Results 71 to 80 of about 415,432 (310)

Clients' returning for cervical screening results : a focus group study exploring the reasons why women spontaneously return for their results at the Khayelitsha Cervical Cancer Screening Project [PDF]

, 2004
Bibliography: leaves 112-123.Cervical cancer is integrally associated with the problems of poverty in the developing world. It is the most common cancer cause of death among women in these regions.
Honikman, Simone
core  

Cervical carcinoma and sexual behavior : collaborative reanalysis of individual data on 15,461 women with cervical carcinoma and 29,164 women without cervical carcinoma from 21 epidemiological studies [PDF]

, 2009
High-risk human papillomavirus (HPV) types cause most cervical carcinomas and are sexually transmitted. Sexual behavior therefore affects HPV exposure and its cancer sequelae.
V. Beral, D. Colin, J. Peto, S. Sweetland, J. Green, P. Appleby, C. La Vecchia, M. Plummer, S. Franceschi, International Collaboration of Epidemiological Studies of Cervical Cancer, A. Berrington de González   +10 more
core   +1 more source

Concomitant human papillomavirus (HPV) vaccination and screening for elimination of HPV and cervical cancer

Nature Communications
HPV vaccination with concomitant HPV-based screening of young women has been proposed for faster cervical cancer elimination. We describe the baseline results of a population-based trial of this strategy to reduce the incidence of HPV.
Laila Sara Arroyo Mühr, Andrea Gini, Emel Yilmaz, Sadaf S. Hassan, Camilla Lagheden, Emilie Hultin, Ainhoa Garcia Serrano, Agustin E. Ure, Helena Andersson, Roxana Merino, K. Miriam Elfström, Iacopo Baussano, Joakim Dillner   +12 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Human papillomavirus infection induces NF-κB activation in cervical cancer: A comparison with penile cancer [PDF]

, 2010
This study aimed to determine the relationship between human papillomavirus (HPV) and nuclear factor-κB (NF-κB) in cervical cancer using 62 tissues of cervical cancer, and to compare the findings to penile cancer.
KAN TORIYAMA, Morimoto, Konosuke, SHUICHI FUJITA, Wada, Akihiro, AKIHIRO WADA, Mori, Naoki, Senba, Masachika, KONOSUKE MORIMOTO, MASACHIKA SENBA, NAOKI MORI, Toriyama, Kan, NATHAN BUZIBA, Buziba, Nathan, Fujita, Shuichi   +13 more
core   +1 more source

Evidence from Outcomes: Gender-Neutral 2vHPV Vaccination at Moderate Coverage Drives Rapid Depletion of HPV16/18 Among Vaccinated and Unvaccinated Women

Viruses
Human papillomavirus (HPV) vaccination may eventually eradicate oncogenic vaccine-targeted HPVs but only with a strategy that also protects unvaccinated individuals.
Matti Lehtinen, Ville N. Pimenoff, Tiina Eriksson, Camilla Lagheden, Anna Söderlund-Strand, Heljä-Marja Surcel, Joakim Dillner   +6 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

The influence of methyl donor status on cervical cancer cell behaviour in vitro [PDF]

, 2013
Epidemiological studies suggest that the availability of methyl-donor nutrients may influence the risk of cervical cancer and of cancer progression. This effect may be mediated by altered DNA instability and aberrant DNA methylation.
Poomipark, Natwadee
core  

Researchers should no longer delay implementation of Pap screening in low and middle income countries pending research into novel screening approaches

Infectious Agents and Cancer
A study coordinated by Groesbeck Parham and Mark Schiffman describes a novel approach to single-visit, point-of-care cervical screening and triage for low and middle income countries (LMICs) that uses an HPV screening test that is not affordable in LMICs
Eric J Suba
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source