. Pimenoff, Tiina Eriksson, Camilla Lagheden, Anna Söderlund-Strand, Heljä-Marja Surcel, Joakim Dillner   +6 more
doaj   +1 more source

High-grade cervical dysplasia in pregnancy – psychological and medical challenges [PDF]

, 2017
Despite being rare, the incidence of pregnancy-related cancer is expected to rise as women continue to delay childbearing and give birth later in their reproductive years.
Bacalbasa, Nicolae, Balalau, Denisa O., Banu, Petrisor, Bălălău, Cristian, Ples, Liana, Sima, Romina M., Stanescu, Anca D.   +6 more
core   +4 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Researchers should no longer delay implementation of Pap screening in low and middle income countries pending research into novel screening approaches

Infectious Agents and Cancer
A study coordinated by Groesbeck Parham and Mark Schiffman describes a novel approach to single-visit, point-of-care cervical screening and triage for low and middle income countries (LMICs) that uses an HPV screening test that is not affordable in LMICs
Eric J Suba
doaj   +1 more source

Genome-wide methylome analysis using MethylCap-seq uncovers 4 hypermethylated markers with high sensitivity for both adeno- and squamous-cell cervical carcinoma [PDF]

, 2016
Background: Cytology-based screening methods for cervical adenocarcinoma (ADC) and to a lesser extent squamous-cell carcinoma (SCC) suffer from low sensitivity.
Boers, Aniek, De Meyer, Tim, Klip, Harry G, Schuuring, Ed, Steenbergen, Renske DM, Van Criekinge, Wim, van der Zee, Ate GJ, van Leeuwen, Robert W, Wang, Rong, Wisman, G Bea A   +9 more
core   +2 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

HPV self-sampling for cervical cancer screening during wartime: a pilot implementation study from a conflict-affected region of Ukraine

BMJ Global Health
Introduction Cervical cancer screening is difficult to initiate and sustain during war due to disrupted health services, population displacement and limited clinical capacity.
Joakim Dillner, Laila Sara Arroyo Mühr, Olexiy Kovalyov, Kostyantyn Kovalyov, Olena Deinichenko   +4 more
doaj   +1 more source

Cervical cancer risk factors among HIV-infected Nigerian women [PDF]

, 2013
Background: Cervical cancer is the third most common cancer among women worldwide, and in Nigeria it is the second most common female cancer. Cervical cancer is an AIDS-defining cancer; however, HIV only marginally increases the risk of cervical pre ...
Adebamowo, Clement, Almujtaba, Maryam, Blattner, William, Dakum, Patrick, Lawal, Ishak, Modibbo, Fatima, Offiong, Richard, Olaniyan, Olayinka, Ononogbu, Uzoma, Spiegelman, Donna   +9 more
core   +2 more sources