Results 51 to 60 of about 415,432 (310)

CIN coexisting with AIS is a risk factor for residual disease after conization for cervical adenocarcinoma in situ

Frontiers in Oncology
IntroductionCompared to definitive hysterectomy, cervical conization with negative margin remains a controversial management for AIS currently. Our study aimed to evaluate (1) the effect of conization with negative margin alone or subsequent hysterectomy,
Rong Zeng, Yulin Guo, Miao Zou, Chaonan Wang, Xufeng Wu   +4 more
doaj   +1 more source

Trial of a Rare Diagnosis in a Core Needle Biopsy of Breast

Clinical Pathology, 2021
Objective: Mucinous carcinoma is a rare, special subtype of breast carcinoma associated with a good prognosis. It often presents a confusing appearance with a benign process. For all these reasons, differential diagnosis could be challenging. Case Report:
Karima Idrissi Serhrouchni, Jinane Kharmoum, Mariame Chraibi, Ouafae karmouni, Fayrouz Rabhi, Fatima Zahra Soussi   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Treatment Outcome of Cervical Cancer Patients at Ocean Road Cancer Institute, Dar es salaam [PDF]

, 2011
Cervical cancer is the second commonest malignancy in females globally. Cancer of the cervix has a devastating impact on women’s health in developing countries especially Africa since more than 75% of the worldwide burden of the disease occurs in these ...
Majinge, Peter MC
core  

Interobserver variability and accuracy of p16/Ki-67 dual immunocytochemical staining on conventional cervical smears

Diagnostic Pathology, 2019
Background p16/Ki-67 dual immunocytochemical staining (DS) has been proven as a sensitive and specific test for triage of HPV positive women with good reproducibility and accuracy.
Veronika Kloboves Prevodnik, Tine Jerman, Nataša Nolde, Alenka Repše Fokter, Sandra Jezeršek, Živa Pohar Marinšek, Ulrika Klopčič, Simona Hutter Čelik, Kristina Gornik Kramberger, Maja Primic Žakelj, Urška Ivanuš   +10 more
doaj   +1 more source

Guidelines for cervical cancer screening in China

Gynecology and Obstetrics Clinical Medicine, 2023
In response to the incidence of cervical intraepithelial neoplasia and cervical cancer in China and global screening strategies, a collaborative effort was undertaken by seven Chinese medical associations to develop this guideline for cervical cancer ...
Mingzhu Li, Lihui Wei, Long Sui, Ding Ma, Beihua Kong, Xiaohua Wu, Peng Wu, Youlin Qiao, Fanghui Zhao, Linhong Wang   +9 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Cervical screening in Australia 2011-2012 [PDF]

, 2014
This report presents the latest national statistics monitoring the National Cervical Screening Program, which aims to reduce incidence, morbidity and mortality from cervical cancer.

core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Expanding access to HPV screening through community health insurance schemes: lessons from a screening exercise for teachers in Ghana

BMC Health Services Research
Background Cervical cancer (CC) screening uptake remains low primarily owing to the absence of organized screening and lack of insurance coverage. Members of the Ghana National Association of Teachers (GNAT) contribute monthly to an insurance scheme ...
Kofi Effah, Ethel Tekpor, Joseph Emmanuel Amuah, Elagbe Goka, Comfort Mawusi Wormenor, Richard Armah, Seyram Kemawor, Stephen Danyo, Annita Edinam Dugbazah, Nana Owusu Mensah Essel, Emmanuel Timmy Donkoh   +10 more
doaj   +1 more source